Insidermedicine Daily News (Video)

Clopidogrel Video: Protein Linked to Alzheimer's Found, Double Dose Clopidogrel Reduces Heart Attack Risk, Less Sleep For Young Adults May Mean Mental Distress

Wed, 1 Sep 2010 17:00:00 EDT

(September 1, 2010 - Insidermedicine)

From New York - A new report published in Nature identifies a new target in the fight against Alzheimer's disease. Scientists discovered that the gamma-secretase activating protein (GSAP) stimulates beta-amyloid formation. They found that reducing GSAP also reduced beta amyloid.

From Hamilton - Doubling the dose of clopidogrel during angioplasty reduces risk of cardiovascular death, according to a report published in the Lancet. Researchers compared double dose clopidogrel to standard dose in patients undergoing PCI, finding that double dosing reduced risk of heart attack, stroke and cardiovascular death by 14%.

And finally, from Australia - Less sleep for young adults may be connected to mental distress, according to a report published in SLEEP. Studying nearly 21,000 young adults, researchers found that sleeping less than eight hours a night had a linear association with psychological distress.

Heart Attack Video: DASH Diet Reduces Heart Attack Risk, Low Heparin Dose During PCI Does Not Reduce Bleeding, Benefits of Exercise for Obese

Tue, 31 Aug 2010 17:00:00 EDT

(August 31, 2010 - Insidermedicine)

From Baltimore - The DASH eating plan reduces long term heart attack risk, according to a report published in Circulation: Cardiovascular Quality and Outcomes. Researchers found that DASH--an eating plan that emphasizes fruits, vegetables, whole grains, fish, low fat dairy products,poultry and nuts while limiting fats, red meet and sugar--lowered bad cholesterol and blood pressure, and reduced 10 year heart attack risk by 18%.

From Hamilton - Lower dose heparin during balloon angioplasty does not reduce risk of bleeding, according to a report published in the Journal of the American Medical Association.
Studying over 2000 patients who underwent PCI, researchers found that patients who received a low dose of the anticoagulant heparin during the procedure had no reduced risk of major bleeding

And finally, from the UK - People genetically predisposed to obesity benefit greatly from exercise, according to a report published in Public Library of Science Medicine. Studying over 20,000 people, researchers found that exercise reduced genetic predisposition to obesity by 40%.

ALS Video: Genetic Variant Connected to Lou Gehrig's Disease, African Americans At Higher Risk Following Stenting, Omega 3 Fatty Acid Margarine Not Beneficial For Heart

Mon, 30 Aug 2010 19:00:00 EDT

(August 30, 2010 - Insidermedicine)

From Bethesda - A new report published in The Lancet Neurology identifies a genetic factor associated with amyotrophic lateral sclerosis. Researchers compared over 400 ALS patients to nearly 500 controls and found two genetic variations occurring in 70% of ALS patients with a family history of the disease.

From Washington - According to a report published in Circulation: Journal of the American Heart Association, African Americans are at raised risk of blood clotting after receiving a drug eluting stent. Studying over 7,200 patients who underwent stenting, researchers found that African Americans had 3x increased risk of clotting following the procedure.

And finally, from the Netherlands - Margarines with omega 3 fatty acids do not appear to reduce cardiovascular risk, according to a report published in the New England Journal of Medicine. Researchers studied more than 5,000 patients who had a previous heart attack, finding that adding margarine with omega-3 fatty acids did nothing to prevent a second heart attack or stroke.

Salmonella Video: Certain Antivirals OK During Early Pregnancy, Egg Recall in US Expanded, Migraine Linked to Stroke and Heart Attack (Week in Review, Part Two)

Sun, 29 Aug 2010 17:00:00 EDT

(August 29, 2010 - Insidermedicine)

From Denmark - Certain antiviral drugs taken during pregnancy do not appear to cause birth defects, according to a report published in the Journal of the American Medical Association. Researchers studied nearly 900,000 births, finding that only 2.2% of children exposed to acyclovir, valacyclovir and famciclovir in the womb during the first trimester had a major birth defect, compared with 2.4% among those not exposed.

From Washington - Two more brands of eggs have been added to the large egg recall in the US. Cardenas Market and Trafficanda Egg Ranch products have now been recalled, amidst concerns over salmonella.

And finally, from Iceland - Migraine with aura raises risk of cardiovascular death, according to a report published in the British Medical Journal. Researchers studied nearly 19,000 adults, finding that sufferers of migraine with aura were at increased risk of dying from heart disease or stroke.

Rosiglitazone Video: Mental Health Issues in Pregnancy Linked to Small Baby, Risks of Avandia and Actos, Heart Transplant Survival Rates in Certain Patients (Week in Review, Part One)

Sat, 28 Aug 2010 17:00:00 EDT

(August 28, 2010 - Insidermedicine)

From Bangladesh - Women with mental health issues are more likely to have smaller babies, according to a report published in BMC Public Health. Studying over 700 women, researchers found that those who suffered either depression or anxiety during pregnancy were much more likely to have smaller babies

And finally, from Boston - Hypertrophic cardiomyopathy patients have high survival rates from heart transplant , according to a report published in Circulation: Heart Failure. Studying over 26,000 transplant patients, researchers found that survival rates for HCM patients was 85% at 1 year post surgery, 75% at 5 years, and 61% at 10 years.

Pregnancy Video: Meconium Indicative of Gestational Smoke Exposure, Type 2 Diabetics At Raised Risk of Alzheimer's, Egg Recall Expanded

Thu, 26 Aug 2010 19:00:00 EDT

(August 26, 2010 - Insidermedicine)

From North Carolina - Meconium can indicate how much a mother smoked during pregnancy, according to a report published in Environmental Health. Studying meconium samples of 337 babies, researchers found that the tobacco smoke metabolites found in the tarry stool were indicative of the amount of gestational exposure to cigarette smoke.

From Minnesota - According to a report published in Neurology, people with insulin resistance and type 2 diabetes are at raised risk of Alzheimer's disease. Researchers studied 135 elderly patients for 10-15 years, finding that those who had type 2 diabetes and insulin resistance were more likely to develop plaques in the brain associated with Alzheimer's disease.

And finally, from Washington - Two more brands of eggs have been added to the large egg recall in the US. Cardenas Market and Trafficanda Egg Ranch products have now been recalled, amidst concerns over salmonella.

Melanoma Video: Novel Therapy Shrinks Tumors in Advanced Melanoma, Depression and Anxiety in Pregnancy Linked to Smaller Babies, Migraine Raises Risk of Cardiovascular Death

Wed, 25 Aug 2010 19:00:00 EDT

(August 25, 2010 - Insidermedicine)

From New York - A new report published in the New England Journal of Medicine describes a novel therapy for advanced melanoma. Researchers found that the new targeted therapy called PLX4032--which works by blocking the BRAF protein--significantly shrank tumors in 80% of 32 patients studied.

From Bangladesh - Women with mental health issues are more likely to have smaller babies, according to a report published in BMC Public Health. Studying over 700 women, researchers found that those who suffered either depression or anxiety during pregnancy were much more likely to have smaller babies.

Fuch's Dystrophy Video: Scientists Find Genetic Variation Associated With Fuch's Dystrophy

Wed, 25 Aug 2010 19:00:00 EDT

(August 25, 2010 - Insidermedicine)

A genetic anomaly associated with an eye disease that damages the cornea has been identified in research that appears online ahead of print in the New England Journal of Medicine.

Here is some information about Fuchs disease:

•    It is an eye disease that generally starts causing problems in those aged 40 and older

•    The initial signs are cloudy vision, which progresses into the emergence of tiny bumps and then painful blisters on the cornea

•    It is a leading cause of the need for corneal transplant surgery

Researchers from the University of Oregon conducted a genetic analysis of nearly 300 individuals with Fuchs disease who had undergone corneal transplantation as a result of their disease. The investigators then compared these findings with the results of a genetic analysis they conducted on over 400 individuals without the condition.

An alteration in a gene known as transcription factor 4, or TCF4, was present more frequently among those with Fuchs than those without. In fact, having this alteration could increase one’s risk of Fuchs by up to 200 times. While the manner in which this genetic alteration produces Fuchs remains unclear, the investigators did identify two proteins that are likely to be involved, giving them new targets for further study.

Today’s research helps clarify the biological underpinnings of a poorly understood eye disease.

Avandia Video: Comparing Risks of Rosiglitazone and Pioglitazone, Certain Antivirals OK During Early Pregnancy, Heart Transplant Survival Rates for Cardiomyopathy Patients

Tue, 24 Aug 2010 17:00:00 EDT

(August 24, 2010 - Insidermedicine)

From Delaware - A new report published in Circulation: Cardiovascular Quality and Outcomes compares risk with rosiglitazone and pioglitazone. Studying over 36,000 patients, researchers found that risk of a heart attack, heart failure, both or death were about 4% for each medication.

From Denmark - Certain antiviral drugs taken during pregnancy do not appear to cause birth defects, according to a report published in the Journal of the American Medical Association. Researchers studied nearly 900,000 births, finding that only 2.2% of children exposed to acyclovir, valacyclovir and famciclovir in the womb during the first trimester had a major birth defect, compared with 2.4% among those not exposed.

Breast Cancer Video: Nicotine Linked to Breast Cancer, Alzheimer's Reversed in Mice by Rheumatoid Arthritis, Genetic Impact of Vitamin D

Mon, 23 Aug 2010 17:00:00 EDT

(August 23, 2010 - Insidermedicine)

From Taiwan - A new report published in the Journal of the National Cancer Institute links nicotine to breast cancer. Studying nearly 300 breast tumors, researchers found that when nicotine binds to the nicotinic acetylcholine receptor it promoted the growth of breast cancer cells.

From Florida - Rheumatoid arthritis reverses Alzheimer's disease in mice, according to a study published in the Journal of Alzheimer's Disease. Researchers studied mice bred to develop Alzheimer's, finding that injections of GM-CSF--a signaling protein released during RA--reduced beta amyloid and greatly improved memory in the rodents.

And finally, from the UK - A new report published in Genome Research outlines the genetic impact of vitamin D. Researchers found that vitamin D affects 229 genes--among them, genes known to be associated with multiple sclerosis, Crohn's disease and type 1 diabetes.

ALS Video: Experimental Method to Eradicate HIV Cells, Cutting Cather Infections in Hospitals, Recurrent Head Trauma May Mimic Lou Gehrig's Disease (Week in Review, Part Two)

Sun, 22 Aug 2010 17:00:00 EDT

(August 22, 2010 - Insidermedicine)

From Michigan - Reminding hospital staff to remove catheters greatly decreases infections, according to a report published in Clinical Infectious Diseases. Researchers found that a system that reminded health care staff to routinely remove catheters cut catheter associated urinary tract infections in half.

And finally, from Boston - Repeated concussions may cause a condition that mimics amyotrophic lateral sclerosis--or, Lou Gehrig's disease, according to a report published in the Journal of Neuropathology and Experimental Neurology. Researchers studied 12 deceased athletes, finding that 3 who had been diagnosed with ALS actually had a different fatal disease, one cause by repeated head trauma.

Heart Failure Video: Red Meat Linked to Heart Disease, Hearing Loss Prominent Among US Teens, Chocolate Lowers Heart Failure Risk (Week in Review, Part One)

Sat, 21 Aug 2010 17:00:00 EDT

(August 21, 2010 - Insidermedicine)

And finally, from Sweden - According to a report published in Circulation: Heart Failure, eating a little bit of chocolate may lower risk of heart failure. Researchers studied nearly 32,000 middle aged and elderly women, finding that those who ate one to two servings of high quality chocolate each week had a 32% reduced risk of heart failure.

Smoking Video: Even Low Levels of Smoke Exposure Raise Lung Disease Risk, Pesticide Exposure While in Womb Raises Risk of ADHD, Some Smoking Cessation Tactics May Fail

Fri, 20 Aug 2010 17:00:00 EDT

(August 20, 2010 - Insidermedicine)

From New York - Casual smoking or exposure to secondhand smoke may raise risk of lung disease, according to a report published in the American Journal of Respiratory and Critical Care Medicine. Studying nonsmokers, active smokers and low exposure smokers, and found that even the lowest levels of exposure were associated with genetic abnormalities.

From California - According to a report published in Environmental Health Perspectives, prenatal exposure to pesticides raises risk of attention problems. Researchers found that mothers who had higher levels of pesticide metabolites while pregnant were more likely to have a child that, at age 5, would demonstrate symptoms indicative of ADHD.

And finally, from London - A new report published in Psychological Science outlines the difficulty of quitting smoking. Researchers told one group of smokers attempting to quit to suppress all thoughts about smoking, finding that this method only led to a significant increase in smoking once they stopped suppressing these thoughts.

Diabetes Video: Green Leafy Vegetables Lower Diabetes Risk, Binge Drinking Dangerous for Hypertensives, Cervical Cancer Treatment Advancement

Thu, 19 Aug 2010 19:00:00 EDT

(August 19, 2010 - Insidermedicine)

From the UK - Eating green leafy vegetables reduces risk of diabetes, according to a report published in the British Medical Journal. Researchers reviewed several studies covering over 220,000 people, finding that one and a half extra servings of green leafy vegetables a day was associated with a 14% decreased risk of type 2 diabetes.

From South Korea - Hypertensive men who binge drink are at increased risk of death, according to a report published in Stroke: Journal of the American Heart Association. Studying over 6100 men over 55 years old, researchers found those who had high blood pressure and were binge drinkers had a 4x increased risk of death.

And finally, from the UK - A new report from the University of Leicester outlines a major step forward in the fight against cervical cancer. Research of over 1400 cervical cancer patients revealed that adding cisplatin to radiotherapy treatment reduced risk of dying from the disease by 23%.

HIV Video: Experimental Approach to Eliminate HIV, Benefits of End of Life Care For Lung Cancer Patients, Concussions May Mimic ALS

Wed, 18 Aug 2010 19:00:00 EDT

(August 18, 2010 - Insidermedicine)

From Israel - A new report published in AIDS Research & Therapy describes an experimental new approach to eliminating HIV. While current HIV treatments only aim to delay the onset of AIDS, new lab research was able to integrate HIV DNA into the human genome and thereby activate apoptosis (or, self destruction) of the HIV cells.

From Massachusetts - Palliative care for lung cancer patients greatly improves quality of life and survival, according to a report published in the New England Journal of Medicine. Researchers studied over 150 metastatic lung cancer patients, finding that those who received palliative care suffered less depression and survived longer than those receiving standard care.

And finally, from Boston - Repeated concussions may cause a condition that mimics amyotrophic lateral sclerosis--or, Lou Gehrig's disease, according to a report published in the Journal of Neuropathology and Experimental Neurology. Researchers studied 12 deceased athletes, finding that 3 who had been diagnosed with ALS actually had a different fatal disease, one cause by repeated head trauma.

Hearing Loss Video: Rising Rates of Hearing Loss Among US Teens, New Measures Cut Catheter Infections in Half, Aggressive Breast Cancer Genes Found

Tue, 17 Aug 2010 17:00:00 EDT

(August 17, 2010 - Insidermedicine)

From Boston - Hearing loss has increased significantly among US adolescents, according to a report published in the Journal of the American Medical Association. Researchers compared records from 1988-1994 to 2005-2006, finding a 31% increase in hearing loss among 12-19 year olds.

From Michigan - Reminding hospital staff to remove catheters greatly decreases infections, according to a report published in Clinical Infectious Diseases. Researchers found that a system that reminded health care staff to routinely remove catheters cut catheter associated urinary tract infections in half.

And finally, from Sweden - A new report published in Clinical Cancer Research identifies genes that may be connected to aggressive breast cancer. Studying the tumors of nearly 100 breast cancer patients, researchers found 12 genes in particular that were more prominent in patients who had aggressive disease.

Heart Disease Video: Red Meat Raises Heart Disease Risk, Aggressive Nature Connected to Heart Attack and Stroke, Chocolate Lowers Chances of Heart Failure

Mon, 16 Aug 2010 17:00:00 EDT

(August 16, 2010 - Insidermedicine)

From Boston - Substituting protein rich foods for red meat decreases risk of heart disease, according to a report published in Circulation: Journal of the American Heart Association. In a study of over 84,000 women, researchers found that those who had two servings of red meat a day had 30% increased risk of heart disease when compared to women who had only a half a serving. As well, substituting fish, nuts or poultry for red meat all reduced risk of heart disease.

From Baltimore - Aggressive people may be at increased risk of heart attack and stroke, according to a report published in Hypertension: Journal of the American Heart Association. Researchers studied over 5600 people and found that those who scored low on agreeableness and high on antagonistic scores were at 40% raised risk of having thickened carotid arteries, a known risk factor for cardiovascular events.

And finally, from Sweden - According to a report published in Circulation: Heart Failure, eating a little bit of chocolate may lower risk of heart failure. Researchers studied nearly 32,000 middle aged and elderly women, finding that those who ate one to two servings of high quality chocolate each week had a 32% reduced risk of heart failure.

Cold Weather Raises Heart Attack Risk, OCT Used In Angioplasty Improves Operation, H1N1 Pandemic Over (Week in Review)

Sun, 15 Aug 2010 17:00:00 EDT

(August 15, 2010 - Insidermedicine)

And finally, from Geneva - The H1N1 pandemic is officially over, according to the World Health Organization. The absence of out-of-season H1N1 outbreaks, the waning intensity of outbreaks, and an adequate level of community acquired immunity to the virus are the reasons the declaration was made.

Blood Pressure Video: Expensive Blood Pressure Meds No Better than Generic, Dry Pet Food and Salmonella Risk, Cancer Biomarkers and False Discoveries

Sat, 14 Aug 2010 17:00:00 EDT

(August 14, 2010 - Insidermedicine)

From China - New expensive blood pressure meds performed no better than generic diuretics in a new study presented at the China Heart Congress and International Heart Forum. Researchers randomized over 33,000 hypertensive patients to a generic diuretic or either an ACE inhibitor or calcium channel blocker. Results of 8 year follow up showed that the ACE inhibitor was linked with a 20% higher death rate from stroke, while the calcium channel blocker had a 12% increased risk of heart failure.

From Atlanta - Pet food can raise risk of salmonella infections, according to a report published in Pediatrics. Researchers found that dry pet food caused a minor salmonella outbreak from 2006-2008, with nearly half of the cases occurring in children 2 years old and younger.

And finally, from Toronto - According to a report published in the Journal of the National Cancer Institute, cancer biomarkers--though frequently discussed--fail to be of actual use. Researchers found that many investigations yield 'false discoveries' and as a result, no new cancer biomarkers have been approved for clinical use in the last 25 years.

Estrogen Video: Persistently Raised Heart Rate Increases Death Risk, Estrogen Not Connected to Lung Cancer, Many Benefits of Walking to School

Fri, 13 Aug 2010 17:00:00 EDT

(August 13, 2010 - Insidermedicine)

From New York - Persistently raised heart rate increases risk of death, according to a report published in the European Heart Journal. Researchers studied nearly 10,000 patients for 5 years, finding that a heart rate of 84 beats per minute or more that developed or persisted during the study period brought a 55% increased risk of cardiovascular death and a 79% increased risk of all-cause death.

From Los Angeles - Estrogen use is not connected to lung cancer among postmenopausal women, according to a report published in The Journal of the National Cancer Institute. Studying nearly 11,000 postmenopausal women with previous hysterectomies, researchers found no lung cancer or mortality risk from estrogen use.

And finally, from New York - According to a report published in Medicine & Science in Sports & Exercise, walking to school can help children in many ways. Researchers studied 20 boys and 20 girls aged 10-14, finding that children who walked to school experienced reduced stress and had improved blood pressure and heat rate while taking an exam.

Angioplasty Video: New Imaging Technique Improves Angioplasty, New Rheumatoid Arthritis Criteria, H1N1 Pandemic Officially Over

Wed, 11 Aug 2010 19:00:00 EDT

(August 11, 2010 - Insidermedicine)

From Maryland - Advances in imaging may greatly enhance angioplasty, according to a report published in Review of Scientific Instruments. Researchers added optical coherence tomography to the baloon tipped catheter normally inserted into the arteries to flatten plaque and improve blood flow, thereby making it possible to monitor the inflation of the balloon itself.

From Atlanta - The American College of Rheumatology has released new rheumatoid arthritis classification criteria. Researchers updated criteria from 1987 to reflect recent advances regarding RA--the intent to identify the condition early on in order to prevent joint damage.

And finally, from Geneva - The H1N1 pandemic is officially over, according to the World Health Organization. The absence of out-of-season H1N1 outbreaks, the waning intensity of outbreaks, and an adequate level of community acquired immunity to the virus are the reasons the declaration was made.

Heart Attack Risk Rises When Temperature Falls, Hormone Therapy And Breast Cancer Risk, Hospital Related MRSA Infections Falling (Video)

Tue, 10 Aug 2010 19:00:00 EDT

(August 10, 2010 - Insidermedicine)

From the UK - Cool weather increases risk of heat attack, according to a report published in the British Medical Journal. Researchers studied over 84000 heart attack cases, finding that every 1 degree celsius decrease was associated with approx. 200 more heart attacks.

From California - A new report published in Cancer Epidemiology, Biomarkers & Prevention links hormone therapy to breast cancer. Studying nearly 3,000 women, researchers found that taking estrogen therapy for 15+ years increased breast cancer risk by 19%, while estrogen plus progestin for the same time period increased risk by 83%.

And finally, from Atlanta - According to a report published in the Journal of the American Medical Association, health care associated MRSA cases are decreasing. Researchers studied MRSA cases from 2005-2008, finding a 28% reduction in hospital related infections over that time period.

Pregnancy Video: Weight Loss During Pregnancy Linked to Heavy Baby, B Vitamin Give No Reduced Stroke Risk, Protein Deficiency Linked to Grim Breast Cancer Prognosis (Week in Review)

Sun, 8 Aug 2010 17:00:00 EDT

From Australia – According to a report published in The Lancet Neurology, vitamin b supplements do not reduce the risk of cardiovascular events in stroke patients. Researchers randomized over 8100 stroke and TIA patients to either daily B vitamin supplements or a placebo. They found little difference between the two groups in the number of strokes, heart attacks or vascular deaths that occurred.(August 8, 2010 - Insidermedicine)

From Boston - Maternal weight gain may predict high birth rate, according to a report published in The Lancet. Researchers studied over 500,000 women and 1,000,000 infants, finding that women who gained over 40 lbs during pregnancy were 1.7x more likely to have a baby with a high birth weight, while those who gained over 50 lbs had 2.3x increased risk.

And finally, from North Carolina - According to a report published in Science Translational Medicine, low levels of a certain protein may predict aggressive breast cancer. Researchers studied over 800 breast cancer patients, finding that low levels of the iron regulating protein was associated with an increased risk for aggressive, recurring cancer.

Blindness Video: Possible Cure for Degenerative Eye Diseases, Genetic Cause for Chronic Pain, Childhood Behavior Predictive of Adult Behavior

Sat, 7 Aug 2010 17:00:00 EDT

(August 7, 2010 - Insidermedicine)

From Virginia - Scientists may have discovered a cure for degenerative vision diseases, according to research released by the Office of Naval Research. Researchers manipulated certain proteins in mice with macular degeneration, finding that the process successfully repaired the retina and restored vision

From Israel - A new report published Genome Research identifies a genetic cause for chronic pain. Studying mice, researchers found that the Cacgn2 gene was associated with susceptibility to chronic pain.

And finally, from California - According to a report published in Social Psychological and Personality Science, childhood personality may predict adult behavior. Researchers examined video taped interviews of 2400 children from a 1960 study, interviewing 144 participants 40 years later. They found that personality traits exhibited in early childhood strongly predicted adult personality and behavior.

Miscarriage Video: Pregnancy Possible Following Miscarriage, Schizophrenia Genetic Marker, Strategies to Reduce Dementia

Fri, 6 Aug 2010 17:00:00 EDT

(August 6, 2010 - Insidermedicine)

From Scotland - According to a report published in the British Medical Journal, women do not need to wait to get pregnant again following a miscarriage. Researchers studied over 30,000 women, finding that those who got pregnant within 6 months of a miscarriage were most likely to have a healthy pregnancy.

From Atlanta - Scientists have identified a genetic marker associated with schizophrenia, according to a report published in the American Journal of Human Genetics. Studying DNA of schizophrenic patients, researchers found that a specific genetic deletion that was strongly associated with risk for schizophrenia.

And finally, from France - A new report published in the British Medical Journal outlines targets aimed at reducing the prevalence of dementia. Researchers studied over 1400 healthy people, finding that eliminating depression and diabetes and eating more fruits and vegetables reduced new dementia cases by 21%, and that increasing education reduced 18% of new cases.

H1N1 Video: Mutation Explains H1N1 Pandemic, Hungry Children More Likely to Suffer Poor Health, Danger of Household Cleaning Products Decreases

Thu, 5 Aug 2010 19:00:00 EDT

(August 5, 2010 - Insidermedicine)

From Wisconsin - A new report published in PLoS Pathogens outlines why the H1N1 flu virus spread so well to humans. Researchers found that the H1N1 virus is actually a combination of avian and swine flu viruses, with traces of the 1918 pandemic virus, that was able to make the jump from animals to humans due to a mutation of an avian protein.

From Bethesda - Hungry children are at increased risk of illness later in life, according to a report published in the Archives of Pediatric and Adolescent Medicine. Researchers studied nearly 6,000 children for 10 years, finding that those who went hungry in early childhood had over 2x increased risk of poor general health.

And finally, from Ohio - Household cleaning products still cause a significant amount of childhood injuries, according to a report published in Pediatrics. Researchers found that early childhood injuries from cleaning products in the last 20 years have been cut in half, however, spray bottles remain a problem and primary source of injury.

Cholesterol Video: Gene Variants Connected to Cholesterol and Triglycerides, Pregnancy Weight Gain Linked to Heavier Baby, Protein Predictive of Aggressive Breast Cancer

Wed, 4 Aug 2010 19:00:00 EDT

(August 4, 2010 - Insidermedicine)

From Michigan - Scientists have identified a host of gene variants connected to cholesterol and triglycerides, according to a report published in Nature. Researchers reviewed over 45 studies covering more than 100,000 people. They found 95 genetic variants associated with triglycerides and cholesterol levels.

Stroke Video: Vitamin B Supplementation Has No Reduced Cardiovascular Risk, Chili Peppers Good For High Blood Pressure, Triglycerides Rise According to Circadian Clock

Tue, 3 Aug 2010 18:30:00 EDT

(August 3, 2010 - Insidermedicine)

From China – Chili peppers may be good for high blood pressure, according to a report published in Cell Metabolism. Researchers found that long term consumption of capsaicin (a main component of chili peppers) was able to lower blood pressure in a hypertensive animal model.

And finally, from New York – Triglycerides might rise when an individual’s circadian clock is disrupted, according to a report published in Cell Metabolism. Researchers found that mice with ‘broken’ circadian clocks had constantly elevated triglycerides over 24 hours.

Epilepsy Video: Three Newer Epilepsy Drugs Raise Suicide Risk, Sleep Disorder Causes Parkinson's, Dementia, Preterm Babies and Lung Complications (Week in Review)

Sun, 1 Aug 2010 17:00:00 EDT

(August 1, 2010 - Insidermedicine)

From Minnesota - Three epilepsy drugs may raise risk of suicide, according to a report published in Neurology. Studying over 44,000 people who had at least one prescription for an epilepsy drug, researchers found that the newer medications levetiracetam, topiramate and vigabatrin had a 3x increased risk of harming themselves or attempting suicide

From Minnesota – A sleep disorder may predict dementia and Parkinson’s later in life, according to a report published in Neurology. Researchers studied 27 people who experienced rapid eye movement sleep disorder, finding that 13 developed Parkinson’s, 13 developed dementia and 1 developed multiple system atrophy.

And finally, from Chicago - Infants born in the late preterm period are more likely to suffer respiratory illness, according to a report published in the Journal of the American Medical Association. Researchers studied over 230,000 deliveries over a 6 year period, finding that babies born at 34 weeks had a 40x increased risk of respiratory distress syndrome, while the risk of the condition decreased for every additional week spent in the womb.

Daptomycin Video: Protein in Urine Raises Risk of Kidney Injury, FDA Warning Over IV Drug Daptomycin, H1N1 Pandemic Flu Virtually Only Strain During Last Flu Season

Fri, 30 Jul 2010 17:00:00 EDT

(July 30, 2010 - Insidermedicine)

From Baltimore – According to a report published in the Journal of the American Society of Nephrology, protein in the urine may predict kidney injury. Researchers studied over 11,000 adults, finding that the preexisting condition glomerular filtration raised risk of acute kidney injury by sevenfold.

From Washington – The FDA is reporting that daptomycin may raise risk of pneumonia. Based on medical literature, researchers found that the IV antibiotic daptomycin (Cubicin) caused seven cases of eosinophilic pneumonia and must now come with a warning label.

And finally, from Atlanta – According to a report published in the CDC's Morbidity and Mortality Weekly Report, H1N1 was virtually the only type of influenza circulating in the 2009-2010 season. Researchers analyzed over 67,000 influenza A specimens, finding that nearly 99.8% were of the H1N1 pandemic strain.

Rosiglitazone Video: Certain Diabetes Drugs Linked to Fracture Risk, Sleep Disorder Predicts Dementia and Parkinson's Disease, Risks of Home Birth

Thu, 29 Jul 2010 19:00:00 EDT

(July 29, 2010 - Insidermedicine)

From Michigan – According to a report published in the Journal of Clinical Endocrinology & Metabolism, certain diabetes drugs may raise risk of fractures. Researchers studied over 3000 diabetes patients, nearly 800 of whom had a fracture. Results showed that women over the ageof 50 taking thiazolidinediones were at significant raised risk of fractures.

And finally, from the UK – An editorial published in The Lancet outlines the risk of home births. Researchers examined a meta analysis comparing birth outcomes among low risk healthy women . They found that, while home births are safe for the mother and do have multiple benefits, they were associated with 2x the risk of neonatal death

Parkinson's Disease Video: Molecular Pathway Linked to Parkinson's Disease, Relationships Boost Survival Odds, Delirium Raises Risk of Death in Older Patients

Wed, 28 Jul 2010 19:00:00 EDT

From California - Scientists have identified a molecular mechanism that may cause Parkinson's disease, according to a report published in Nature. Researchers found that the LRRK2 genetic mutation results in impaired activity of microRNA molecules. This impairment results in the death of nerve cells that are responsible for secretion of dopamine in the brain--a distinctive feature of Parkinson's disease.

From Utah - Social relationships may extend your life, according to a report published in PLoS Medicine. Conducting a meta analysis of nearly 150 studies, researchers found that social relationships with friends, family, neighbors or colleagues, increased chances of survival by 50%.

And finally, from the Netherlands - According to a report published in the Journal of the American Medical Association, older patients who suffer from delirirum are at increased risk of negative outcomes. Researchers compared over 700 delirium patients to nearly 2300 controls, finding that those who suffered from the condition were at increased risk of institutionalization, dementia and death.

Rheumatoid Arthritis Video: Alcohol Linked to Reduced Rheumatoid Arthritis Severity, Three Epilepsy Drugs Raise Suicide Risk, Preterm Newborns and Respiratory Illness

Tue, 27 Jul 2010 19:15:00 EDT

(July 27, 2010 - Insidermedicine)

From the UK - Alcohol consumption may reduce severity of rheumatoid arthritis, according to a report published in Rheumatology. Researchers compared nearly 900 RA patients to over 100 healthy controls, finding that those who drank alcohol had considerably less problems from their RA than non-drinkers. Results also showed that those who did not drink at all had a 4x increased risk of developing the condition.

From Minnesota - Three epilepsy drugs may raise risk of suicide, according to a report published in Neurology. Studying over 44,000 people who had at least one prescription for an epilepsy drug, researchers found that the newer medications levetiracetam, topiramate and vigabatrin had a 3x increased risk of harming themselves or attempting suicide

And finally, from Chicago - Infants born in the late preterm period are more likely to suffer respiratory illness, according to a report published in the Journal of the American Medical Association. Researchers studied over 230,000 deliveries over a 6 year period, finding that babies born at 34 weeks had a 40x increased risk of respiratory distress syndrome, while the risk of the condition decreased for every additional week spent in the womb.

Cancer Video: Childhood Cancer Survivor's Heart Risk, Most Prostate Cancer Patients Get Aggressive Treatment, Education Lowers Risk of Dementia

Mon, 26 Jul 2010 19:00:00 EDT

(July 26, 2010 - Insidermedicine)

From the Netherlands - According to a report published in the Archives of Internal Medicine, childhood cancer survivors may face long term heart problems. Researchers studied 601 childhood cancer survivors, finding that 27% suffered abnormal cardiac function during long term followup.

From New Jersey - Most low risk prostate cancer patients typically undergo aggressive therapy, according to a report published in the Archives of Internal Medicine. Based on a study of over 123,000 prostate cancer patients, researchers estimate that 83% of men would receive aggressive treatment of the disease, even though only 2% of them would high grade cancer.

And finally, from the UK - Increased education may lower risk of dementia, according to a report published in Brain. Researchers studied nearly 900 people, finding that for every additional year of education, individuals saw their risk of dementia decrease by 11%.

Child Abuse Video: Flying Safe for Heart Patients, PTSD More Common in Older Women than Men, Giving Kids Pharmaceuticals A Form of Abuse (Week in Review)

Sun, 25 Jul 2010 17:00:00 EDT

(July 25, 2010 - Insidermedicine)

From Denmark - Women are more prone to PTSD later in life than men, according to a report published in the Annals of General Psychiatry. Researchers studied over 6500 adults, finding that PTSD was 2x more common in women than men, and that women were most vulnerable between ages 51 to 55 compared with ages 41-45 in men.

And finally, from Denver - Parents giving their children medications for non-therapeutic reasons is a common, but largely unreported, form of abuse, according to a report published in the Journal of Pediatrics. Researchers reviewed data from US poison control, finding 160 cases yearly of malicious pharmaceutical use in young children.

Cesarean Section Video: Vaginal Birth Safe After Cesarean Section, Sitting Too Much May Mean Higher Risk of Death, Malicious Pharmaceutical Use in Children

Sat, 24 Jul 2010 17:00:00 EDT

(July 24, 2010 - Insidermedicine)

From Washington - The American College of Obstetricians and Gynecologist have released new guidelines regarding vaginal birth after cesarean. The organization now states that most women who have previously undergone a c-section are safe to attempt vaginal birth in a subsequent pregnancy. Evaluation of risks/benefits in each patient, however, is essential.

From Atlanta - Sitting too much during down time may increase risk of death, according to a report published in the American Journal of Epidemiology. Researchers studied over 120,000 adults for 14 years, finding that people who sat over 6 hours per day during their spare time were much more likely to die during the study period.

And finally, from Denver - Parents giving their children medications for non-therapeutic reasons is a common, but largely unreported, form of abuse, according to a report published in The Journal of Pediatrics. Researchers reviewed data from US poison control, finding 160 cases yearly of malicious pharmaceutical use in young children.

Diabetes Video: Bone Resorption Regulates Blood Sugar, African Descent Increases Risk of Aggressive Breast Cancer, Blood Test for Depression Possible

Fri, 23 Jul 2010 17:00:00 EDT

(July 23, 2010 - Insidermedicine)

From New York – According to a report published in Cell, scientists have discovered that bone resorption regulates blood sugar. Researchers found that when skeleton regrowth triggers destruction of old bone, it also stimulates the body to release insulin and thereby improve glucose uptake. These results could lead to a new target in the fight against diabetes.

From Michigan – African and African American women are more likely to develop high risk breast cancer, according to a report published in Cancer. Researchers compared over 500 African American and 75 African breast cancer patients with over 1000 white American breast cancer patients They found that 82% of the African women 26% of the African American women had triple negative breast cancer, compared with only 16% of the white American women.

And finally, from the Netherlands – Scientists may be close to a blood test for depression, according to a report published in Biological Psychiatry. Researchers compared unmedicated major depressive disorder patients to healthy controls, finding that an experimental blood test was able to identify seven genes that could distinguish the depressed patients from the controls.

Alzheimer's Video: Gene Connected to Alzheimer's Disease, HDL Cholesterol Levels Irrelevant in Some, Torn ACL May Not Require Immediate Surgery

Thu, 22 Jul 2010 19:00:00 EDT

(July 22, 2010 - Insidermedicine)

From Massachusetts – Scientists have discovered a gene associated with the development Alzheimer’s disease, according to a report published in Cell. Researchers found that when the SITR1 gene was overproduced in mice genetically engineered to have Alzheimer's, the rodent's learning and memory problems improved.

From Boston – High levels of good cholesterol may be irrelevant in certain patients, according to a report published in The Lancet. Studying patients participating in the JUPITER trial, researchers found that high HDL cholesterol levels did not appear to reduce risk of cardiovascular events in patients who had already had their LDL cholesterol lowered with rosuvastatin.

And finally, from Sweden – Torn ACLs do not need to be operated on immediately, according to a report published in the New England Journal of Medicine. Researchers randomized over 120 adults with a torn ACL to receive immediate surgery or rehab therapy and optional deferred surgery. Results showed that both groups fared equally well after two years, with 60% of the rehab group avoiding surgery altogether.

Heart Disease Video: Flying OK for Heart Patients, Large Waists and High Triglycerides Increase Heart Disease Risk, Work Related Deaths Dropping Dramatically

Wed, 21 Jul 2010 17:00:00 EDT

(July 21, 2010 - Insidermedicine)

From England - New guidelines published in the journal Heart maintain that flying is safe for heart patients. Experts reviewed several studies, finding that heart disease patients, people with heart rhythm abnormalities and those at high risk for heart attack face no added threat to their heart from air travel.

From Quebec - Large waistlines and raised triglycerides increase risk of heart disease, according to a report published in Canadian Medical Association Journal. Researchers studied over 21,000 individuals, finding that larger waistlines and high triglycerides both independently raised risk of heart disease, and when combined, represented the highest risk for the condition.

And finally, from England - According to a report published in Occupational and Environmental Medicine, work related deaths from disease and injury have dramatically decreased. From 1979 to 2000, researchers found that work related deaths--such as cancer, liver and lung problems--decreased from 733 yearly to 471.

Ovarian Cancer Video: Genetic Marker Predicts Ovarian Cancer, PTSD More Common Among Older Women than Men, Combat Inflicted Brain Injury May Lead to Epilepsy

Tue, 20 Jul 2010 19:00:00 EDT

(July 20, 2010 - Insidermedicine)

From Connecticut - Scientists have identified a genetic marker that may predict ovarian cancer, according to a report published in Cancer Research. Scientists discovered that 25% of ovarian cancer patients had a variant of the KRAS oncogene compared with only 6% of the general population. As well, this variant was found in 61% of patients who also had a family history of breast and ovarian cancer.

From Denmark - Women are more prone to PTSD later in life than men, according to a report published in the Annals of General Psychiatry. Researchers studied over 6500 adults, finding that PTSD was 2x more common in women than men, and that women were most vulnerable between ages 51 to 55 compared with ages 41-45 in men.

And finally, from Minnesota - According to a report published in Neurology, combat inflicted brain injuries increase a soldier's risk of epilepsy later in life. Researchers studied nearly 200 veterans, all of whom experienced a brain injury in combat 35 years prior to the study. Results showed that 44% of soldiers developed post-traumatic epilepsy.

Bevacizumab Video: Chemo Plus Bevacizumab Safe For Lung Cancer Treatment, Cleaning Materials Connected to Breast Cancer Risk, Obesity Linked to Psoriatic Arthritis

Mon, 19 Jul 2010 19:00:00 EDT

(July 19, 2010 - Insidermedicine)

From Italy - Bevacizumab plus chemotherapy is safe for some lung cancer patients, according to a report published in The Lancet Oncology. Researchers studied over 2200 patients suffering from non-squamous non small cell lung cancer. Results confirmed that the combination of bevacizumab and chemotherapy is a safe first line treatment of the disease.

From Massachusetts - Cleaning materials may raise risk of breast cancer, according to a report published in Environmental Health. Surveying over 1500 women, half of whom had breast cancer, researchers found that women who used the most combined cleaning products had a 2x increased risk of breast cancer.

And finally, from Utah - According to a report published in the Archives of Dermatology, obesity at age 18 may lead to psoriatic arthritis later in life. Researchers studied nearly 1000 psoriasis patients, finding that 20% of those who were obese in early adulthood developed psoriatic arthritis by age 35.

Rosiglitazone Video: Avandia Stays on the Market, Long Term Death Risk for Childhood Cancer Survivors, Stroke Risk Rises Following Alcohol Consumption

Sun, 18 Jul 2010 16:00:00 EDT

(July 18, 2010 - Insidermedicine)

And finally, from Boston - Risk of stroke increases immediately following alcohol consumption, according to a report published in Stroke: Journal of the American Heart Association. Researchers studied nearly 400 stroke patients, finding that risk of stroke doubled an hour after drinking alcohol.

Asthma Video: Suicide Risk Higher for Asthma Sufferers, Early HIV Treatment Dramatically Reduces Death Risk, Weight Loss Improves Hot Flushes

Sat, 17 Jul 2010 17:00:00 EDT

(July 17, 2010 - Insidermedicine)

From Taiwan - Asthma sufferers may be more likely to commit suicide, according to a report published in the American Journal of Psychiatry. Researchers studied over 160,000 teenage students for 12 years, finding that risk of suicide was more than twofold for those with asthma.
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From New York - Early HIV treatment dramatically reduces risk of death, according to a report published in the New England Journal of Medicine. Studying over 800 HIV patients, researchers found that early treatment of the disease resulted in 75% reduced risk of death.

And finally, from California - Weight loss may improve hot flushes in postmenopausal women, according to a report published in the Archives of Internal Medicine. Researchers studied over 300 overweight postmenopausal women, finding that a weight loss intervention program helped one third of patients with bothersome hot flushes.

Stroke Video: Early Urine Test Best for Diabetic Kidney Disease Patients, Insufficient Vitamin D Worldwide, Alcohol Increases Risk of Stroke

Fri, 16 Jul 2010 17:00:00 EDT

(July 16, 2010 - Insidermedicine)

From the Netherlands - According to a report published in the Journal of the American Society of Nephrology, taking a urine test in the morning is the best method to monitor diabetic kidney disease patients. Researchers studied 700 type 2 diabetics suffering from kidney disease, finding that a first morning albumin:creatinine urine test was the best method to identify kidney function decline.

From California - A new report published in Endocrine Today estimates the amount of people worldwide who do not get enough vitamin D. Researchers found that 50% of North Americans and Western Europeans get insufficient vitamin D.

And finally, from Boston - Risk of stroke increases immediately following alcohol consumption, according to a report published in Stroke: Journal of the American Heart Association. Researchers studied nearly 400 stroke patients, finding that risk of stroke doubled an hour after drinking alcohol.

Avandia Video: Avandia to Remain on the Market, Babies Born Outside Normal Working Hours Face Higher Death Risk, Arthroscopic Surgery for Athletes with Hip Problem

Thu, 15 Jul 2010 19:00:00 EDT

(July 15, 2010 - Insidermedicine)

From Washington - The FDA is allowing Avandia (rosiglitazone) to stay on the market, following an advisory panel review. A 33 member panel voted to keep the diabetes medication on the market, on the condition that it be closely supervised. Avandia has recently come under fire due to concerns regarding adverse cardiovascular events.

From Scotland - The time and day a baby is born may affect their chance of survival, according to a report published in the British Medical Journal. Scottish researchers studied over a million births and infant deaths, finding that babies born outside of Monday to Friday, 9-5 working hours were at raised risk of dying from lack of oxygen.

And finally, from Providence - According to a report presented at the meeting of the American Orthopaedic Society for Sports Medicine, athletes with a common hip problem can return to play following arthroscopic surgery. Researchers studied 47 patients with hip impingement, finding that 78% of athletes returned to play 9 months following their surgery, with 92% returning to their previous level of competition.

Obesity Video: Being Obese Affects Memory in Women, Genetic Effect of Smoking Explained, Positive Lifestyle Change Interventions Preferred by Obese People

Wed, 14 Jul 2010 19:00:00 EDT

(July 14, 2010 - Insidermedicine)

From Chicago -Being obese may affect a woman's memory and brain function, according to a report published in the Journal of the American Geriatrics Society. Researchers studied over 8700 postmenopausal women, finding that for every one point increase in a participant's BMI, her score on a memory test would drop by one point.

From Texas - A new study published in BMC Medical Genomics outlines the genetic effect of smoking cigarettes. Researchers studied the white blood cells of over 1200 people, finding that those who smoked had noticeable changes in the expression of genes known to involved in immune response, cancer and natural killer cell signaling.

And finally, from Australia - Obese people prefer positive lifestyle-change interventions more than ones that only promote weight loss, according to a report published in BMC Public Health. Researchers surveyed nearly 150 obese adults, finding that participants preferred interventions that were non-judgmental and encouraged lifestyle changes more than ones that were stigmatizing, and focused solely on losing weight.

Cancer Video: Childhood Cancer Survivors and Long Term Risk of Death, Obesity at 20 Raises Risk of Premature Death, Low Vitamin D Levels Linked to Cognitive Decline

Tue, 13 Jul 2010 17:00:00 EDT

(July 13, 2010 - Insidermedicine)

From England - According to a report published in the Journal of the American Medical Association, childhood cancer survivors are at increased risk of dying after 25 years. Researchers followed nearly 18,000 childhood cancer patients, finding that survivors were more likely to die from second primary cancers and cardiac causes 25 years following their diagnosis.

From Sweden - Men who are obese at age 20 are at significantly increased risk of premature death, according to a report presented at the International Congress on Obesity. Researchers compared nearly 2000 obese males to 3600 males who were not obese, finding that obesity at age 20 was associated with a 2x increased risk of premature death.

And finally, from England - According to a report published in the Archives of Internal Medicine, low vitamin d levels may raise risk of cognitive decline in older adults. Researchers studied over 800 people over 65 years old, finding that those who had extremely low vitamin d levels were at 60% increased risk of substantial cognitive decline.

Stroke Video: MRI Beats CT Scan For Stroke Diagnosis, Sleep Apnea Raises Risk of Heart Disease, Foods with Vitamin E May Lower Dementia Risk

Mon, 12 Jul 2010 17:00:00 EDT

(July 12, 2010 - Insidermedicine)

From Germany - New guidelines released by the American Academy of Neurology prefer MRI to CT scan for stroke diagnosis. Researchers reviewed several studies, finding that MRI correctly diagnosed stroke 83% of the time, while CT scan was only successful 26% of the time.

From Boston - According to a report published in Circulation: Journal of the American Heart Association, sleep apnea may increase risk of heart disease later in in life. Studying nearly 4500 adults for over 8 years, researchers found that those with obstructive sleep apnea were at 68% increased risk of eventually developing heart disease.

And finally, from the Netherlands - Vitamin E rich foods may lower dementia risk, according to a report published in the Archives of Neurology. Following nearly 5400 adults aged 55 or older, researchers found that those who ate foods rich in Vitamin E such as butter, sunflower oil, and mayonnaise had a 25% reduced risk of dementia.

Asthma Video: Genetic Ancestry Aids Asthma Diagnosis, Too Much TV Time May Affect Attention in Kids, Living Conditions Change Shrinks Tumors in Mice with Cancer

Thu, 8 Jul 2010 17:00:00 EDT

(July 8, 2010 - Insidermedicine)

From Florida - According to a report published in the New England Journal of Medicine, genetic data improves diagnosis of asthma and lung disease. Researchers studied over 3000 African American patients and found that their precise genetic ancestry was connected to pulmonary measurements.

From Iowa - Too much television and video games may lead to attention problems in children, according to a report published in Pediatrics. Researchers studied over 1300 children, finding that those who were in front of the television screen for over two hours a day had up to 2x increased risk of having attention problems.

And finally, from Ohio - According to a report published in the journal Cell, changing living conditions in rodents with cancer appears to shrink their tumors. Researchers studied 20 mice with cancer, finding that switching them to a bigger space and providing them with more things to do actually shrank tumor mass by 77% and volume by 43%.

Glucosamine Video: Blood Pressure Control Outcomes in Certain Patients, Glucosamine Not Beneficial For Chronic Low Back Pain, Antioxidants Good for the Arteries

Wed, 7 Jul 2010 17:00:00 EDT

(July 7, 2010 - Insidermedicine)

From Florida - A new report published in the Journal of the American Medical Association outlines blood pressure control outcomes for certain patients. Researchers studied 6400 patients with both diabetes and coronary artery disease, finding that maintaining blood pressure at less than 130 mm Hg did not improve their risk of cardiovascular events and death.

From Norway - The drug glucosamine does not appear to help patients with chronic low back pain, according to a report published in the Journal of the American Medical Association. Researchers studied 250 chronic low back pain patients, randomizing half to glucosamine and half to placebo. Results showed little difference between the two groups, in respect to pain and quality of life.

And finally, from Israel - According to a report published in Nutrition and Metabolism, antioxidants are good for your arteries. Researchers studied 70 adults, finding that antioxidant supplementation resulted in more elastic arteries, as well as improved blood sugar and cholesterol profiles.

Heart Disease Video: Fast Food Ads Targeting Children On the Rise, Clusterin Linked to Alzheimer's Disease, Anxiety Increases Death Risk for Heart Disease Patients

Mon, 5 Jul 2010 17:00:00 EDT

(July 5, 2010 - Insidermedicine)

From Chicago – According to a report published in the Archives of Pediatrics & Adolescent Medicine, though children now see less ads for sweets and beverages, they also see more for fast foods. Researchers studied advertisements targeted towards children aged 2-5 between 2003 and 2007, finding that sweet ads decreased by 41%, beverage ads decreased by up to 30% but fast food ads increased by 4.7%.

From the UK – A protein found in the blood plasma has been connected to the development of Alzheimer’s disease, according to a report published in the Archives of General Psychiatry. Studying nearly 500 Alzheimer’s patients, researchers found an association between high concentrations of the protein cluster in Alzheimer’s development and severity.

And finally, from The Netherlands – Anxiety increases risk of heart attack and stroke in heart disease patients, according to a report published in the Archives of General Psychiatry. Researchers studied over 1000 heart disease patients, finding a 74% increased risk of cardiovascular events and death among those with general anxiety disorder.

Rosiglitazone Video: Biking and Brisk Walking Controls Weight, RA Drug Anakinra Reduces Stroke Damage to Brain, Rosiglitazone Raises Risk of Cardiovascular Events (Week in Review)

Sun, 4 Jul 2010 17:00:00 EDT

(July 4, 2010 - Insidermedicine)

From Boston – According to a report published in the Archives of Internal Medicine, biking and brisk walking help women stave off weight gain. Researchers studied over 18,000 women for 16 years, finding that both biking and brisk walking reduced participant’s likelihood of gaining weight, though this association was not found for slow walking.

From the UK - A rheumatoid arthritis drug also reduces damage incurred by stroke, according to a report presented at the annual lecture of The Physiological Society. Lab research has shown that the rheumatoid arthritis drug 'anakinra' reduces brain damage suffered from stroke by blocking the IL-1 protein.

And finally, from Maryland – According to a report published in the Journal of the American Medical Association, the diabetes medication rosiglitazone may increase risk of cardiovascular events. Researchers studied data on over 220,000 patients on rosiglitazone or pioglitazone. Results showed that rosiglitazone was associated with 1.25x increased risk of heart failure, 1.27 increased risk of stroke, and 1.14x increased risk of death.

Stroke Video: Exercise Early in Life May Prevent Cognitive Impairment in Women, Rheumatoid Arthritis Drug Anakinra Reduces Stroke Brain Damage, America's Obesity Problem

Thu, 1 Jul 2010 17:00:00 EDT

(July 1, 2010 - Insidermedicine)

From Toronto - According to a report published in the Journal of the American Geriatrics Society, physically active women are less likely to develop cognitive impairment later in life. Researchers studied nearly 10,000 women at several points in their lives, finding that physical activity particularly in teenage years--but also at age 30 and 50--reduced risk of late life cognitive impairment.

From the UK - A rheumatoid arthritis drug also reduces damage incurred by stroke, according to a report presented at the annual lecture of The Physiological Society. Lab research has shown that the rheumatoid arthritis drug 'anakinra' reduces brain damage suffered from stroke by blocking the IL-1 protein.

And finally, from Washington - According to a report released by Trust for America's Health and the Robert Wood Johnson Foundation, obesity rates in the US are still increasing. Researchers studied obesity rates from 2006-2009, finding that obesity rates increased in 28 states, and that 67% of adults and 33% of children and teenagers are obese.

Diabetes Video: Near Normal Target Levels for Diabetics, Alcohol Exposure in Womb Linked to Sperm Reduction Later, Improvements Needed in End of Life Care

Wed, 30 Jun 2010 17:00:00 EDT

(June 30, 2010 - Insidermedicine)

From Orlando - According to a report presented that American Diabetes Association meeting, near normal blood sugar targets for type 2 diabetics does not delay organ damage. Researchers studied over 10,000 adults with longstanding type 2 diabetes, finding that lowering their blood sugar levels to near normal did not affect their risk of developing damage to their eyes, kidneys, or nerves.

From Italy - Women who drink while pregnant may affect semen quality of their sons, according to a report presented at the European Society of Human Reproduction and Embryology. Researchers followed nearly 12,000 women and their sons born between 1984 and 1987. They found that sons of mothers who drank 4.5 or more drinks per week had one third lower sperm concentration that those not exposed to alcohol in the womb.

And finally, from California - According to a report published in the Archives of Internal Medicine, end of life care may need improvement. Researchers studied nearly 500 adults who were hospitalized at least three days prior to dying. Though 70% of end of life goals were met, researchers did find that clinicians were not up to par in communicating with patients and their friends and family.

Rosiglitazone Video: Biking, Brisk Walking Staves of Weight Gain in Women, Type 1 Diabetes Treatment Improving, Rosiglitazone Raises Risk of Cardiovascular Events

Mon, 28 Jun 2010 17:00:00 EDT

(June 28, 2010 - Insidermedicine)

From Orlando – Type 1 diabetes death rates are decreasing, according to a report presented at the American Diabetes Association meeting. Researchers followed nearly 1100 people diagnosed with type 1 diabetes between 1965 and 1979. They found that the more recent a person was diagnosed, the less likely they were to die—an aspect that underlines the advances in treatment and care of diabetes.

Whooping Cough Video: New Diabetics Face Liver Disease Risk, Cancer Risk Cut with Coffee Consumption, California's Whooping Cough Epidemic (Week in Review)

Sun, 27 Jun 2010 17:00:00 EDT

(June 27, 2010 - Insidermedicine)

And finally, from California - Whooping cough has become an epidemic in California, according to a report released by the California Department of Public Health. Researchers found that cases of pertussis, more commonly known as whooping cough, have increased four fold since 2009. Officials recommend vaccination to prevent the contagious illness from become more widespread.

Cancer Video: Coffee May Reduce Cancer Risk, Children at No Cancer Risk for Cell Phone Towers, US Ranked Last in Health Care Rankings Among Developed Countries

Fri, 25 Jun 2010 17:00:00 EDT

(June 25, 2010 - Insidermedicine)

From Utah - According to a report published in Cancer Epidemiology, Biomarkers & Prevention, coffee may reduce risk of cancer. Researchers conducted a meta analysis, finding that people who drank four or more cups of coffee a day had a 39% reduced risk of developing tumors.

From Oxford - Cell phone towers do not increase risk of cancer in children, according to a report published in the British Medical Journal. Researchers compared nearly 1400 childhood cancer cases to over 5500 healthy controls, finding that mothers of children with cancer did not live any close to cell phone towers than controls.

And finally, from Washington - A new report released by the Commonwealth Fund ranks the US last in healthcare performance among developed countries. Researchers analyzed performance categories including quality, equity, access, and long, healthy living among developed nations. Results had the US ranking last among the 13 countries, with the Netherlands finishing first.

Diabetes Video: Stroke and Heart Attack Risk for Diabetics, Heavy Trans Fats and Fructose Diet Linked With Liver Disease, Whooping Cough Epidemic in California

Thu, 24 Jun 2010 19:00:00 EDT

(June 24, 2010 - Insidermedicine)

From Cambridge - According to a report published in The Lancet, diabetes dramatically raises risk of cardiovascular events. Researchers studied 700,000 people for 10 years, finding that diabetics were at 2x increased risk of suffering a stroke or heart attack.

From Cincinnati - Too much trans fats and fructose leads to liver disease, according to a report published in the journal Hepatology. Researchers gave mice a normal lean diet as well as a diet high in trans fats and fructose. Results showed that mice on the high calorie diets became obese and also developed fatty liver disease.

And finally, from California - Whooping cough has become an epidemic in California, according to a report released by the California Department of Public Health. Researchers found that cases of pertussis, more commonly known as whooping cough, have increased four fold since 2009. Officials recommend vaccination to prevent the contagious illness from become more widespread.

Flu Video: Vaccination Increases Attributed to Media Coverage, Researchers Harness Estrogen Benefits Sans Cancer Risk, Aggressive and Early Treatment Best for Arthritis

Wed, 23 Jun 2010 19:00:00 EDT

(June 23, 2010 - Insidermedicine)

From Rochester - Recent increases in vaccination rates may be because of media coverage, according to a report published in Health Service Research. Researchers reviewed data on 22 million individuals over 65 through three flu seasons . They found that national news reports covering flu related topics increased vaccination rates by as much as 8%.

From Dallas - According to a report published in the Journal of Clinical Investigation, scientists have discovered a way to harness the cardiovascular benefits of estrogen without also increasing risk of cancer. Researchers studied mice with high cholesterol and damaged carotid arteries. They found that injecting mice with an estrogen receptor molecule resulted in clear and unobstructed arteries, without adverse cancer risk.

And finally, from Finland - A new report published in Arthritis Research & Therapy recommends treating aggressive and early treatment for arthritis. Studying almost 200 patients with rheumatoid arthritis for 11 years, researchers found that those treated with a combination of disease modifying anti-rheumatic drugs (DMARDS) at the first sign of RA fared significantly better than those who received only a single DMARD.

Diabetes Video: Liver Disease Risk for New Diabetics, Alcohol Reduces Risk of Joint Diseases, Work Hour Limitations for Residents May Have Negative Effects

Tue, 22 Jun 2010 17:00:00 EDT

(June 22, 2010 - Insidermedicine)

From Toronto - According to a report published in the Canadian Medical Association Journal, newly diagnosed diabetics are at raised risk of liver disease. Researchers studied nearly 2,500,000 adults for 13 years, finding that those who were newly diagnosed with diabetes were more likely than non-diabetic adults to develop serious liver disease.

From Italy - According to a report presented at the Endocrine Society's annual meeting, alcohol consumption may lower risk of joint diseases. Researchers studied nearly 7,000 adults, finding that drinking alcohol lowered risk of joint diseases such as osteoarthritis by 73%.

And finally, from Switzerland - Work hour limits for residents may negatively affect their training and patient care, according to a report published in the Archives of Surgery. Researchers surveyed over 400 physicians following a new Swiss law implementing 50 hour workweeks for residents. Results showed that 63% of residents believed that the new law negatively affected surgical training, and 43% perceived a negative effect on patient care.

Heart Disease Video: Early Menopause Connected to Cardiovascular Events, Newborn Bacteria Dependent on Type of Birth, Some Obese People Not At Raised Risk of Heart Disease

Mon, 21 Jun 2010 17:00:00 EDT

June 21, 2010 - Insidermedicine)

From San Diego - According to a report presented at the Endocrine Society's annual meeting, women who go through menopause early are at increased risk of cardiovascular disease. Researchers studied over 2500 women, finding that those who experienced menopause before the age of 46 were more likely to suffer a heart disease event such as heart attack or stroke.

From Puerto Rico - Babies carry different bacteria depending on how they are born, according to a report published the Proceedings of the National Academy of Sciences. Researchers studied nine mothers and 10 newborns, finding that babies born by Caesarian section carried different bacterial communities than babies born vaginally.

And finally, from San Diego - A small portion of obese people are not at increased risk of heart disease, according to a report presented at the Endocrine Society's annual meeting. Studying over 1300 obese people, researchers identified just 7% of whom who were metabolically healthy. Of this 7%, only 1% developed cardiovascular disease.

Antiretroviral Video: AIDS Meds in Breastfeeding Moms Prevent HIV Transmission to Infants, Blood Pressure Med Linked to Cancer, Painkiller Abuse Rampant (Week in Review)

Sun, 20 Jun 2010 17:00:00 EDT

(June 20, 2010 - Insidermedicine)

From Ohio - According to a report published in The Lancet Oncology, a certain type of blood pressure medication may increase risk of cancer. Researchers conducted a meta analysis covering over 60,000 patients taking either angiotensin receptor blockers or a control medication. Results showed that using the ARBs increased risk of new cancers by up to 11% , while raising risk of lung cancer by 25%.

And finally, from Atlanta - A new report released by the CDC urges immediate action regarding recent increase in painkiller abuse. Researchers found that emergency department visits for painkiller abuse rose by 111% from 2004 to 2008. The authors suggest that this increase has put added strain on the health care system, so much so that hospitalizations for abuse now equal hospitalizations for illicit drugs.

Painkillers Video: Mediterranean Diet Improves Heart Function, Painkiller Abuse An Increasing Problem, Drinking Tea May Be Connected to Rheumatoid Arthritis

Sat, 19 Jun 2010 17:00:00 EDT

(June 19, 2010 - Insidermedicine)

From Indiana - According to a report published in the journal Circulation: Cardiovascular Quality Outcomes, the mediterranean diet may reduce risk of cardiac death. Researchers studied the mediterranean diet on twins, finding that the diet was associated with improvements in heart function, specifically in the frequency and timing of heart rate variability.

From Atlanta- A new report released by the CDC urges immediate action regarding recent increase in painkiller abuse. Researchers found that emergency department visits for painkiller abuse rose by 111% from 2004 to 2008. The authors suggest that this increase has put added strain on the health care system, so much so that hospitalizations for abuse now equal hospitalizations for illicit drugs.

And finally, from Italy - Too much tea may increase risk of rheumatoid arthritis in women, according to a report presented at the Annual Congress of the European League Against Rheumatism. Researchers studied over 76,000 women, finding that drinking any amount of tea was associated with a significant risk for RA--the risk increasing for those who drank four or more cups a day.

HIV Video: AIDS Meds Reduce HIV Transmission Risk for Breastfeeding Mothers, Preventing Fetal Alcohol Syndrome, H1N1 Shot Also Protects Against 1918 Spanish Flu

Wed, 16 Jun 2010 17:00:00 EDT

(June 16, 2010 - Insidermedicine)

From Boston - AIDS medications given to pregnant or breast-feeding women blocks HIV transmission to the child, according to a report published in the New England Journal of Medicine. Researchers studied over 700 HIV infected pregnant women, finding that antiretroviral drug combinations prevented HIV transmission to the infant 99% of the time.

From Washington - A new report published in the journal Developmental Neuroscience discusses the problems of preventing fetal alcohol syndrome. Researchers reviewed several studies covering FAS, finding significant links between FAS and mental retardation, but very little progress has been made in scientifically and clinically preventing the condition.

And finally, from New York - According to a report published in the journal Nature Communications, the H1N1 vaccine also protects against the 1918 Spanish influenza virus. Researchers gave mice the H1N1 vaccine, seasonal flu vaccine or no vaccine, later exposing them to the Spanish flu. They found that only mice given the H1N1 shot survived the Spanish flu virus.

Pyloric Stenosis Video: Oxygen May Be Harmful for Heart Attack Patients, Pyloric Stenosis Genetic Links, MRSA Shortens CF Survival

Tue, 15 Jun 2010 19:00:00 EDT

(June 15, 2010 - Insidermedicine)

From the UK – A new report published in The Cochrane Library questions the practice of giving heart attack patients oxygen. Researchers reviewed nearly 400 heart attack cases in which patients were given either pure oxygen or air. Overall, 14 patients died—and results showed that patients who inhaled oxygen instead of air were more likely to die.

From Denmark – A digestive disorder found in infants known as pyloric stenosis may be genetic, according to a report published in the Journal of the American Medical Association. Researchers studied data on nearly 2,000,000 children, finding that monozygotic twins had an almost 200x increased risk of the condition while siblings had a 20x increased risk.

And finally, from Cleveland – MRSA in cystic fibrosis patients is associated with considerably shorter survival, according to a report published in the Journal of the American Medical Association. Researchers studied nearly 20000 CF patients, finding that the presence of MRSA in the respiratory tract of patients was associated with a 1.3x increased risk of death.

Angiotensin Receptor Blockers Video: Healthy Diet Reduces Cataract Risk in Women, Common Blood Pressure Meds Linked to Cancer, AMD Risk and Lifestyle Factors

Mon, 14 Jun 2010 17:00:00 EDT

(June 14, 2010 - Insidermedicine)

From Wisconsin - Women who eat healthy may have reduced risk of cataracts, according to a report published in the Archives of Ophthalmology. Studying over 1800 women, researchers found that eating more than recommended levels of fruits, vegetables, grains, milk, meat and healthy sources of protein while ensuring lower than recommended levels of saturated fat, cholesterol and sodium resulted in a lower risk of developing cataracts.

From Ohio - According to a report published in The Lancet Oncology, a certain type of blood pressure medication may increase risk of cancer. Researchers conducted a meta analysis covering over 60,000 patients taking either angiotensin receptor blockers or a control medication. Results showed that using the ARBs increased risk of new cancers by up to 11% , while raising risk of lung cancer by 25%.

And finally, back to Wisconsin - According to another report published in the Archives of Ophthalmology, early stage age related macular degeneration may be influenced by modifiable risk factors. Researchers studied over 2800 adults, finding that lifestyle factors such as smoking and cholesterol raised risk of developing AMD.

Cancer Video: Bevacizumab Raises Kidney Damage Risk, No Survival Benefit with Axillary Node Dissection, Sleep Deprived Nurses

Fri, 11 Jun 2010 19:00:00 EDT

(June 11, 2010 - Insidermedicine)

From New York - The cancer drug bevacizumab increases risk of kidney damage, according to a report published in the Journal of the American Society Nephrology. Researchers conducted a meta analysis covering over 12,000 cancer patients, finding that patients taking bevacizumab plus chemotherapy had nearly 5x increased risk of developing proteinuria.

From Chicago - According to a report presented at the meeting for the American Society of Clinical Oncology, axillary node dissection in breast cancer patients offers no survival benefit. Researchers studied over 800 breast cancer patients, finding that removing the axillary nodes in those with affected lymph nodes did not noticeably reduce risk of relapse or death from the disease.

And finally, from Illinois - A new report presented at the meeting of the Associated Professional Sleep Societies outlines problems that arise when nurses are sleep deprived. Studying 80 nurses working three successive 12 hours shifts, researchers found that 39% of nurses had moderate lapses of attention during their shifts, while 7% had frequent lapses.

Allopurinol Video: Genetic Mutation Linked to Alzheimer's, Allopurinol Beneficial for Kidney Disease Patients, Insomnia and Risk of Death

Thu, 10 Jun 2010 17:00:00 EDT

(June 10, 2010 - Insidermedicine)

From New York - According to a report published in the journal Cell, researchers have identified a genetic mutation may cause Alzheimer's disease. Studying mice with Alzheimer's, researchers found that mutations in the rodent's presenilin gene killed nerve cells and promoted the development of early onset Alzheimer's--a process that occurred independently of amyloid beta.

From Spain - A drug used to treat gout significantly benefits kidney disease patients, according to a report published Clinical Journal of the American Society of Nephrology . Researchers randomized over 100 chronic kidney disease patients to continue their normal therapy or to receive the gout medication allopurinol. Results showed that the allopurinol group had 71% reduced risk of cardiovascular events.

And finally, from San Antonio - According to a report presented at the meeting of the Associated Professional Sleep Societies, insomnia significantly raises ones risk of death. Researchers studied over 2000 adults for 19 years, finding that participants suffering from chronic insomnia had 3x increased risk of death.

Autism Video: Genes Related to Autism Susceptibility Found, Genetic Variant Responsible for Vitamin D Insufficiency, Sleep Problems Common for War Vets

Wed, 9 Jun 2010 19:00:00 EDT

(June 9, 2010 - Insidermedicine)

From New York - According to a report published in the journal Nature, scientists have identified a host of genes related to autism susceptibility. Studying 1000 people with autism and 1300 without, researchers found a series of extremely rare genetic variants that were associated with susceptibility to autism spectrum disorder.

From London - Vitamin D insufficiency may be influenced by genetic factors, according to a report published in The Lancet. Researchers studied nearly 34,000 caucasians of European descent, finding that individuals with three specific genetic variants had 2.5x increased risk of vitamin D insufficiency.

And finally, Illinois - US soldiers returning from deployment commonly suffer sleep problems, according to a report presented at the meeting of the Associated Professional Sleep Societies. Researchers studied nearly 60 soldiers following their return from deployment, finding that 86% suffered sleep problems upon their return.

Heart Disease Video: Height Linked to Heart Disease Risk, Possible Connection Between Diabetes and Schizophrenia, Children of Abused Mothers More Likely to Be Obese

Tue, 8 Jun 2010 19:15:00 EDT

(June 8, 2010 - Insidermedicine)

From Finland - According to a report published in the European Heart Journal, height may be connected to heart disease risk. Researchers reviewed over 50 studies covering over 3,000,000 patients, finding that short women (below 153 cm) and short men (below 165 cm) had nearly 1.5 fold increased risk of dying from heart disease.

From Tennessee - Scientists may found a connection between diabetes and schizophrenia, according to a report published in PLoS Biology. Researchers studied mice with a defect in their insulin action--a defect commonly found in diabetics. They found that the rodents consequently had reduced dopamine in their brains and developed behavioral problems similar to those seen in schizophrenic patients.

And finally, from Boston - Children of abused mothers are at increased risk of obesity according to a report published in the Archives of Pediatrics and Adolescent Medicine. Researchers studied over 1500 children, finding that children of mothers who reported being chronically abused by their partner had 1.8x increased risk of being obese by age 5.

PTSD Video: Smoke Laws Effectively Reduce Secondhand Smoke, HPV Main Predictor of Survival in Throat Cancer Patients, PTSD Raises Risk of Dementia in Veterans

Mon, 7 Jun 2010 17:00:00 EDT

(June 7, 2010 - Insidermedicine)

From Boston – According to a report published in the journal Pediatrics, smoke free air laws appear to protect children from secondhand smoke. Researchers studied cotinine levels in nearly 12,000 non smoking children, finding that those living in areas that had laws promoting smoke free public places had 39% less cotinine in their blood.

From Ohio – The presence of HPV in tumors is the most important predictor of throat cancer survival, according to a report published in the New England Journal of Medicine. Researchers studied over 300 throat cancer cases, finding that after three years of treatment, 82% of patients with HPV in their tumors were still alive, compared with only 57% of patients whose tumors did not have the virus.

And finally, from California – According to a report published in the Archives of General Psychiatry, older veterans who suffer PTSD are also at increased risk of dementia. Studying over 180,000 veterans over 55 years old, researchers found that veterans with PTSD were at 11% increased risk of also developing dementia.

Medical Errors Video: Residents' Mistakes Harmful, Olive Oil Diet Helps Breast Cancer Survivors Shed Weight, Special Alzheimer's Care Plans Do Not Slow Disease Progression

Fri, 4 Jun 2010 17:00:00 EDT

(June 4, 2010 - Insidermedicine)

From San Diego - A new report published in the Journal of General Internal Medicine links deadly medical errors to July--the month when residents begin work. Researchers reviewed death certificates over a 27 year period, finding that fatal medication errors rose by 10% in July in counties with a teaching hospital. This association was not found in any other month.

From Providence - According to a report published in the Journal of Women's Health, an olive oil based diet can help breast cancer survivors lose weight. Researchers compared a low fat diet with an olive oil enriched diet on 44 overweight breast cancer survivors. Results showed that 80% of the women on the olive oil diet lost over 5% of their weight, compared with only 31% on the low fat diet.

And finally, from France - Special care plans for Alzheimer's patients do not appear to slow progression of their disease, according to a report published in the British Medical Journal. Researchers studied over 1100 Alzheimer's patients, randomizing participants to either usual care or a special dementia care plan. After two years, researchers found no significant difference in functional decline between the two groups.

Down Syndrome Video: Beta Amyloid Reduction Improves Down Syndrome in Mice, Mediterranean Diet Lowers Child's Risk of Asthma, Chocolate Milk Best Post Exercise Drink

Thu, 3 Jun 2010 19:00:00 EDT

(June 3, 2010 - Insidermedicine)

From Texas - According to a report published in PLoS One, reducing beta amyloid in mice with Down syndrome improves their learning ability. Researchers studied mice with a condition that closely resembles Down syndrome in humans, finding that reducing beta amyloid production by 40% resulted in the rodents being able to navigate a maze as quickly as normal mice.

From Germany - A child's diet is connected to their risk of asthma, according to a report published in the journal Thorax. Researchers conducted a meta analysis covering over 50,000 children, finding that eating a mediterranean diet significantly lowered the child's risk of wheezing and asthma.

And finally, from Baltimore - A new report presented at the American College of Sports Medicine meeting outlines the benefits of drinking chocolate milk after exercise. Researchers studied the two hour window following exercise, finding that low fat chocolate milk outperformed several sports drinks in rebuilding and retaining muscle, as well as prepping the body for more exercise.

Aspirin Video: Size of Prostate Tumor Linked To Patient Weight, Quitting Smoking Beneficial for Fracture Surgery Patients, New Recommendations for Aspirin Use in Diabetics

Wed, 2 Jun 2010 17:00:00 EDT

(June 2, 2010 - Insidermedicine)

From Detroit – According to a report presented at the American Urological Association meeting, the size of prostate cancer tumors is directly linked to the weight of the patient. Researchers studied over 3300 prostate cancer patients, finding that the higher the patient's BMI, the larger the tumor.

From Sweden – Smokers who quit after undergoing fracture surgery heal better than those who continue to smoke, according to a report published in The Journal of Bone and Joint Surgery. Researchers enrolled a group of smokers who underwent fracture surgery in a postoperative smoking cessation program. They found that the intervention program reduced postoperative complications by nearly 50%.

And finally, from Oregon – A new report published in Diabetes Care outlines new recommendations for use of aspirin to prevent heart attacks. Researchers reviewed nine studies, finding that men under 50 and women under 60 who have diabetes should not use low dose aspirin therapy because the potential harm outweighs the potential benefits. These results were supported by the American Diabetes Association, the American Heart Association and the American College of Cardiology.

Lung Cancer Video: Rising Lung Cancer Rates in Non Smoking Women, Hospital Death Rates Decline for Heart Failure Patients, Drunk Driving Worst at 21 Years Old

Tue, 1 Jun 2010 17:00:00 EDT

(June 1, 2010 - Insidermedicine)

From Philadelphia - According to a report published in Cancer Prevention Research, scientists may have found a reason for rising lung cancer rates in non smoking women. Researchers studied the effects of smoke exposure on mice, finding that smoke altered the expression of genes involved in estrogen metabolism which in turn affect cancer formation and progression--an aspect researchers believe may explain the rising incidence of lung cancer in non-smoking women.

From Spain - Though in hospital mortality rates have decline in heart failure patients, readmission rates have increased, according to a report published in the Journal of the American Medical Association. Researchers reviewed data on heart failure patients from 1993-2006. They found that average hospital stay decreased by two days, in hospital mortality decreased by nearly 50%, and 30 day readmission rates increased by nearly 3%.

And finally, from Maryland - According to a report published in Alcoholism: Clinical & Experimental Research, drinking and driving becomes a bigger problem for college students after they turn 21. Researchers followed over 1200 students through four years of college, finding noticeable increases in drinking and driving, riding along with a drunk driver and driving after having any alcohol when students reached 21 years of age.

VIDEO: Breast Cancer Vaccine Possible, Acupuncture at the Molecular Level, Nocturia Increases Risk of Death

Mon, 31 May 2010 17:00:00 EDT

(May 31, 2010 - Insidermedicine)

From Cleveland - Breast cancer vaccination may be possible, according to a report published in the journal Nature Medicine. Researchers gave an experimental vaccine to mice genetically engineered to be at high risk for breast cancer. They found that mice not given the vaccine developed tumors but those given the vaccine did not.

From Rochester - A new report published in the journal Nature Neuroscience outlines how acupuncture works at the molecular level. Researchers gave mice acupuncture to examine the role of adenosine--a natural compound that acts as a painkiller. They found that mice with normal levels of this compound reduced their discomfort by two thirds with acupuncture, and that during and after treatment, the amount of adenosine in the area around the needles increased by 24x.

And finally, from San Francisco - Waking up multiple times in the night to urinate significantly increases ones risk of death, according to a report presented at the American Urological Association meeting. Researchers studied data on nearly 16,000 adult men and women, finding that waking up to urinate two or more times in the night--a condition known as nocturia--resulted in a 50% increased risk of death for men and 30% increased risk for women.

TRANS FAT VIDEO: Ultrasound Detects Stroke Risk in Asymptomatic Carotid Stenosis Patients, Trans Fats Declining in Restaurants and Markets, Heart Risk of Poor Oral Hygiene

Fri, 28 May 2010 17:00:00 EDT

(May 28, 2010 - Insidermedicine)

From London - According to a report published in the Lancet Neurology, ultrasound can detect which asymptomatic carotid stenosis patients are at high risk of stroke. Researchers used an ultrasound procedure to stud y nearly 500 carotid stenosis patients with no symptoms, finding that patients with embolic signals had 2x increased risk of stroke.

From Boston - According to a report published in the New England Journal of Medicine, more and more food manufacturers are replacing trans fats with healthier fats. Researchers studied 83 brand name foods that, prior to 2007, were made with trans fat. Results showed that overall, both trans and saturated fats were reduced by 96% in restaurants, and 90% in supermarket foods.

And finally, back to London - A new report published online in the British Medical Journal outlines the health risks of bad oral hygiene. Researchers studied over 11,000 adults. After adjusting for factors such as obesity and smoking, results showed that those who reported poor oral hygiene had 70% increased risk of heart disease when compared to those who brushed their teeth twice a day.

DIALYSIS VIDEO: Reducing Salt Intake in Dialysis Patients, Mental Illness Linked To Immune System Defect in Mice, Rheumatoid Arthritis Increasing in Women

Thu, 27 May 2010 17:00:00 EDT

(May 27, 2010 - Insidermedicine)

From Indiana - Dialysis patients benefit more from reduced salt intake than antihypertensive medications, according to a report published in the Clinical Journal of the American Society Nephrology. Researchers examined blood pressure control in dialysis patients, finding that reducing fluid buildup in the blood by restricting salt consumption was better for the patient's hearts than taking antihypertensive medications.

From Utah - Scientists have discovered that bone marrow transplants cured mice of compulsive grooming behavior, according to a report published in the journal Cell. Researchers first discovered that a mutant gene Hoxb8 caused mice to compulsively groom themselves by pulling out their own hair (a mental illness that affects many humans). They then discovered that transplanting bone marrow from normal mice cured the affected mice of this behavior. This study is the first to connect an immune system defect to mental illness.

And finally, from Minnesota - Rheumatoid arthritis is increasing in women, according to a report published in the journal Arthritis & Rheumatism. Researchers found that from 1997-2005, RA increased in women by 2.5% per year. Environmental factors--such as lack of vitamin D, smoking, and lower amounts of estrogen in oral contraceptives--may be to blame.

HIV VIDEO: Antiretroviral Therapy Reduces Risk of HIV Transmission Between Partners, Congenital Heart Defect Gene Discovered, HDL Cholesterol Poses Risks For Certain People

Wed, 26 May 2010 20:00:00 EDT

(May 26, 2010 - Insidermedicine)

From Washington - Antiretroviral therapy in HIV patients dramatically reduces risk of transmission to their partners, according to a report published in The Lancet. Researchers studied over 3400 heterosexual couples in which one partner had HIV. Results showed that those treated with antiretroviral therapy had a reduced risk of transmitting the disease to their partners by 92%.

From Philadelphia - According to a report published in PLoS ONE, scientists have found the first gene linked to congenital heart disease. Researchers compared the blood of 300 children with congenital heart disease to DNA samples from 2200 healthy children. They found a genetic variant on chromosome 5 known as ISL1 associated with increased risk of CHD.

And finally, from Rochester - According to a report published in the journal Arteriosclerosis, Thrombosis, and Vascular Biology, HDL--or, good cholesterol carries health risks for some people. Researchers studied nearly 800 patients with elevated C-reactive protein levels, finding that elevated HDL cholesterol raised their risk of coronary events such as heart attack and death.
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BLOOD PRESSURE VIDEO: Bacteria Predictive of Colorectal Cancer, Blood Pressure Control and Prevalence in US, Folic Acid Prevents Alcohol Heart Defects in Pregnant Mice

Tue, 25 May 2010 17:00:00 EDT

(May 25, 2010 - Insidermedicine)

From San Diego - According to a report presented at the annual meeting of the American Society for Microbiology, scientists have identified a bacteria that may predict colorectal cancer. Researchers examined 91 people, several of whom had at least one polyp. They found certain bacterial signatures only in the intestinal tract of those with a polyp.

From South Carolina - While high blood pressure is now controlled better in the US, its prevalence is not decreasing, according to a report published in the Journal of the American Medical Association. Researchers found that from 1988 to 2008, high blood pressure control increased from 27% to 50% . However, prevalence of the condition did not decrease during the same time period and hypertension rates remain high.

And finally, from Florida - According to a report published in the American Journal of Obstetrics and Gynecology, folic acid in pregnant mice prevented alcohol induced heart defects. Researchers gave mice a high dose of folic acid in early pregnancy, and then administered enough alcohol in the mice to simulate binge drinking in humans. Results showed that administering the high folate dose prior to alcohol exposure protected heart valve development and brought heart function to near normal levels.

SMOKING VIDEO: Smoking Cessation Effective for Mental Illness Patients, Exercise Good for Cancer Patients, Importance of Kidney Weight in Transplantation

Fri, 21 May 2010 17:00:00 EDT

(May 21, 2010 - Insidermedicine)

From the UK - According to a report published in the journal Addiction, treating smoking dependence in severe mental illness patients is both effective and safe. Researchers studied smoking cessation treatments on people with SMIs such as schizophrenia, finding that patients responded to both pharmaceutical and behavioral therapy with no adverse effects on their mental health.

From Detroit - Cancer patients are healthier during and after treatment if they exercise, according to a report presented at the American Society of Clinical Oncology meeting. Researchers studied 30 breast cancer patients and 20 prostate cancer patients, finding that regular exercise improved fatigue and led to an overall better quality of life.

And finally, from France - A new report published in the Journal of the American Society of Nephrology outlines the importance of kidney weight in kidney transplantation. Researchers followed nearly 200 patients for several years following kidney transplantation. They found that receiving a kidney low in weight in relation to the patients body weight resulted in a greater risk of complications and transplant failure.

STROKE VIDEO: Racial Disparity Among Blood Clot Related Strokes, Pistachios Good For Health, Fast Inexpensive DNA Sequencing Technology

Thu, 20 May 2010 19:00:00 EDT

(May 20, 2010 - Insidermedicine)

From Cincinnati - A new report published in Stroke: Journal of the American Heart Association reveals racial disparity in the amount of blood clot related strokes. Researchers studied data on 1.3 million people, finding a 14% reduction in blood clot related strokes among Caucasians but a 5% rise in African Americans.

From Pennsylvania - According to a report published in the Journal of Nutrition, pistachios can be included in a healthy diet. Researchers added pistachios to a heart healthy moderate fat diet, finding that participants on the pistachio diet had raised antioxidants that helped to lower bad cholesterol.

And finally, from Boston - Development of inexpensive and fast DNA sequencing is bringing the technique closer to clinical use, according to a report published in the journal Nano Letters. For the first time, researchers have used nanopores to sequence each DNA molecule. As a result, scientists are able to precisely analyze long DNA molecules at low cost and ultra fast speed.

POSTPARTUM DEPRESSION VIDEO: Processed Meats Raise Risk of Heart Disease, Diabetes, Rates of TB Worldwide, Postpartum Depression For Dads

Tue, 18 May 2010 19:00:00 EDT

(May 18, 2010 - Insidermedicine)

From Boston - According to a report published in the journal Circulation, processed meats may raise risk of heart disease and diabetes. Researchers reviewed almost 1,600 studies, finding that consumption of meats such as bacon, sausage and processed lunch meats increased risk of heart disease by 42% and diabetes by 19%. This association however was not found in unprocessed red meats such as lamb, beef or pork.

From Switzerland - A new report published in The Lancet outlines the improvements made in rates of tuberculosis (TB). Between 1995 and 2008, researchers found that 36 million people were cured from TB. However, TB remains a problem for the world's poorest people, killing nearly 2 million people yearly.

And finally, from Virginia - A significant amount of men also experience prenatal and postpartum depression, according to a report published in the Journal of the American Medical Association. Researchers reviewed over 40 studies covering 28,000 participants, finding that 10% of men overall experienced paternal depression, with 26% experiencing depression between the 3-6 month postpartum period.

NON HODGKIN LYMPHOMA VIDEO: Lifestyle Factors and Risk of Death in NHL Patients, Cheese Good For Elderly Immune System, HIV Progresses Faster With Alcohol Consumption

Fri, 14 May 2010 17:00:00 EDT

(May 14, 2010 - Insidermedicine)

From Minnesota - Survival of non-Hodgkins lymphoma patients can be influenced greatly by lifestyle factors, according to a report published in the journal Cancer. Researchers studied data on over 1,200 non-Hodgkins lymphoma patients, finding that those with a 20 year history of smoking were at 76% increased risk of death, those who drank over 43 grams of alcohol a week had a 55% increased risk, and obese NHL patients were at 32% increased risk.

From Finland - According to a report published in FEMS Immunology & Medical Microbiology, elderly people may be able to boost their immune system by eating cheese. Researchers gave a group of elderly patients either placebo or probiotic Gouda cheese. Results showed that the Gouda group had enhanced immunity because the cheese acted as a carrier for probiotic bacteria and helped to activate participant's NK blood cells.

And finally, from New York - HIV patients will see their disease progress faster with frequent alcohol use, according to a report published in AIDS Research and Human Retroviruses. Researchers conducted a retrospective study, finding that two or more alcoholic drinks a day resulted in declining CD4 cell counts.

ATRIAL FIBRILLATION VIDEO: Ablation Reduces Risk of Alzheimer's, Stroke and Death, Few Call 911 at Signs of Stroke, Benefits of Breastfeeding

Thu, 13 May 2010 17:30:00 EDT

(May 13, 2010 - Insidermedicine)

From Utah - According to a report presented at the National Heart Rhythm Society Sessions, a common heart procedure used to treat atrial fibrillation also lowers risk of several other conditions. Researchers studied atrial fibrillation patients, finding that the procedure--known as catheter ablation--significantly reduced risk of Alzheimer's disease, stroke and death.

From Michigan - Too many people would not phone 911 when they see stroke symptoms in a friend or family member, according to a report published in Stroke: Journal of the American Heart Association. Researchers surveyed nearly 5000 adults, finding that only 14% would call 911 when 3 common stroke symptoms were present, and that 37% would not call for any of the stroke signs.

And finally, from Illinois - A new report published in the American Journal of Physiology, Gastrointestinal and Liver Physiology outlines why breast milk is so beneficial. Researchers studied 12 breast fed and 10 formula fed babies, finding that breast milk influenced certain genes in the intestinal tract that formula did not. The breast fed babies guts were more able to recognize bad bacteria and able to fight it off, an aspect that could reduce their risk of food allergies, asthma and inflammatory bowel disease.

VITAMIN A VIDEO: Maternal Vitamin A Improves Infant Lung Function, Distracted Doctors Do Not Finish Tasks, Sweets Decrease Baby Immunization Pain

Wed, 12 May 2010 19:00:00 EDT

(May 12, 2010 - Insidermedicine)

From Baltimore - According to a report published in the New England Journal of Medicine, vitamin A supplementation in mothers increases lung function in their children. Researchers gave a group of mothers vitamin A supplementation or placebo before, during and after pregnancy. Results showed that the children of the vitamin A group had significantly improved lung function.

From Australia - Doctors interrupted while working spend less time on tasks and frequently fail to return what they were doing, according to a report published in the journal Quality and Safety in Health Care. Studying 40 doctors in one teaching hospital, researchers found that when the doctors were interrupted, they spent about half the time they normally would on a task, and one fifth of the time they would fail to return to the task at hand.

And finally, from Toronto - According to a report published in the Archives of Disease in Childhood, giving infants sweet solutions prior to immunization reduces pain. Researchers reviewed 14 studies covering over 1600 injections. In 13 of the studies, results showed that giving a child a solution of sucrose and glucose before injection reduced pain and decreased crying.

CAFFEINE VIDEO: Overtime Increases Heart Disease Risk, Sickle Cell May Affect Brain, Caffeine Good For Shift Workers

Tue, 11 May 2010 19:00:00 EDT

(May 11, 2010 - Insidermedicine)

From London – According to a report published in the European Heart Journal, working overtime may increase risk of heart disease. Researchers studied over 10,000 people, finding that those who worked 3 or more hours than a regular seven hour day had a 60% increased risk of developing heart disease, and suffering non fatal heart attacks and angina.
From California – Sickle cell disease may also affect brain functioning, according to a report published in the Journal of the American Medical Association. Researchers compared nearly 150 sickle cell patients to 47 healthy controls, finding that the sickle cell group scored lower on tests gauging working memory, attention, processing speed and intellectual ability.
And finally, back to London – According to a report published in the Cochrane Library, caffeine can help shift workers reduce their mistakes. Reviewing over 13 trials, researchers found that caffeine outperformed placebo or naps in reducing errors, and also improved memory, attention and reasoning scores on neuropsychological tests.

RESTLESS LEG VIDEO: Restless Leg Syndrome Runs In Families, Meat May Be Contaminated By Listeria, Proton Pump Inhibitors Associated With Fractures and Infections

Mon, 10 May 2010 19:00:00 EDT

(May 10, 2010 - Insidermedicine)

From Chicago - Restless leg syndrome appears to run in families according to a report published in the May issue of Archives of Neurology. Researchers studied 671 patients and found that siblings of an individual with restless leg syndrome were 3.6 times as likely to have the condition, while children of parents with restless leg syndrome were 1.8 times as likely to have it develop. This aggregation of the condition in families could be due to genetic influences, environmental factors, or a combination of both.

From Ottawa - Meat products produced by Zadi Foods Ltd. may be contaminated with listeria, according to a warning released by the Canadian Food Inspection Agency. While eating food contaminated with listeria may not appear spoiled, it can lead to high fever, severe headache, neck stiffness and nausea, particularly among pregnant women, the elderly and people with weakened immune systems. So far, no illnesses associated with the consumption of products has been reported.

From Chicago - Proton pump inhibitors appear to be associated with fractures in postmenopausal women and bacterial infections in many patients, according to a series of reports in the May 10 issue of Archives of Internal Medicine. Researchers found an increased risk of spine and forearm fractures in women between the ages of 50 and 79. Daily use of proton pump inhibitors were also associated with an estimated 74 percent increase in infection with Clostridium difficile.

CHOLESTEROL VIDEO: Eating Nuts Can Help Improve Cholesterol Levels

Mon, 10 May 2010 19:00:00 EDT

(May 10, 2010 - Insidermedicine)

Eating nuts every day can help improve cholesterol levels, according to research published in the May 10 issue of the Archives of Internal Medicine.

Some ways to help you improve your cholesterol levels include:

•    Getting regular exercise

•    Maintaining or attaining a healthy weight

•    Making sure most of the fat you eat is from vegetables, nuts, and fish and not from meat or dairy

Researchers from Loma Linda University in Loma Linda analyzed data collected from 25 studies looking at the effects of eating nuts on cholesterol levels. The studies involved nearly 600 individuals who had either normal or high cholesterol levels but who were not taking cholesterol-lowering drugs,

Eating an average of 67 grams, or 2.4 ounces, of nuts every day was associated with an average 5.1% reduction in total cholesterol, a or “bad” cholesterol, 8.3% reduction in the ratio of LDL to HDL or “good” cholesterol , and 5.6% reduction in the ratio of total to HDL cholesterol. Triglycerides were also reduced by an average of 10.2%, but only among those whose triglyceride levels were high to begin with. The more nuts eaten, the greater the effects on cholesterol levels, and all types of nuts appeared to have similar effects. Eating nuts had the greatest effects on cholesterol levels among those with high LDL cholesterol, a low body mass index (BMI), and a typical Western diet.

Today’s research suggests that adding nuts to one’s diet could help improve cholesterol levels.

SLEEP VIDEO: Elderly People Struggle to Get Sleep, Stem Cells can Provide Lasting Help to Injured Hearts, CT Scans Superior to X-Rays

Fri, 7 May 2010 20:40:00 EDT

(May 7, 2010 - Insidermedicine)

From California - According to a study published by the American Geriatrics Society, elderly people in assisted living facilities struggle to get a full night's sleep. The study showed that 65% of assisted living facility residents had clinically significant sleep problems and that poor sleep was associated with declining quality of life and increased depression.

From Texas - According to a study to be published in Circulation Research, transplanted human adult stem cells can provide lasting help to injured hearts. Scientists injected human adult stem cells into mouse models, and found improved pumping efficiency for a year following the injection. This improvement was caused by increased blood vessel formation in and around the injured area.

From Pittsburgh - According to a study presented at the American Roentgen Ray Society 2010 Annual Meeting, CT scans are superior to standard X-rays for the detection of pelvic fractures. The study included 132 patients with pelvic fractures and found that X-rays failed to identify 48 percent of pelvic injuries. While most orthopedic surgeons will order additional X-ray views after a CT scan, the study now recommends eliminating this step.

BREAST CANCER VIDEO: Breast Cancer Correlated to Circulating Tumor Cells, Screenings for Spinal Muscular Atrophy, Dark Chocolate May Protect Brain After a Stroke

Thu, 6 May 2010 19:00:00 EDT

(May 6, 2010 - Insidermedicine)

From Belgium - According to a report presented at the IMPAKT Breast Cancer Conference, survival from metastatic breast cancer is directly correlated to the amount of circulating tumor cells patients have in their blood. Researchers analyzed over 500 metastatic breast cancer patients, finding that 40 circulating tumor cells in 7.5 ml of blood raised ones risk of death at one year two fold.

From Ohio - Technology has improved to the point where newborn and carrier screening for spinal muscular atrophy is now possible, according to a report published in the American Journal of Medical Genetics. Results of pilot studies were successful in screening SMA in newborns, as well as identifying parents who may be carriers the condition.

And finally, from Baltimore - According to a report published in the Journal of Cerebral Blood Flow and Metabolism, dark chocolate may protect the brain after a stroke. Researchers gave mice a single dose of dark chocolate and then induced stroke. Results showed that mice who ate the dark chocolate suffered significantly less brain damage than those who did not eat the chocolate.

DEMENTIA VIDEO: Spouses of Dementia Patients More Likely To Experience Same, Job Stress Increases Heart Disease in Women, Obese Children and Weight Loss Surgery

Wed, 5 May 2010 19:00:00 EDT

(May 5, 2010 - Insidermedicine)

From Utah - According to a report published in the Journal of the American Geriatrics Society, older adults who have a spouse with dementia are at increased risk of the developing the condition themselves. Researchers studied nearly 2500 adults over 65 for 12 years, finding that spouses of dementia sufferers were at 6x increased risk of also developing dementia.

From Denmark - Women with high pressure jobs are at increased risk of heart disease, according to a report published in the journal Occupational and Environmental Medicine. Researchers studied over 12,000 nurses, finding that those who reported their job pressure as being much too high were at almost 50% increased risk of heart disease.

And finally, from the UK - Obese children should undergo weight loss surgery only in the most extreme circumstances, according to a report published in The Lancet. Researchers assert that lifestyle interventions such as diet and exercise should be the first choice of therapy, and that surgery should only be used in children in the highest 5% of BMI with obesity related complications and who have failed to respond to lifestyle interventions.

CYSTIC FIBROSIS VIDEO: Newborn Weights Increasing, Azithromycin Does Not Improve CF Lung Function, Vitamin A Does Not Decrease Maternal, Infant Mortality

Tue, 4 May 2010 19:00:00 EDT

(May 4, 2010 - Insidermedicine)

From Kansas City – According to a report presented at the Pediatric Academic Societies meeting, an increasing amount of newborns are overweight. Researchers reviewed over 74,000 births, finding that as the BMI of pregnant mothers increased significantly from 1990 to 2005, so too did the ponderal index increase in newborns.

From New York – Treatment of children with cystic fibrosis with azithromycin does not appear to improve lung function, accord to a report published in the Journal of the American Medical Association. Researchers studied over 320 children with cystic fibrosis, randomizing participants to either azithromyzin or placebo. Results showed that the antibiotic group did experience less cough, but did not however experience improved lung function.

And finally, from Ghana – Vitamin A supplementation does not affect pregnancy related mortality, according to a report published in The Lancet. Researchers studied over 100,000 women of reproductive age, randomizing participants to once weekly vitamin A supplementation or placebo. They found that supplementation did not reduce maternal mortality or survival of the children.

BREAST CANCER VIDEO: Early Mammography Screening Not Useful, High Blood Pressure Not Detected in Children, Antidepressant Class Does Not Affect Suicide Risk

Mon, 3 May 2010 17:00:00 EDT

(May 3, 2010 - Insidermedicine)

From North Carolina - According to a report published in the Journal of the National Cancer Institute, mammography screening in younger women does not appear to detect many cancers. Researchers reviewed data on over 115,000 women who had a mammogram under the age of 40. They found that screening of women under 25 found no cancers, and that screening of women aged 35-39 had a very low cancer detection rate and resulted in many women being recalled for additional tests.

From Baltimore - A new report published in the journal Pediatrics outlines the difficulty of identifying high blood pressure in children. Analyzing the records of over 2500 pediatrics visits, researchers found that the child's blood pressure was not even checked 20% of the time, and that when checked, elevated blood pressure went unrecognized 87% of the time.

And finally, from Boston - According to a report published in the Archives of General Psychiatry, risk of suicide attempt is similar for those starting antidepressant medication, regardless of the specific class of drug. Researchers reviewed data on over 287,000 individuals on antidepressant therapy, finding no meaningful difference in the amount of suicide or suicide attempts among the several classes of antidepressant medication.

LUNG CANCER VIDEO: Accelerated Radiotherapy Course for Lung Cancer Patients, Protein in Urine and Hypertensive Patients, Cancer Risk for Post Kidney Transplant Patients

Fri, 30 Apr 2010 19:00:00 EDT

(April 30, 2010 - Insidermedicine)

From Switzerland - According to a report presented at the annual European Lung Cancer Conference, lung cancer patients may benefit from accelerated radiotherapy. Researchers conducted a meta analysis covering 10 trials and over 2200 patients with non-metastatic lung cancer. They found that accelerated radiotherapy improved survival 3% over 5 years.

From Italy - High blood pressure patients with protein in their urine at increased risk of kidney and heart problems, according to a report published in the Clinical Journal of the American Society of Nephrology. Researchers studied nearly 1000 hypertensive patients for 4 years, finding that those with protein in their urine were 7.6 x more likely to develop chronic kidney disease, and 2.1 x more likely to suffer heart disease or stroke.

And finally, from Australia - According to a report published in the Journal of the American Society of Nephrology, medications taken by post-kidney transplant patients carry the same risk of cancer. Researchers studied nearly 500 kidney transplant patients, each receiving one of three treatment options to prevent organ damage. Results showed that the risk of cancer was the same for all patients, regardless of the type of drug they were taking.

HEART DISEASE VIDEO: Enzyme Linked to Heart Disease Risk, Obesity Increases Likelihood of Fibromyalgia, Genomic Analysis to Predict Disease and Response to Drugs

Thu, 29 Apr 2010 19:00:00 EDT

(April 29, 2010 - Insidermedicine)

From Cambridge - An enzyme that is found in the blood with LDL cholesterol has been connected to heart disease, according to another report published in The Lancet. Researchers reviewed 32 studies, examining the levels of Lp-PLA2 in the blood of over 79,000 total participants. They found that increased levels of the enzyme significantly raised risk of heart disease, so much so that its effect on the heart was deemed equivalent to that of high blood pressure.

From Norway - According to a report published in Arthritis Care & Research, obesity increases risk of fibromyalgia. Researchers studied nearly 16,000 women for 11 years, finding that high BMI was an independent risk factor for fibromyalgia, and that women who exercised 4 times a week had a 29% reduced risk of developing the condition.

And finally, from Boston - Another report published in The Lancet discusses how whole genomic analysis may be used to assess a patients risk for disease and possible response to medication. Researchers examined the whole genome of a 40 year old man, revealing several specific variants of diseases within the man's family, as well as variants that predicted the man would have an atypical response to particular heart medications.

BREAST CANCER VIDEO: Invasive Breast Cancer Markers, Canadians Healthier than Americans, MS Environmental Link

Wed, 28 Apr 2010 19:00:00 EDT

(April 28, 2010 - Insidermedicine)

From San Francisco – Scientists may have discovered a method able to predict which women will develop invasive breast cancer, according to a report published in the Journal of the National Cancer Institute. Researchers reviewed over 1,100 cases of women diagnosed with ductal carcinoma in situ (DCIS)—a form of non-invasive breast cancer—who were treated with lumpectomy. They found that the manner of diagnosis as well as the expression of certain biomarkers increased risk of the DCIS turning into invasive breast cancer.

From Oregon – According to a report published in the journal Population Health Metrics, Canadians live longer and healthier lives than Americans. Using info from the Joint Canada/United States Survey of Health 2002/03, researchers found that Canadians have a higher life expectancy than Americans, despite similarities in living standards. The researchers suggest that national differences in health care and social equality are the reason for this disparity.

And finally, back to San Francisco – According to a report published in the journal Nature, scientists believe that there may be an environmental component to multiple sclerosis. Researchers studied identical twins—one with MS and the other without. In depth genomic analysis was unable to explain why one twin developed the disease and the other did not, an aspect that led the study authors to suggest there may be an environmental factor to consider.

CANCER VIDEO: Cost of Imaging Increasing For Cancer Patients, Obese Children Metabolize Medication Differently, High Dose B Vitamin Linked With Kidney Function Decline

Tue, 27 Apr 2010 17:00:00 EDT

(April 27, 2010 - Insidermedicine)

From North Carolina – According to a report published in the Journal of the American Medical Association, the cost of imaging patients with cancer has increased in the last seven years. From 1999 to 2006, researchers found that use of imaging tests such as echocardiogram, MRI, ultrasound and CT scans all increased, with positron emission tomography (PET) increasing the most. As a result, the average 2 year imaging cost per beneficiary doubled.

From California – Children who are obese metabolize medications differently than those of healthy weight, according to a report presented at the annual meeting for the American Society for Pharmacology and Experimental Therapeutics. Researchers examined both obese and healthy weight children, finding a noticeable difference in how the two groups metabolized the drug dextromethorphan.

And finally, from London – According to another report published in the Journal of the American Medical Association, diabetic nephropathy patients who undergo B vitamin therapy may be at increased risk of kidney function decline. Researchers randomized over 200 diabetic patients to either high dose B vitamin therapy or placebo. Results showed that the B vitamin group had poorer kidney function and a greater amount of cardiovascular outcomes, including heart attack and stroke.

HEART DISEASE VIDEO: Unhealthy Habits Raise Risk of Death, Heart Benefit from Antidepressants, Chocolate Linked With Depression

Mon, 26 Apr 2010 17:00:00 EDT

(April 26, 2010 - Insidermedicine)

From Norway - According to a report published in the Archives of Internal Medicine, lack of exercise, poor diet, alcohol consumption and smoking significantly increase ones risk of death when combined. For 20 years, researchers followed nearly 5,000 adults. They found that participants who had all four poor health behaviors had 3x increased risk of death from heart disease or cancer.

From Illinois - SSRI's may provide cardiovascular benefits, according to a report presented at the annual Experimental Biology meeting. Researchers studied 50 adults, half of whom were on the antidepressants. Results of blood tests showed that the platelets of those on antidepressants clumped together slower, thereby improving their cardiovascular health.

And finally, from California - According to another report published in the Archives of Internal Medicine, too much chocolate may be associated with depression. Researchers studied nearly 1000 healthy adults, finding that those who screened highest on depression scores also reported consuming the most amount of chocolate in a month.

ATRIAL FIBRILLATION VIDEO: Diabetics at Risk For Atrial Fibrillation, Stroke Risk Possible With Standard Bypass Procedure, Fish Oil Health Claims May Be False

Fri, 23 Apr 2010 17:00:00 EDT

(April 23, 2010 - Insidermedicine)

From Seattle - According to a report published in the Journal of General Internal Medicine, diabetics are at increased risk of atrial fibrillation. Researchers compared over 1400 atrial fibrillation patients with 2200 controls, finding that people with diabetes had a 40% increased risk of suffering the heart arrhythmia.

From Baltimore - A new report published in the journal Anesthesia & Analgesia outlines how a standard practice during cardiac bypass surgery may increase risk of stroke. Researchers studied over 120 patients who underwent cardiac bypass surgery. They found that the standard practice of cooling and then rewarming a patient during the procedure may actually impair the blood flow to the brain and raises the patients risk of suffering a stroke.

And finally, from London - According to a report published in the American Journal of Clinical Nutrition, fish oil supplements may not be as beneficial as they are claimed to be. Researchers studied over 800 elderly patients, randomizing some to receive omega 3 fatty acid supplements or placebo. Results showed that the fish oil supplements had no noticeable effect on cognitive decline.

COLON CANCER VIDEO: Possible Urine Test for Colon Cancer, Green Tea Fights Eye Diseases, Pollution Connected to Asthma ER Visits for Children

Thu, 22 Apr 2010 19:00:00 EDT

(April 22, 2010 - Insidermedicine)

From North Carolina - According to a report published in the Journal of Proteome Research, advances have been made toward a urine test for colon cancer. Researchers studied urine samples of over 100 people, half with colon cancer and the other half without. They found over 15 substances that appear irregularly in the colon cancer samples, including increased levels of tryptophan.

From Hong Kong - A new report published in the Journal of Agricultural and Food Chemistry outlines how green tea can help fight against eye diseases . Researchers studied the effects of green tea of lab rats, finding that antioxidants indeed passed from the gastrointestinal tract into the retina and aqueous humor, an aspect which may help the eye fight diseases such as glaucoma .

And finally, from Atlanta - Traffic pollution raises the incidence of asthma exacerbations in children, according to a report published in the American Journal of Respiratory and Critical Care Medicine. Researchers studied asthma related pediatric emergency room visits over an 11 year period. They found an increased incidence of asthma exacerbations occurred in the summer, when levels of ozone and traffic pollutants were at their highest.

HEART DISEASE VIDEO: Framingham Score Unreliable in Detection of Atherosclerosis, EGFR Levels Linked With Breast Cancer, Pollution Exposure and Child's Cognitive Ability

Wed, 21 Apr 2010 17:00:00 EDT

(April 21, 2010 - Insidermedicine)

From Connecticut - According to a report published in the American Journal of Roentgenology, low score on a Framingham risk assessment does not rule out heart disease. Researchers studied over 2100 adults with suspected heart disease, finding that the Framingham risk assessment was 74% sensitive at finding atherosclerosis in men and only 36% sensitive in women.

From Washington - Increased levels of epidermal growth factor receptor (EGFR) may be a predictor of breast cancer, according to a report presented at the annual meeting for the American Association for Cancer Research. Researchers studied blood samples of over 400 women 17 months prior to diagnosis of estrogen receptor positive breast cancer, comparing these samples to healthy controls They found that those with the highest EGFR levels had almost 3x increased risk of developing breast cancer.

And finally, from Poland - According to a report published in the journal Environmental Health Perspectives, a mother's exposure to certain air pollutants may affect her child's cognitive ability. Researchers studied over 200 children, finding that those whose mothers had the highest exposure to polycyclic aromatic hydrocarbons during pregnancy had significantly lower scores on standard reasoning and intelligence tests at age 5.

H1N1 VIDEO: Pregnant Women At High Death Risk from H1N1, Early Cochlear Implants Beneficial, No Adverse Effects of Taking Multiple Epilepsy Medications

Tue, 20 Apr 2010 17:00:00 EDT

(April 20, 2010 - Insidermedicine)

From Atlanta - According to a report published in the Journal of the American Medical Association, pregnant women are at increased risk of dying from the H1N1 influenza. Researchers studied nearly 800 cases H1N1 infected pregnant women, finding that 23% had to be admitted to an intensive care unit, and that 5% of these women died.

From Baltimore - Deaf children benefit greatly from receiving an early cochlear implant, according to another report published in the Journal of the American Medical Association. Researchers compared nearly 200 deaf children to 97 healthy controls. Results showed that children who received a cochlear implant before 18 months old were able to hear twice as fast as they would have without the device, while their ability to communicate in return grew almost 1.5x faster.

And finally, from Italy - Taking multiple medications for epilepsy is not associated with adverse effects, according to a report published in the journal Epilepsia. Researchers studied over 800 epileptic patients, finding no noticeable difference in the amount of adverse effects experienced by patients on monotherapy and those on polytherapy.

CANCER VIDEO: Enzyme Predictive of Head and Neck Cancer Survival, Health Benefit of Mediterranean Diet, Gene Variant Protects Against Cognitive Decline

Mon, 19 Apr 2010 19:00:00 EDT

(April 19, 2010 - Insidermedicine)

From Washington - Scientists have identified an enzyme that may predict survival from head and neck cancer, according to a report presented at the annual meeting of the American Association for Cancer Research. Researchers analyzed tissue samples from over 100 squamous carcinoma patients, finding that those with low levels of the enzyme ERCC1 had increased chances of surviving the cancer following adjuvant therapy.

From Spain - A new report published in the journal BMC Genomics outlines the genetic component to the health benefits of the mediterranean diet. Researchers studied 20 patients with metabolic syndrome who followed a mediterranean diet for six weeks. Results showed that intake of phenols--nutrients that are found in virgin olive oil--repressed pro inflammatory genes.

And finally, from Minnesota - According to a report published in the journal Neurology, researchers have identified a genetic variant that may protect memory and thinking skills in the elderly. Studying nearly 3000 elderly patients, researchers found that presence of the Val gene variant had a protective effect on thinking skills and was also associated with a slower cognitive decline.

ASTHMA VIDEO: Vitamin D And Childhood Asthma, Stem Cells From The Gut, Diet Influences Stroke Risk

Fri, 16 Apr 2010 18:00:00 EDT

(April 16, 2010 - Insidermedicine)

From Denver - According to research published in the Journal of Allergy & Clinical Immunology, asthmatic children with low levels of vitamin D, have worse lung function and have higher levels of allergy related proteins in their blood. These children also use more medication to treat their condition.

From Beijing - Researchers have found a new, safe and efficient way to create stem cells. In research published in the journal Cellular Reprogramming; scientists were able to reprogram cells from the human gut into stem cells. These cells have great potential for repairing, or replacing damaged tissues and organs.

And finally, from Japan - In research published in the journal Stroke, women who reported eating foods rich in the B vitamins folate and B-6, had a significantly reduced risk of death from heart disease and stroke. In men, this same dietary pattern reduced their risk of death from heart failure.

ALZHEIMER'S DISEASE VIDEO: Gene Increasing Risk of Alzheimer's Disease, New Treatment for Prostate Cancer, New Drug Reducing Cases of Non-Hodgkin's Lymphoma

Thu, 15 Apr 2010 17:00:00 EDT

(April 15, 2010 - Insidermedicine)

From Toronto - Researchers have identified a gene that appears to increase a person's risk of developing late-onset Alzheimer's disease. According to findings presented at Annual Meeting of the American Academy of Neurology, individuals with a particular variation in the gene MTHFD1L may be almost twice as likely to develop Alzheimer's disease as those without the variation.

From New York - A new treatment for men with an aggressive form of prostate cancer has shown promising anti-tumor activity, according to a study published online in The Lancet. At least half of the patients receiving doses of a new androgen receptor antagonist, saw a 50% decrease in their PSA levels. The drug was associated with tumor regression and improving disease in soft tissue and in bone.

From New York - Researchers from Weill Cornell Medical College have designed a new class of drug that could reduce cases of non-Hodgkin's Lymphoma. Findings published in the journal Cancer Cell highlight an experimental compound that targets the master regulator protein responsible for causing non-Hodgkin's Lymphoma, while having little
adverse effects on normal, healthy cells.

CHILDHOOD OBESITY VIDEO: High BMI Children, Genetics Of Cancer Cells' Life Cycle, Angioplasty Vs Bypass Surgery

Wed, 14 Apr 2010 19:00:00 EDT

(April 14, 2010 - Insidermedicine)

From Georgia - Research presented at the Society of Behavioral Medicine's annual meeting, children with a higher body mass index, more body fat and less endurance have stiffer central arteries than their thinner, leaner counterparts. Stiff arteries are usually seen in adults with atherosclerosis, where blood vessels become clogged with plaque.

From New York - According to new research appearing online in the journal Cancer Cell, the retinoblastoma gene plays a key role in the life cycle of cells. This gene appears to play a role in regulating a cell's ability to divide. Mutations in the retinoblastoma gene are found in many human cancers. The researchers found that when they disabled this gene, cells would continue to divide.

And finally from, Los Angeles - Angioplasty with drug-eluting stents is just as effective as bypass surgery for some types of cardiovascular disease, but carry different risks. The research, appearing in the American Journal of Cardiology, found that the risk of death or heart attack one year after either procedure was not significantly different. They also found that while the risk of stroke was lower with stenting, the risk of a re-clog was higher.

BREAST CANCER VIDEO: Benign Breast Disease, Depression, Chronic Stress

Tue, 13 Apr 2010 19:15:00 EDT

(April 13, 2010 - Insidermedicine)

From St. Louis - Drinking alcohol at a young age increases a woman's risk of benign breast disease, according to research published online in the Journal of Pediatrics. Following over 9,000 young females, ages 9 to 15, for over 11 years, researchers found that young women who drank 6-7 times per week were 5.5 times more likely to have benign breast disease than those who had less than one drink. Benign breast lesions are sometimes linked to later development of invasive breast cancer.

From Michigan - Symptoms for depression are likely to increase among medical interns, according an online report appearing in the June 2010 print issue of Archives of General Psychiatry. The number of study participants who met criteria for depression increased from 3.9% before internship to an average of 25.7% during internship. Stress associated with receiving a medical education includes increased work hours and perceived medical errors.

And finally, from Texas - Chronic stress may accelerate the growth of tumors in patients with ovarian cancer, according to a report in the Journal of Clinical Investigation. In mouse models, stress hormones, specifically norepinephrine and epinephrine protected tumor cells from destruction and promoted their growth. Targeting stress hormones and their signaling pathways may therefore be beneficial to cancer patients.

AMD VIDEO: Macular Degeneration Genes, Anti-smoking Laws Reduce Hospital Admissions, Childhood Exotropia

Mon, 12 Apr 2010 19:00:00 EDT

(April 12, 2010 - Insidermedicine)

From Maryland - Analyzing the genomes of over 18,000 people, researchers have identified 3 new genes that are linked to an increased risk of developing age-related macular degeneration, or AMD. In research published online in the Proceedings of The National Academy of Sciences, researchers found that two of these genes are known to be involved in the HDL cholesterol pathway, potentially opening up new areas for AMD treatments.

From Toronto - Anti-smoking laws appear to have decreased hospital admissions for cardiovascular and respiratory illnesses, according to a report published in the Canadian Medical Association Journal. Researchers examined hospital admission rates for conditions such as heart attacks, stroke, chronic obstructive pulmonary disease and asthma. In municipalities that instituted a restaurant smoking ban there was a 39% decrease in hospital admissions due to cardiovascular conditions, and a 33% decrease in respiratory related admissions.

And finally, from Philadelphia - Children with exotropia, a condition where eyes turn outward when focusing on objects, are at an increased risk of becoming nearsighted later in life. According to an article published in the American Journal of Ophthalmology, slightly more than 90% of children with intermittent exotropia became nearsighted by the time they reached their 20s and needed corrective lenses.

SLEEP APNEA VIDEO: Increases Stroke Risk, Childhood Obesity Rising

Fri, 9 Apr 2010 17:00:00 EDT

(April 9, 2010 - Insidermedicine)

From Michigan - Children are becoming heavier earlier in their lives and carrying that weight for longer, according to a report published in the International Journal of Obesity. 20 percent of people born between 1966-1985 were obese by ages 20-29. Among their parents, that same level of obesity was not reached until ages 30-39. Obesity can lead to type 2 diabetes, cardiovascular disease, disability and premature death.

From Maryland - Obstructive sleep apnea is associated with an increased risk of stroke in middle-aged and older adults, especially among men, according to a report published online ahead of print in the American Journal of Respiratory and Critical Care Medicine. Men with moderate to severe sleep apnea were nearly three times more likely to have a stroke than those with no or mild sleep apnea. In women, the link was only found in patients with severe sleep apnea.

KIDNEY CANCER VIDEO: Urine Test For Kidney Cancer, Measles in BC, Private Practice Owners

Thu, 8 Apr 2010 20:30:00 EDT

(April 8, 2010 - Insidermedicine)

From British Columbia - The B.C. Centre for Disease Control reports 26 confirmed cases of measles in the province, with most of the cases appearing in Metro Vancouver. In fourteen of the cases, the patients were unvaccinated, while the others had an uncertain vaccination history. In North America most children are vaccinated before the age of two. The center has identified the two strains responsible for the outbreak, and suspect they were both imported from overseas.

From St Louis - A new way to screen for kidney cancer is on the horizon. Currently, there is no diagnostic test for kidney cancer, and most are discovered during a CT or ultrasound test for another condition. In a report published online in Mayo Clinic Proceedings, researchers found elevated levels of two proteins in the urine of those with kidney cancer. The increased presence of these proteins appears to identify 90% of all kidney cancers.

And finally, from Michigan - Doctors with a financial stake in an outpatient surgery center perform more procedures, according to a new report published in the journal Health Affairs. Gathering data in Florida, researchers examined the surgical volume of physicians before and after they became owners of a surgical center, as well as the volume from physicians who remained non-owners. On average, those physicians who did own a surgical center performed twice as many procedures.

FLU SHOT VIDEO: More Effective Flu Shot, Walking Reduces Stroke Risk, Eggs Reduce Appetite

Wed, 7 Apr 2010 20:00:00 EDT

(April 7, 2010 - Insidermedicine)

From St. Louis - According to a report published in the journal Vaccine, adding a second strain of the Influenza B virus to the seasonal flu shot would increase its effectiveness. Typically the flu shot contains two variations of the influenza A virus, and one of influenza B. In animal trials, researchers found that immunizing against a single strain of influenza B did not appear to protect against the other.

From Dallas - Researchers have found that walking can reduce a woman's stroke risk, according to a report in the journal Stroke. Researchers followed nearly 40,000 women for almost 12 years, with the women completing a questionnaire every few years estimating their physical activity. Those women who reported walking at a brisk pace, 3 miles per hour or faster, had a 37% lower risk of stroke. And similarly, those women who reported walking for at least two hours a week had a 30% lower risk of stroke.

And finally, from Illinois - According to a report published in the journal Nutritional Research, eating eggs for breakfast appears to reduce a person's appetite for the rest of the day. Researchers compared two groups of men, one eating a protein-rich egg breakfast, the other eating a carbohydrate based breakfast. Those who had the egg breakfast consumed 400 fewer calories during the day. In blood tests, a hormone that reflects hunger was found to be much higher in the men who consumed the carbohydrate based meal.

ANXIETY VIDEO: Exercise As Treatment For Mood Disorders, Behavioral Test For MCI, Exercise During Pregnancy

Tue, 6 Apr 2010 19:00:00 EDT

(April 6, 2010 - Insidermedicine)

From Dallas - According to research presented at the annual conference of the Anxiety Disorder Association of America, exercise should be prescribed more often for people with depression and anxiety disorders. In examining numerous studies, researchers found substantial support for using exercise to help treat mood disorders. The researchers recommend that patients slowly increase their physical activity to 150 minutes a week of moderate activity, or 75 minutes of vigorous exercise.

From Pennsylvania - According to a report published in the Journal of Mathematical Psychology using a simple question and answer behavioral test, researchers were able to detect changes in the progression of mild cognitive impairment, or MCI. MCI is typically diagnosed by measuring a decrease in volume of the hippocampus using a MRI scan. This new method would be less expensive, and be useful when MRI imaging is unavailable.

And Finally, from Maryland - Moderate exercise during pregnancy can reduce the birth weight of infants according to a new report published in the Journal of Clinical Endocrinology & Metabolism. High birth weight carries with it a number of complications for the infant. Yet in previous studies in the non-pregnant population, exercise reduced insulin resistance. The researchers were concerned that if this same reduction occurred in pregnant women, it might have a major affect on fetal nutrition. However they found that exercise had no affect on maternal insulin sensitivity.

WEIGHT LOSS VIDEO: Self Guided Program Successfully Curbs Binge Eating, Early CT and MRI Scans Cut Costs and Shorten Stays, Rheumatoid Arthritis and Knee Replacement Surgery

Thu, 1 Apr 2010 20:00:00 EDT

(April 1, 2010 - Insidermedicine)

From Oregon - According to a report published in the Journal of Consulting and Clinical Psychology, a self guided, short term program has shown success in curbing binge eating. Researchers studied over 100 patients with a history of binge eating, having the patients read an instructional book and then attend a series of therapy sessions over 12 weeks. Results showed that upon study completion, 63% of participants had stopped binge eating.

From Boston - According to a report published in the Journal of the American College of Radiology, early CT and MRI scans can shorten the amount of time a patient stays in hospital. Researchers studied over 10, 000 hospital admissions, finding that patients had a significantly shorter stay in the hospital when imaged either the day before or day of admission, when compared to those imaged on day 1 or day 2 following admission.

And finally, from Norway - Rheumatoid arthritis patients who undergo knee replacement are at increased risk of infection, according to a report published in Arthritis Care and Research. Studying over 6,800 knee replacement surgeries, researchers found that RA patients who underwent the procedure were 1.6x more likely than those with osteoarthritis to get an infection that required subsequent revision.

HIV VIDEO: Stem Cells Might Be Used to Treat HIV, Communication Breakdown in Brain Linked with Schizophrenia, Wealth Disparity Between Female and Male Researchers

Wed, 31 Mar 2010 19:00:00 EDT

(March 31, 2010 - Insidemedicine)

From Scotland - According to a report presented at the meeting for the Society for General Microbiology, stem cell therapy could in the future be used to treat HIV. Researchers are studying a new approach that would deliver antiviral DNA to the immune system, consequently arming it with a defense against viral infection. This approach would involve extracting blood stem cells from the patient's bone marrow and infusing them with this antiviral DNA.

From New York - Scientist have identified a disrupted brain connection that may be associated with schizophrenia, according to a report published in the journal Nature. Researchers studied mice that were altered to have a genetic mutation known to occur in schizophrenics. They found that these mice had a communication breakdown in their brains between the hippocampus and prefrontal cortex, an area known to affect cognitive behavior.

And finally, from Boston - Female researchers are paid significantly less than males, according to a report published in the journal Academic Medicine. Surveying over 2000 researchers, results showed that females earned an average of over $13,000 yearly less than males--an aspect that the study authors were at a loss to explain.

HEART DISEASE VIDEO: Chocolate Reduces Heart Disease Risk, Radiation Following Mastectomy Underused, Young Adults Over Rely on Emergency Department

Tue, 30 Mar 2010 17:00:00 EDT

(March 30, 2010 - Insidermedicine)

From Germany - Chocolate may lower blood pressure and reduce risk of heart disease, according to a report published in the European Heart Journal. Researchers studied nearly 20000 adults for 10 years, finding that those who ate an average of 7.5 grams of chocolate each day had lower blood pressure as well as a 39% reduced risk of suffering a heart attack or stroke.

From Michigan - According to a report published in the Journal of Clinical Oncology, radiation therapy following mastectomy may be underused. Researchers studied over 2000 breast cancer patients, finding that 95% of those who underwent a lumpectomy were treated with radiation therapy afterwards, while only 78% who underwent mastectomy received radiation.

And finally, from Rochester - According to a report published in the Journal of General Internal Medicine, young adults rely on emergency departments far more than any other age group. Researchers reviewed data on over 17000 visits to the emergency room and over 14000 outpatient visits, finding that 22% of all young adult healthcare visits were made to the emergency room, while only 13% of children visits and 8% of visits for people over 30 were made to the ER.

DIABETES VIDEO: Possible New Approach to Treat Type 2 Diabetes, Deep Vein Thrombosis in Pregnant Women, Breastfeeding and Breast Cancer

Mon, 29 Mar 2010 17:00:00 EDT

(March 29, 2010 - Insidermedicine)

From Boston – Researchers may have identified a new approach type 2 diabetes, according to a report published in the journal Nature Medicine. Researchers found a certain cellular pathway that fails when one becomes obese, subsequently stifling the body’s response to insulin. When this pathway was activated in obese mice, however, researchers found that the rodent’s blood glucose levels normalized.

From Toronto – According to a report published in the Canadian Medical Association Journal, pregnant women are more likely to suffer deep vein thrombosis on their left side. Out of over 1000 studies reviewed, researchers found only a limited amount that examined DVT in pregnant women. From these studies however, researchers were able to discern that DVT is in fact common in pregnancy, and typically found in the left leg.

And finally, from Spain – According to a report presented at the European Breast Cancer conference, women who breastfeed longer may be at increased risk of developing aggressive breast tumors. Researchers studied over 14,000 women for 10 years, finding that those who breastfed their child longer than 6 months had 2x increased risk of developing grade III breast cancers.

BREAST CANCER VIDEO: Beta Blockers Reduce Breast Cancer Metastasis Risk, Two Genes Implicated in Autism, HER2 Levels During Breast Cancer Treatment

Fri, 26 Mar 2010 17:00:00 EDT

(March 26, 2010 - Insidermedicine)

From Spain - According to a report presented at the European Breast Cancer Conference, treating breast cancer patients with beta-blockers may reduce their risk of metastasis. Researchers studied over 450 breast cancer patients, finding that those who were already taking beta-blockers to treat hypertension also had a dramatically reduced risk of recurrence and metastasis, as well as a 71% lower risk of dying from the disease.

From Oxford - Scientists have identified two genes related to autism, according to a report published in the journal Molecular Autism. Studying over 650 families, researchers found that two genes associated with brain development known as LRRN3 and LRRTM3 were connected to susceptibility of autism spectrum disorders.

And finally, back to Spain - According to another report presented at the European Breast Cancer Conference, HER2 levels during breast cancer therapy may be a predictor of the patients response to treatment. Researchers studied nearly 200 breast cancer patients, finding that those who had higher levels of HER2 at the onset of treatment and saw their levels decline by at least 20% were more likely to respond well to their chemotherapy.

KIDNEY DISEASE VIDEO: Many Americans Unknowingly Suffer From Kidney Disease, How Tumors Trick Immune System, Most Kidney Transplantation Candidates Take On Infection Risk

Thu, 25 Mar 2010 19:00:00 EDT

(March 25, 2010 - Insidermedicine)

From San Francisco - According to a report published in the Clinical Journal of the American Society Nephrology, many Americans suffer from kidney disease and do not know it. Researchers studied nearly 8200 adults, finding that 42% of those with undiagnosed diabetes also had chronic kidney disease, while CKD was seen in 18% of those with prediabetes.

From Switzerland - Scientists provide new insight into how tumors hide from the immune system in a report published in the journal Science. Researchers found that a particular protein that is normally secreted by the lymph nodes to signal the immune system to start working is also secreted by tumors. In this way, the tumor signals to the immune system that it is a friend not foe and consequently goes undetected by the immune system.

And finally, from Pennsylvania - According to another report published in the Clinical Journal of the American Society Nephrology, most patients awaiting a kidney donation are willing to accept one from a donor that puts them at increased risk of infection. Researchers surveyed nearly 200 potential kidney transplant patients. 59% of these patients said they would--under some conditions--accept a kidney from a donor even if they were at increased risk of viral infection.

BREAST CANCER VIDEO: Breast Cancer Recurrence and Metastasis Risk, Rise in Caesarian Sections In US, HIV Patients at Increased Risk for Community Acquired MRSA

Wed, 24 Mar 2010 17:00:00 EDT

(March 24, 2010 - Insidermedicine)

From Spain - According to a report presented at the European Breast Cancer Conference, recurrence of breast cancer is the strongest indicator of eventual metastasis and death. Researchers studied nearly 8,000 breast cancer patients for almost 11 years. They found that recurrence of breast cancer in the original area of the tumor was the strongest prognostic factor of eventual metastasis of the disease, even for women who were disease free for ten years.

From Atlanta - According to a report released by the CDC, the amount of Caesarean sections performed in the US are on the rise. Researchers found that in 2007, c-sections rose to become 32% of all births--a number that represents a 71% increase from 1996.

And finally, from Chicago - HIV patients are at significantly increased risk of community acquired MRSA, according to a report published in the journal Clinical Infectious Diseases. Reviewing regional data over a seven year period, researchers found that HIV patients were 6x more likely than non-HIV patients to contract CA-MRSA.

BLOOD PRESSURE VIDEO: High Systolic Blood Pressure in Chest Pain Patients, Clinical Trials and Exaggerated Outcomes, Preventable Factors Reduce Life Expectancy

Tue, 23 Mar 2010 17:00:00 EDT

(March 23, 2010 - Insidermedicine)

From Sweden - A high systolic blood pressure reading in chest pain patients admitted to an ICU may be associated with a favorable outcome, according to a report published in the Journal of the American Medical Association. Researchers reviewed data on nearly 120,000 patients admitted to an ICU with chest pain, finding that patients with a high supine systolic blood pressure reading had the most favorable 1 year prognosis.

From Minnesota - According to another report published in the Journal of the American Medical Association, clinical trials tend to exaggerate their positive effects when stopped early. Researchers studied nearly 100 clinical trials that were stopped early, finding that these truncated trials had either misleading or exaggerated treatment effects.

And finally, from Boston - According to a report published in the journal Public Library of Science Medicine, there are 4 preventable factors that combine to reduce life expectancy in the US. Researchers studied national surveys, finding that smoking, high blood pressure, high blood sugar and obesity combine to reduce life expectancy by 4.1 years in women and 4.9 years in men.

HEALTH CARE VIDEO: US Passes New Health Care Bill, Racial Disparities in Stroke Treatment, X Rays Inaccurate with Hip and Pelvic Fractures

Mon, 22 Mar 2010 17:00:00 EDT

(March 22, 2010 - Insidermedicine)

From Washington - The United States House of Representatives has approved a landmark legislation aimed at overhauling the American health care system. The legislation intends to provide health care for the 32 million Americans currently uninsured, aiming to create new regulations to preclude insurance companies from denying coverage and making insurance premiums unaffordable.

From Boston - According to a report published in Circulation: Journal of the American Heart Association, African Americans are less likely to receive evidence-based care following a stroke than Caucasians or Hispanics. For five years, researchers studied nearly 400,000 black, white and hispanic stroke patients. Results showed that black stroke patients were 10% less likely than white patients to receive 'defect free care'--or, to receive all of the treatments that they are eligible for.

And finally, from North Carolina - According to a report published in the American Journal of Roentgenology, x rays are frequently inaccurate in diagnosing pelvic and hip fractures. Researchers studied nearly 100 patients who underwent both x ray and MRI for suspected hip and pelvic fractures. Of 13 patients with a normal x ray, MRI found 23 fractures; while 11 patients who had an x ray that suggested a fracture had an MRI that showed none at all.

MRSA VIDEO: Infection Control Measures Against MRSA, Extreme Obesity in US Kids, Pregnancy and H1N1 Flu

Fri, 19 Mar 2010 17:00:00 EDT

(March 19, 2010 - Insidermedicine)

From Atlanta - According to a report presented at the International Conference on Healthcare-Associated Infections, simple infection control measures appear to work against MRSA. For seven years, researchers studied the effect that measures such as hand hygiene, chlorhexidine bathing, and device-related efforts had against hospital acquired infections. They found a 91% reduction in MRSA bloodstream infections, 62% reduction in MRSA catheter infections, and 92% reduction in MRSA ventilator related pneumonia.

From California - Extreme obesity is becoming more and more common among children in the US, according to a report published in the Journal of Pediatrics. Researchers studied over 700,000 children, finding that 37% of the children were overweight and 19% were obese, while 5% of girls and 7% of boys in the study were extremely obese.

And finally, from Australia - According to a report published in the British Medical Journal, pregnant women who get the H1N1 flu are at increased risk of critical illness. Researchers studied over 200 women admitted to ICU with confirmed H1N1, finding that pregnant women were 13x more likely to be hospitalized with a critical illness.

PREGNANCY VIDEO: Stress During Pregnancy, Scientists Reduce Smoking Related Lung Inflammation in Mice, Selenium Reduces Diabetes Risk in Men

Thu, 18 Mar 2010 17:00:00 EDT

(March 18, 2010 - Insidermedicine)

From Boston - Stress during pregnancy may increase risk of asthma in the child, according to a report published in the American Journal of Respiratory and Critical Care Medicine. Researchers studied 557 families, analyzing the child's umbilical cord for cytokines--a molecule that allows cells of the immune system to communicate with one another. They found varying levels of cytokines in mothers who lived or worked in a high stress environment, an aspect researchers believe increases the child's risk of allergy and asthma later in life.

From Australia - According to another report published American Journal of Respiratory and Critical Care Medicine, scientists have developed a technique that may be able to reduce tobacco smoke damage to the lungs. Researchers blocked the protein GM-CSF in one group of mice, while another served as controls. Exposing both groups to cigarette smoke, researchers found that the mice without the protein suffered significantly less lung inflammation than controls.

And finally, from France - The element Selenium may have a protective effect against diabetes, according to a report published in the journal Nutrition and Metabolism. Researchers studied over 1000 adults for nine years, finding that men with the highest selenium concentrations in their blood had a much lower incidence of dysglycemia (blood sugar metabolism disorders such as diabetes.)

HEART FAILURE VIDEO: Weighing Less Does Not Reduce Risk of Sudden Cardiac Death, New TB Booster Shot, Risks of Obesity and Smoke Exposure During Pregnancy

Wed, 17 Mar 2010 17:00:00 EDT

(March 17, 2010 - Insidermedicine)

From Atlanta - Being skinny does not reduce risk of sudden cardiac death, according to a report presented at the American College of Cardiology meeting. Researchers studied over 1200 patients with a history of at least one heart attack, finding that non-obese heart failure patients were at 76% increased risk of sudden cardiac death when compared to obese heart failure patients.

From South Africa - According to a report published in the American Journal of Respiratory and Critical Care Medicine, a new tuberculosis booster shot may improve resistance in adults. Researchers developed the Aeras-402 vaccine by weakening TB virus to the point that it could no longer replicate, inserting antigens that would then stimulate the immune system. The vaccine was proven safe in humans and shown to stimulate the immune system to further protect against TB.

And finally, From Egypt - According to a report published International Journal of Food Safety, Nutrition and Public Health, obese pregnant women or those who have been occasionally exposed to smoke during pregnancy may put their child at increased risk of future health problems. Researchers studied the umbilical cords of 65 babies, finding that mothers who were obese during pregnancy, or who smoked passively during pregnancy, reduced the amount of oxygen that reached their unborn child.

LUNG CANCER VIDEO: Precise Radiation Therapy Improves Lung Cancer Outcomes, Antidepressants Help Physically Ill, Cardiac Rehab for Patients Post Stent Placement

Tue, 16 Mar 2010 19:00:00 EDT

(March 16, 2010 - Insidermedicine)

From Dallas - According to a report published in the Journal of the American Medical Association, lung cancer survival rates may improve with precision radiation therapy. Researchers studied over 50 lung cancer patients who were unable to undergo surgery to remove their tumors. They found that lung cancer did not recur in nearly 98% of participants who underwent precision radiation therapy, and that 56% still lived three years following their diagnosis.

From the UK - Antidepressants appear to help patients suffering from physical illnesses, according to a report published in the Cochrane Library. Researchers reviewed 51 studies covering over 3600 patients with physical illnesses such as stroke, HIV/AIDS and cancer. They found that antidepressants proved more effective than placebos at treating depression in these patients.

And finally, from Atlanta - According to a report presented at the American College of Cardiology meeting, heart patients who received a stent may find their survival improve with cardiac rehabilitation. Researchers studied over 2300 patients who underwent stent placement, finding up to 47% decrease in mortality among those who participated in cardiac rehabilitation.

HEART DISEASE VIDEO: Vitamin D and Heart Disease Risk, Nasal CPAP in Newborns Linked to Ventilation Complications, Plaques Seen on CT Increase Risk of Coronary Artery Disease

Mon, 15 Mar 2010 17:00:00 EDT

(March 15, 2010 - Insidermedicine)

From Atlanta - According to a report presented at the American College of Cardiology meeting, vitamin D supplementation may reduce risk of heart disease. Researchers studied nearly 10,000 patients with low vitamin D levels, finding that 47% of those who raised their vitamin D levels after one year had a lower risk of heart disease.

From Ohio - Newborns who receive oxygen supplementation with nasal CPAP may be at increased risk of developing nasal ventilation complications, according to a report published in the Archives of Otolaryngology–Head & Neck Surgery. Researchers studied 100 newborns who underwent either nasal CPAP or oxygen supplementation with cannula. They found that 13% of those who underwent nasal CPAP developed nasal complications, while those who received the nasal cannula developed no such problems.

And finally, back to Atlanta - According to another report presented at the American College of Cardiology meeting, plaques seen on a CT scan predict heart disease. Researchers studied nearly 400 patients with an abdominal CT scan, finding that those who had extremely high levels of abdominal aortic calcium (or, plaque) had a 60% increased risk of coronary artery disease, as well an increased risk of mortality.

PREGNANCY VIDEO: Flu During Pregnancy Linked to Schizophrenia, Obesity Plus Alcohol Connected to Liver Disease, Psoriasis and Pregnancy Complications

Fri, 12 Mar 2010 17:00:00 EDT

(March 12, 2010 - Insidermedicine)

From North Carolina - According to a report published in the journal Biological Psychiatry, pregnant women who get the flu may increase their child's risk of schizophrenia. Researchers infected rhesus monkeys in their third trimester with influenza. MRI scans of the babies after 1 year revealed brain changes similar those seen in humans with schizophrenia.

From Oxford - According to a report published in the British Medical Journal, obesity and alcohol consumption combine to drastically increase ones risk of liver disease. Researchers studied data on over 1.2 million women, finding that women with a BMI between 22.5 and 25 who consumed more than 150 grams of alcohol a week were at 170% increased risk of liver disease, while women with a BMI of 30 or more saw their risk raised by 400%.

And finally, from Miami - Pregnant women with psoriasis are at increased risk of complications, according to a report presented at annual meeting of the American Academy of Dermatology. Researchers compared a group of pregnant psoriasis patients to over 130,000 pregnant women without psoriasis. Results showed that the psoriasis patients were up to three to four times more likely to experience complications such as preterm birth, preeclampsia, spontaneous abortion and ectopic pregnancy.

ANGIOGRAPHY VIDEO: Possible Overuse of Common Heart Test (Interview with Dr. Manesh Patel, MD, Duke University)

Fri, 12 Mar 2010 17:00:00 EDT

(March 12, 2010 - Insidermedicine)

Less than half of individuals without known heart disease who are undergo invasive testing of the coronary blood vessels are found to have significant obstructions in these vessels, , according to research published in the New England Journal of Medicine.

Here is some information about coronary angiography:

•    It is a procedure in which dye is injected into the body and then X-rays are used to visualize blood flow through the vessels that feed the heart.

•    It is usually done along with catheterization, in which a balloon-tipped catheter is threaded into the coronary arteries to achieve a better view of the vessels and remove any blockages that are found

•    The procedure carries with it a very small risk of a serious adverse event, including a heart attack or stroke

Researchers from Duke University Medical Center in Durham used a national cardiovascular registry to identify nearly 400,000 individuals without known heart disease who underwent coronary catheterization to look for obstructions in the blood vessels that feed the heart. Left untreated, such obstructions can lead to a heart attack or stroke. The investigators also looked at whether certain characteristics of the individuals, including their sex, age, the presence of other medical conditions, and the results of less invasive tests, could predict who would eventually be diagnosed with one or more obstructions.

Catheterization revealed the presence of an obstruction in only about 38% of the individuals tested. In addition, a lack of obstructive disease was confirmed in 39% of the individuals. Men, those who were older, those with insulin-dependent diabetes, and those with high cholesterol levels were all more likely to have obstructions in their coronary arteries. Those who had positive findings on noninvasive tests were only 28% more likely to have an obstruction than those who underwent no such testing.

We spoke with Dr. Manesh Patel, one of the investigators of this study, who offered some further insight.

Today’s research highlights the need to do a better job of identifying who is likely to have obstructive coronary artery disease before sending individuals for invasive coronary angiography and catheterization.

STROKE VIDEO: Blood Pressure Variability Linked to Stroke Risk, Diabetes Possibly Associated with Meal Anticipation, Knee Replacement Improves Balance, Relieves Pain

Thu, 11 Mar 2010 19:00:00 EDT

(March 11, 2010 - Insidermedicine)

From Oxford – Inconsistent systolic blood pressure readings may be a predictor of stroke, according to a report published in The Lancet. Researchers followed over 8, 000 patients through seven doctor visits, finding that those who had the most variation in their systolic blood pressure had a 6x increased risk of stroke, while patients with the highest blood pressure had a 15x increased risk of stroke.

From North Carolina – According to a report published in the journal Diabetes Care, anticipating a meal may be a risk factor for diabetes. Researchers compared over 500 diabetic patients to nearly 500 healthy controls, believing that when one anticipates or smells food, the nervous system triggers the body to salivate and thereby increases the production of insulin. They found that alterations to the gene that is responsible for this process may be a risk factor for type 2 diabetes.

And finally, from Israel – According to a report presented at the annual meeting of the American Academy of Orthopaedic Surgeons, elderly patients who undergo knee replacement may have improved balance. Researchers studied 63 patients with knee arthritis, finding that total knee replacement resulted in not only pain relief, but also significantly improved balance and the ability to complete daily activiaties.

CHOLESTEROL VIDEO: Doctors Inadequately Target LDL Cholesterol Levels, Obesity and Colon Cancer Prognosis, Youth Baseball Players and Arm Injuries

Wed, 10 Mar 2010 19:00:00 EDT

(March 10, 2010 - Insidermedicine)

From Germany - According to a report published in the European Heart Journal, many doctors fail to adequately lower their patient's cholesterol. Researchers studied over 25,000 patients and just over 900 doctors, finding that just 49% of female patients and 55% of male patients were given correct targets for lowering their LDL cholesterol levels.

From Minnesota - According to a report published in the journal Clinical Cancer Research, obese people may be at increased risk of dying from colon cancer. Researchers studied over 4300 colon cancer patients, finding that obese males in particular were at 35% increased risk of dying from the disease.

And finally, from Japan - An increasing amount of youth baseball players are incurring injuries to their throwing arms, according to a report presented at the annual meeting of the American Academy of Orthopaedic Surgeons. Researchers studied over 150 youth baseball players, finding that 25% experienced elbow pain, 68% had limited range of motion in their elbow, and that 85% suffered osteochondral lesions.

FLU VIDEO: Vaccinating Children Against Flu Preventive and Protective, Lung Cancer Risk with Gene Variant, Alzheimer's Risk for African Americans and Hispanics

Tue, 9 Mar 2010 17:00:00 EDT

(March 9, 2010 - Insidermedicine)

From Hamilton - According to a report published in the Journal of the American Medical Association, vaccinating children against the flu may prevent transmission in ones community. Researchers studied over 2300 people from different communities who were not vaccinated for the flu, randomizing nearly 1000 children to receive either an influenza vaccine or a control vaccine. They found that communities in which children received the influenza vaccine had a lower incidence of the flu.

From Cincinnati - Light smokers with a specific genetic variation are at increased risk of lung cancer, according to a report published in the journal Cancer Research. Researchers studied people with varying degrees of smoke exposure, finding that even those who smoked a minimal amount of cigarettes over 20 years and who had a certain genetic variant were at a significant increased risk of lung cancer.

And finally, from Washington - According to a report released by the Alzheimer's Association, African Americans and Hispanics are more likely to develop Alzheimer's disease. Researchers estimate that African Americans are nearly 2x as likely as Caucasians to develop dementia, while Hispanics are about 1.5x more likely.

AMD VIDEO: Eye Injections Increasing for Age Related Macular Degeneration, Sunlight Exposure at Work and Kidney Cancer Risk, Alcohol and Weight Loss in Women

Mon, 8 Mar 2010 17:00:00 EDT

(March 8, 2010 - Insidermedicine)

From Kingston - According to a report published in the Archives of Ophthalmology, eye injections are becoming more and more common for the treatment of age related macular degeneration. Researchers from Queen's University found that from 2005 to 2007, the amount of intravitreal injections for AMD in Ontario increased eight fold. However, the amount of ophthalmologist who perform these injections only increased by 5% during this time span.

From Maryland - Occupational sunlight exposure may lower risk of kidney cancer in men, according to a report published online in the journal Cancer. Researchers studied over 2500 people--nearly 1100 of who had kidney cancer--finding that sunlight exposure at work resulted in a 24 to 38% reduced risk of kidney cancer.

And finally, from Boston - According to a report published in the Archives of Internal Medicine, moderate alcohol consumption may slow weight gain in women. Researchers studied over 7,000 women for 13 years, finding that women who drank between 15 to 30 g of alcohol per day had nearly 30% reduced risk of becoming overweight or obese when compared to women who drank none at all

LUNG CANCER VIDEO: Optimism Helps for Lung Cancer Patients, Grass Allergy Tablet Successful, Cataract Risk for Women Undergoing Hormone Replacement Therapy

Fri, 5 Mar 2010 20:00:00 EDT

(March 5, 2010 - Insidermedicine)

From Minnesota - According to a report published in the Journal of Thoracic Oncology, optimistic lung cancer patients may live longer than pessimistic patients. Researchers studied over 500 lung cancer patients, using personality scores from a test taken 18 years before their diagnosis. Results showed that optimistic patients lived an average of six months more than pessimistic patients.

From New Orleans - A new tablet may be able to reduce symptoms of grass allergy, according to a report presented at the annual meeting for the American Academy of Allergy, Asthma & Immunology. Researchers studied 344 children, randomizing some to placebo or to the tablet that contains Timothy grass pollen. Results showed that children taking the tablet (which is placed under the tongue) scored 26% better on symptom scores than placebo.

And finally, from Sweden - According to a report published in the journal Ophthalmology, women on hormone replacement therapy who regularly drink alcohol are at significant increased risk of cataracts. Researchers studied over 30,000 postmenopausal women, finding that those currently undergoing HRT who drank one or more alcoholic drink daily had a 42% increased risk of developing cataracts.

SKIN CANCER VIDEO: Vitamin D Connected to Skin Cancer, Lung Cancer Risk for Women on Hormone Replacement Therapy, Proteins Connected to Colon Cancer Identified

Thu, 4 Mar 2010 19:00:00 EDT

(March 4, 2010 - Insidermedicine)

From Detroit - Elevated vitamin D levels may be linked with skin cancer, according to a report presented at the annual meeting for the Photomedicine Society. Researchers compared skin tissue samples of 10 basal cell carcinoma patients with 10 healthy patients. The skin cancer patients had 10x the amount of Vitamin D enzyme levels and 2x the amount of Vitamin D protein levels.

From Oregon - Women on hormone replacement therapy may be at increased risk of lung cancer, according to a report published in the Journal of Clinical Oncology. Researchers reviewed data on over 36,000 women, finding that taking estrogen plus progestin for over 10 years was associated with a 50% increased risk of lung cancer.

And finally, from China - According to a report published in the Journal of Proteome Research, scientists have identified two proteins that may predict metastases of colon cancer. Researchers compared primary tumor cells to metastasized cells, finding two specific proteins occurring in elevated levels in the latter. This discovery could potentially lead to a blood test able to predict the spread of colon cancer.

BREAST CANCER VIDEO: Breast Cancer Recurrence With Delayed Radiotherapy, Secondhand Smoke Affects Children's Arteries, ICU Visits and Death Risk

Wed, 3 Mar 2010 17:00:00 EDT

(March 3, 2010 - Insidermedicine)

From Boston - According to a report published online in the British Medical Journal, long intervals between breast cancer surgery and radiotherapy may increase risk of the disease recurring. Researchers reviewed records on over 18,000 women who underwent breast conserving surgery followed by radiation therapy. They found that initiation of radiotherapy six or more weeks following surgery was associated with an increase in local recurrence.

From Finland - According to a report published in the journal Circulation: Cardiovascular Quality and Outcomes, children exposed to secondhand smoke are at increased risk of hardened arteries. Researchers studied nearly 500 children for 5 years, finding that those with higher secondhand smoke exposure saw their blood vessel walls thicken significantly.

And finally, from New York - ICU visits increase ones risk of death, according to a report published in the Journal of the American Medical Association. Researchers reviewed data on over 35,000 patients discharged from an intensive care unit, finding that these ICU patients were at 7% increased risk of death over a three year period when compared to patients that were hospitalized for non critical care.

BREAST CANCER VIDEO: Breast Cancer Lowered With Osteoporosis Drug, Coffee Decreases Arrhythmia, Ovarian Cancer Diagnosis Delayed in Older Women

Tue, 2 Mar 2010 21:00:00 EDT

(March 2, 2010 - Insidermedicine)

From Seattle - Several osteoporosis drugs may lower risk of breast cancer, according to a report published in the British Journal of Cancer. Studying nearly 6,000 women, half of whom had breast cancer while the other half did not, results showed that using bisphosphonate drugs for more than two years resulted in a 40% reduced risk of breast cancer.

From California - According to a report presented at the American Heart Association's annual conference on Cardiovascular Disease Epidemiology and Prevention, drinking coffee may reduce ones risk of hospitalization for heart rhythm disturbances. Researchers studied over 130,000 people, finding that those who reported drinking at least four cups of coffee a day were at 18% decreased risk of being hospitalized for arrhythmia.

And finally, from the UK - According to another report published in the British Journal of Cancer, older women who may have ovarian cancer are being referred for investigation later than younger women. Researchers reviewed patient records over a 4 year period, finding that 66% of women over the age of 70 received a further investigation a year before their diagnosis of ovarian cancer, compared with 82% of women under the age of 55.

DIABETES VIDEO: Gestational Diabetes Prevalence to Increase, Wii May Help Stroke Survivors, Smoking Raises Risk of Aneurysm in Certain People

Fri, 26 Feb 2010 17:00:00 EDT

(February 26, 2010 - Insidermedicine)

From Chicago - According to a report published in the journal Diabetes Care, the prevalence of gestational diabetes is going to increase dramatically. Researchers created new measurements of dangerous blood sugar levels based on a study covering over 23,000 women. Because of these new measurements, researchers estimate that as many as three times more pregnant women will be diagnosed with gestational diabetes.

From Toronto - Using Nintendo Wii may help stroke patients repair their motor function, according to a report presented at the American Stroke Association's International Stroke Conference. Researchers randomized 20 stroke survivors to use the Wii or to play recreational games such as cards. They found that the gaming system produced no adverse effects and actually resulted in significant improvement in motor function.

And finally, from San Antonio - According to another report presented at the American Stroke Association's International Stroke Conference, people with certain genetic variations find their risk of aneurysm increase significantly with smoking. Researchers found that people who had one particular genetic variation were up to 48% increased risk of suffering an aneurysm. When these people smoked an equivalent of a pack of cigarettes a day for up to 20 years, however, this risk was raised more than five fold.

HEART ATTACK VIDEO: Heart Attack Risk for Dialysis Patients, Single Men May Face Risk of Stroke, Heart Disease Biggest Killer in US

Thu, 25 Feb 2010 19:00:00 EDT

(February 25, 2010 - Insidermedicine)

From Japan - According to a report published in the Clinical Journal of the American Society of Nephrology, dialysis patients feeling high levels of fatigue may be at increased risk of heart attack. Researchers studied nearly 800 dialysis patients, finding that of 16% of patients with a high fatigue score, risk of heart attack or stroke was more than doubled.

From Israel - According to a report presented at the American Stroke Association's International Stroke Conference, men who are single or unhappily married may be more likely to suffer a fatal stroke. Researchers reviewed data on over 10,000 people who participated in a 1963 survey. They found that single men had 64% increased risk of suffering a fatal stroke, while unhappily married men also had a 64% increased risk.

And finally, from Atlanta - Heart disease is still the leading cause of death in the US, according to an editorial published in The Lancet. Citing a report from the CDC, the editorial states that in 2006 heart disease killed over 630,000 Americans. Certain lifestyle factors make heart disease particularly difficult to stop, as 20% of Americans smoke, 33% are obese, and only 33% are regularly active.

BREAST CANCER VIDEO: Breast Cancer Screening Option for Women at High Risk, New Approach To Reduce Stroke Damage, Cochlear Implant Good for Deaf Child's Quality of Life

Wed, 24 Feb 2010 17:00:00 EDT

(February 24, 2010 - Insidermedicine)

From Boston - According to a report published in the journal Radiology, young women at high risk for breast cancer may benefit from yearly combined screening of mammography and MRI. Researchers estimated the number of quality adjusted life years that high risk women would gain from annual combined screening, finding that these women could gain up to 50 QALYs.

From San Antonio - A new approach to reducing stroke damage has been presented at the International Stroke Conference. Researchers are examining a new field of study--known as ischemic preconditioning--in which blood supply to a particular organ is purposely reduced in an effort to prepare the organ's tolerance of operating with limited blood supply. Researchers believe that using a blood pressure cuff, for example, could condition the brain to operate in such a way that would thereby reduce damage incurred by a stroke.

And finally, from Dallas - According to a report published in Otolaryngology – Head and Neck Surgery, cochlear implants appear to improve the quality of life in deaf children. Researchers surveyed nearly 100 families of deaf children with cochlear implants, finding that the implants gave the children a quality of life equal to their peers, and that the earlier the device was implanted, the more likely the child was to experience these benefits.

CANCER VIDEO: Childhood Cancer Breakthrough, Children Respond to School Fitness Programs, Hospitalization and Cognitive Decline

Tue, 23 Feb 2010 19:00:00 EDT

(February 23, 2010 - Insidermedicine)

From Sweden - Scientists may have made a breakthrough in childhood cancer research, according to a report published in the Proceedings of the National Academy of Sciences. For 20 years, researchers studied 165 children with a type of childhood cancer that is particularly aggressive, known as neuroblastoma. Using novel genetic techniques, researchers were able to define the different DNA patterns of the neuroblastoma tumors.

From Switzerland - According to a report published online in the British Medical Journal, children's fitness improves with more school based activity programs. Researchers studied over 500 schoolchildren, randomizing one group to receive their standard physical education lessons and an intervention group to receive an additional two lessons designed by experts on top of their weekly routine. The intervention group showed better aerobic fitness, a relative decrease in body fat, and lower cardiovascular risk than the control group.

And finally, from Seattle - According to a report published in the Journal of the American Medical Association, hospitalized older adults are at increased risk of cognitive decline. Researchers studied nearly 3,000 adults 65 years and older; nearly 1300 were hospitalized during the study for non critical illness while 1600 were not hospitalized at all. Results showed that hospitalized patients had a 40% increased risk of later developing dementia.

ALZHEIMER'S VIDEO: Predicting Alzheimer's Disease Progression, Exercise Reduces Anxiety, Napping Good for the Brain

Mon, 22 Feb 2010 19:00:00 EDT

(February 22, 2010 - Insidermedicine)

From Texas - According to a report published in the journal Alzheimer's Research and Therapy, researchers have developed a way to reliably predict future progression of Alzheimer's disease. Studying nearly 600 patients for 15 years, researchers found that using several standardized tests to develop a progression rate prediction was successful in forecasting the speed at which Alzheimer's eventually developed.

From Georgia - Regular exercise may reduce anxiety, according to a report publisehd in the Archives of Internal Medicine. Researchers conducted a meta-anaylsis of 40 clinical trials covering almost 3,000 patients, finding that regular exercise resulted in a 20% reduction in anxiety symptoms.

And finally, from San Diego- According to a report presented at the annual meeting of the American Association of the Advancement of Science, napping may refresh the mind and help it learn better. Researchers had nearly 40 healthy adults undergo one learning task at noon and then another one at 6 pm, randomizing half to a 90 minute nap at 2 pm and the other half to stay awake during the day. Results showed that people who napped learned significantly more in the later session than those who stayed awake.

MULTIPLE SCLEROSIS VIDEO: Exercise Good for MS Patients, Green Tea May Protect Eyes, Postpartum Depression Common Among Low Income Urban Mothers

Fri, 19 Feb 2010 17:00:00 EDT

(February 19, 2010 - Insidermedicine)

From Ohio - According to a report published in the journal Brain Research, multiple sclerosis patients may benefit from exercise. Researchers compared 21 women with multiple sclerosis to 15 healthy controls, finding that the fitter the MS patient, the better they scored on cognitive functioning tests. MRI scans revealed that aerobic fitness had a protective effect on the specific parts of the brain damaged by MS.

From Hong Kong - According to a report published in the Journal of Agricultural and Food Chemistry, green tea may be able to protect against common eye conditions. Researchers gave lab rats green tea, finding that the antioxidants in green tea were indeed capable of passing from the stomach into eye tissues. As a result, the eye was temporarily relieved of oxidative stress.

And finally, from Rochester - Postpartum depression appears to be more prevalent among low-income urban mothers, according to a report published in the journal Pediatrics. Studying nearly 200 low income mothers whose children were under 14 months old, researchers found that 56% of participants had symptoms of minor or major depression.

HEAD INJURY VIDEO: Preventing Skiing and Snowboarding Head Injuries (Interview with Dr. Michael Cusimano, MD, PhD, St. Michael's Hospital)

Fri, 19 Feb 2010 17:00:00 EDT

(February 19, 2010 - Insidermedicine)

Skiers and snowboarders should take a tip from bikers and start making helmets the norm rather than the exception, according to a commentary published in the Journal of the American Medical Association.

While the effects of brain injuries vary depending on the precise area and type of damage, typical consequences include:

•    Memory loss

•    Impaired reasoning skills

•    Paralysis or loss of vision/hearing

Experts in neurosurgery from St. Michael's Hospital in Toronto are using cold, hard facts to encourage skiers and snowboarders to don helmets. They point out that head injuries are the leading cause of hospital admission and death related to these sports and that about 120,000 head injuries occur each year in North America alone among those engaging in them.

Wearing a helmet can reduce the risk of head injury by up to 60%, but the current culture among skiiers and snowboarders is not to wear them. The authors recommend some strategies for encouraging helmet use among the public. These include having snowboarders and skiers appearing in advertising wear helmets, having parents wear helmets to promote it among their children, and providing formal instruction on the importance of helmet-wearing at resorts, schools, and other groups.

Today's commentary indicates that the smart skiers and snowboarders, such as the Olympic contenders, wear helmets.

CANCER VIDEO: Cancer Researchers Identify Tumor DNA Red Flags, Sorafenib Shrinks Kidney Cancer Tumors, Obesity and Kidney Stone Risk

Thu, 18 Feb 2010 17:00:00 EDT

(February 18, 2010 - Insidermedicine)

From Baltimore - According to a report published in Science Translational Medicine, researchers have developed a new technique that may work to personalize cancer management. Scientists analyzed four colorectal and two breast tumors, finding that tumors DNA sequences had been uniquely rearranged. Researchers then used these rearranged DNA sequences as red flags--biomarkers capable of pointing towards other parts of the DNA that may have tumor DNA in them.

From North Carolina - The drug sorafenib has been shown to shrink kidney cancer tumors before surgery, according to a report published in the Journal of Clinical Oncology. Researchers studied 30 kidney cancer patients, administering sorafenib twice daily up to eight weeks before surgery. Results showed that the tumors shrunk up to 40% before the operation.

And finally, back to Baltimore - Obesity drastically raises ones risk of developing kidney stones, according to a report published in the Journal of Urology. Researchers reviewed data on nearly 100,000 people, finding that having a BMI of over 30kg/m2 nearly doubled the risk of having kidney stones.

MIGRAINE VIDEO: Chronic Migraines Increase Depression, Women Alcohol and Fatal Car Crashes, Happiness and Heart Disease Risk

Wed, 17 Feb 2010 19:00:00 EDT

(February 17, 2010 - Insidermedicine)

From New York – People who suffer from chronic migraines have worse general health and are more depressed than those who suffer migraines episodically, according to a report published in the Journal of Neurology Neurosurgery and Psychiatry. Researchers studied nearly 12,000 episodic and chronic migraine patients, finding that chronic migraine sufferers were 2x more likely to be depressed and experience chronic pain, 40% more likely to develop heart disease and 70% more likely to suffer stroke.

From Connecticut – According to a report published in Injury Prevention, alcohol has been connected to the increasing amount of fatal car crashes among women in the US. Reviewing US data on fatal car crashes from 1995-2007, researchers found that 3.2% of women involved in a fatal crash had a positive blood alcohol test, compared with only 1.2% of men.

And finally, back to New York – According to a report published in the European Heart Journal, people who are normally content, happy and joyful may have a decreased risk of heart disease. Researchers studied nearly 1,800 adults, measuring their levels of depression and anxiety, as well as the extent of ‘positive affect’—a host of emotions including joy, happiness, contentment, and enthusiasm. After controlling for age, gender and heart disease risk, results showed that the less positive affect a person had, the more likely they were to suffer heart disease.

INSIDERMEDICINE VIDEO: NSAIDs Do Not Reduce Skin Cancer Risk, Genetic Markers Fail to Predict Cardiovascular Disease, Autism Symptoms Gradually Develop

Tue, 16 Feb 2010 17:00:00 EDT

(February 16, 2010 - Insidermedicine)

From California - According to a report published in the Archives of Dermatology, non-steroidal anti-inflammataroy drugs do no appear to reduce skin cancer risk. Researchers compared 415 squamous cell carcinoma patients with 415 controls, finding that regular use of pain medications such as aspirin and ibuprofen resulted in no reduction in risk of squamous cell carcinoma.

From Boston - Using genetic markers to predict cardiovascular disease does not appear to be effective, according to a report published in the Journal of the American Medical Association. Researchers studied over 19,000 women for 12 years, constructing a risk score based on genetic markers known to be connected to CVD. They found that using the genetic risk score did not improve prediction of CVD.

And finally, back to California - According to a report published in the Journal of the American Academy of Child & Adolescent Psychiatry, symptoms of autism are not apparent in children under 6 months. Researchers compared 25 children at high risk for autism with 25 low risk children, finding that autism symptoms such as lack of eye contact, smiling and babbling only developed gradually over the first year of life and were not apparent at 6 months.

INSIDERMEDICINE VIDEO: MRI During Breast Cancer Assessment, Unfinished Treatment of PTSD in Most Soldiers, Type 2 Diabetic Women and Bone Fracture Risk

Fri, 12 Feb 2010 17:00:00 EDT

(February 12, 2010 - Insidermedicine)

From the UK - According to a report published in The Lancet, using MRI along with conventional breast cancer assessment does not decrease re-operation rates. Researchers studied 1623 breast cancer patients who were scheduled to undergo surgery after conventional triple assessment, randomizing half to undergo MRI and the other half to receive no further testing. Between the two groups, there was no noticeable difference in the amount of women who needed a repeat operation.

From San Francisco - According to a report published in the Journal of Traumatic Stress, many Americans soldiers suffering from posttraumatic stress disorder do not receive adequate treatment for the condition. Between 2002-2008, nearly 50,000 soldiers were newly diagnosed with PTSD. However, less than 10% of veterans actually complete their recommended treatment of 10-12 weekly sessions.

And finally, from Detroit - Women with type 2 diabetes taking thiazolidinedione have an increased risk of bone fractures, according to a report published in The Journal of Clinical Endocrinology & Metabolism. Researchers studied nearly 20,000 patients, finding that women taking TZD for one year had a 50% increased risk of suffering a bone fracture, though this relationship was not seen in men.

INSIDERMEDICINE VIDEO: Migraines and Heart Attack Risk, Shortened Radiation Therapy Successful, Milk While Pregnant May Decrease Child's Chances of MS

Thu, 11 Feb 2010 17:00:00 EDT

(February 11, 2010 - Insidermedicine)

From New York - According to a report published in the journal Neurology, migraines increase ones risk of suffering a heart attack. Researchers compared over 6,000 migraine sufferers with nearly 5,300 people without migraines. Results showed that people with migraine were nearly 2x more likely to suffer a heart attack than people without migraine.

From Hamilton - According to a report published in the New England Journal of Medicine, a shorter, more intense course of radiation therapy has been shown to be successful for women with early stage breast cancer. Researchers randomized over 1,200 breast cancer patients to either standard 5 week regimen of radiation therapy or an accelerated, 3 week regimen. Breast cancer recurrence rates after ten years were found to be similar for both groups.

And finally, from Minnesota - Women who drink milk during pregnancy may reduce their child's risk of developing multiple sclerosis later in life, according to a report presented at the annual meeting for the American Academy of Neurology. Researchers surveyed over 35,000 mothers and followed them for several years. They found that mothers who drank at least 4 glasses of milk a day during pregnancy had a 56% reduced risk of having their child develop MS.

INSIDERMEDICINE VIDEO: Gastric Bypass Works In Obese Teens, Medicated Glaucoma Patients Less Likely to Die, Patients With Unexplained Chest Pain Experience Little Relief

Tue, 9 Feb 2010 17:00:00 EDT

(February 9, 2010 - Insidermedicine)

From Australia - According to a report published in the Journal of the American Medical Association, obese teens who underwent gastric banding lost a significant amount of weight. Researchers studied 50 obese teenagers, some underwent gastric banding while others tool part in a lifestyle intervention program. They found that 84% of participants in the gastric banding group lost more than 50% of excess weight compared with only 12% of participants in the intervention group.

From Michigan - Glaucoma patients taking medication for the condition may have a decreased risk of mortality, according to a report published in the Archives of Ophthalmology. Researchers studied over 20,000 glaucoma patients for 4 years, finding that those on any kind of glaucoma medication were 74% less likely to die than those on no medication at all.

And finally, from Germany - A new study published in the Archives of Internal Medicine reveals that many patients suffering unexplained chest pain receive little relief from standard medical care. Researchers studied over 800 patients suffering from non-specific chest pain, finding that 55.5% still had chest pain six months after visiting a primary care office, and that 10.7% underwent unnecessary further testing.

INSIDERMEDICINE VIDEO: High Blood Pressure Possible Predictor of Dementia, Hazards of Third Hand Smoke, IBD Increases Blood Clot Risk

Mon, 8 Feb 2010 19:00:00 EDT

(February 8, 2010 - Insidermedicine)

From London - According to a report published in the Archives of Neurology, high blood pressure may be a predictor of dementia in some older adults. For five years, researchers studied nearly 1,000 elderly people suffering from cognitive impairment, but not dementia. They found that hypertension was associated with an increased risk of developing dementia in those adults who were unable to organize thoughts and make decisions, but not in those who suffered from memory dysfunction.

From California - A new report published in Proceedings of the National Academy of Sciences outlines the hazards of third hand smoke. Residual nicotine from burning tobacco attaches to almost every surface--lasting days, weeks and even months. Lab tests revealed that when this leftover nicotine interacted with a common ambient air pollutant nitrous acid, it created a carcinogen known as tobacco specific nitrosamines (TSNA).

And finally, from Nottingham - According to a report published in The Lancet, people suffering from inflammatory bowel disease face a significant increased risk of blood clots. Researchers compared over 13, 500 IBD patients with over 70,000 healthy controls. They found that non-hospitalized patients with active IBD were 16x more likely to suffer a blood clot when compared to non-hospitalized controls.

INSIDERMEDICINE VIDEO: Paroxetine Interferes With Life Saving Qualities of Breast Cancer Drug Tamoxifen (Interview with Dr. David Juurlink, Institute for Clinical Evaluative Sciences)

Mon, 8 Feb 2010 19:00:00 EDT

(February 8, 2010 - Insidermedicine)

Taking the antidepressant paroxetine interferes with the life-saving properties of the breast cancer therapy tamoxifen, according to research published in the British Medical Journal.

Here is some information about cancer and depression:

    •    An estimated 15 to 25% of cancer patients suffer from depression

    •    Depression associated with cancer can usually be treated with a combination of counseling and medication

    •    Depressed cancer patients should be evaluated by a professional for their risk of suicide

Researchers from Sunnybrook Odette Cancer Centre in Toronto and from the Institute for Clinical Evaluative Sciences (ICES) analyzed the long-term survival rates of nearly 2,500 Ontario women aged 66 and older who were treated with tamoxifen for breast cancer between the years 1993 to 2005. These women were also treated with one antidepressant of the SSRI class for some or all of the time they were taking tamoxifen.

Overall, about 30% of the women received antidepressant treatment while taking tamoxifen. After adjusting for factors that affect survival rates, including age, women who were taking paroxetine, which is also known under its tradename Paxil, while taking tamoxifen were more likely to die from breast cancer than those who had not taken this drug. The more paroxetine therapy overlapped with tamoxifen therapy, the higher the risk of dying from breast cancer. The authors estimate that using paroxetine for 41% of the duration of tamoxifen therapy would result in 1 additional death from breast cancer within five years for every 20 women treated. No association with breast cancer survival rates were found for other antidepressant.

We spoke with Dr. David Juurlink, one of the investigators of this study, who offered some further insight.

Today’s research suggests that women taking tamoxifen for breast cancer should not also take paroxetine. Never stop tamoxifen or paroxetine therapy without first consulting your health care professional

INSIDERMEDICINE VIDEO: Ultrasound Screening May Reduce Risk of Preterm Birth, HPV Vaccination Decreases Genital Diseases, Progesterone May Ward Off Preterm Birth

Fri, 5 Feb 2010 17:00:00 EDT

(February 5, 2010 - Insidermedicine)

From Chicago - Doctors can reduce the risk of preterm birth by conducting ultrasound screening for a short cervix, according to a report presented at the Annual Scientific Meeting of the Society for Maternal Fetal Medicine (SMFM). Researchers estimated the outcomes and costs of screening cervical length in all women--not just those at high risk for preterm birth. They found that such universal screening would actually reduce costs, improve quality of life and decrease neonatal deaths.

From Columbia - According to a report published in the Journal of the National Cancer Institute, HPV vaccination in young women may decrease occurrence of several genital diseases. Researchers studied over 17,000 15 year old women, finding that HPV vaccination resulted in a reduction in the risk of lesions, genital warts, abnormalities on pap smears, as well as the need for procedures such as colposcopy.

And finally, back to Chicago - According to another report presented at the Annual Scientific Meeting of the Society for Maternal Fetal Medicine, scientists may have identified the process by which the hormone progesterone wards off preterm birth. Many preterm births occur because the fetal membranes are weakened by apoptosis and then rupture. Researchers have found, however, that progesterone can inhibit apoptosis and thereby prevent preterm birth.

INSIDERMEDICINE VIDEO: Genetic Cause for Preterm Labor, COPD Raises Risk of Depression, BPA Exposure Increases Child's Chances of Asthma

Thu, 4 Feb 2010 17:30:00 EDT

(February 4, 2010 - Insidermedicine)

From Chicago - According to a report presented at the Annual Society for Maternal-Fetal Medicine meeting, genetics may cause some women to go into preterm labor. Researchers studied over 800 pregnant women--all of whom had a preterm birth prior to onset of the study-- and their fetuses. They found that the presence of a DNA variant in the fetus that influences inflammation doubled the risk of preterm birth, while certain variants in the mothers genes also raised this risk.

From Switzerland - COPD patients are more likely to suffer depression, according to a report published in the journal Chest. Comparing over 35,000 COPD patients with over 35,000 healthy controls, researchers found that the COPD patients had 6.8% higher prevalence of depression.

And finally, from Texas - According to a report published in the journal Environmental Health Perspectives, a mother's exposure to bisphenol A (BPA) raises her child's risk of developing asthma. Researchers gave mice BPA in their drinking water before pregnancy, during pregnancy and afterwards. They found that offspring of mice exposed to BPA demonstrated symptoms of asthma, while those who were not exposed showed no such signs.

INSIDERMEDICINE VIDEO: Possible Missing Gene in Morbidly Obese, Protein Levels in Urine and Reduced Kidney Function Raise Mortality Risk, Doctors and Diabetics Disagree on Priorities

Wed, 3 Feb 2010 17:15:00 EDT

(February 3, 2010 - Insidermedicine)

From London - According to a report published in the journal Nature, a significant amount of morbidly obese people are missing genes in their DNA. Researchers studied DNA samples of over 16,000 people, both obese and of normal weight. They found that 7 in every 1000 morbidly obese people shared a genetic deletion that was not found in any of those of normal weight. This genetic deletion becomes the second most frequent genetic cause of obesity.

From Calgary - According to a report published in the Journal of the American Medical Association, elevated levels of protein in the urine and reduced kidney function may lead to heart attack, kidney failure or death. Researchers studied data on over 900,000 individuals, analyzing measurements of protein in the urine as well as eGFR (a measurement of how well the kidney filters and removes waste). They found that all cause mortality risk was increased when patients had lower eGFR levels or higher proteinuria levels.

And finally, from Michigan - Diabetics prioritize their health concerns differently than their doctors, according to a report published in Journal of General Internal Medicine. Researchers surveyed almost 1,200 diabetic patients and 92 of their doctors, finding that 38% of the doctors ranked high blood pressure as the most important health concern for the patients, while only 18% of the patients agreed. The diabetic patients instead ranked pain and depression as their most important concern.

INSIDERMEDICINE VIDEO: Possible Biological Cause for SIDS, Internet Addiction Linked With Depression, Prostate Cancer Diagnosis Brings Immediate Risk of Suicide, Cardiovascular Death

Tue, 2 Feb 2010 19:00:00 EDT

(February 2, 2010 - Insidermedicine)

From Boston - Researchers believe that low serotonin production in the brain stem may cause sudden infant death syndrome (SIDS), according to a report published in the Journal of the American Medical Association. Taking samples from 36 infants who died of SIDS and comparing them with controls, researchers found that the SIDS cases had 26% lower serotonin levels in their brain stem.

From Leeds - According to a report published in the journal Psychopathology, too much internet use may lead to depression. Researchers studied over 1300 people aged 16-51, finding that 1.2% of participants developed an internet addiction. Of these addicts, there was a greater incidence of moderate to severe depression when compared with those who were not addicted.

And finally, back to Boston - According to a report published in the Journal of the National Cancer Institute, men diagnosed with prostate cancer are at immediate risk of both suicide and cardiovascular death. Researchers reviewed data over 340, 000 prostate cancer patients, finding an increased incidence of suicide and cardiovascular death in the first year following diagnosis.

INSIDERMEDICINE VIDEO: ADHD Linked To Lead Exposure, Improving Eating Skills in Dementia Patients Possible, Blood Test to Predict Rheumatoid Arthritis

Fri, 29 Jan 2010 17:00:00 EDT

(January 29, 2010 - Insidermedicine)

From Oregon - According to two studies published in the journal Current Directions in Psychological Science, ADHD may arise because of lead exposure. The first study found that children with ADHD had higher levels of lead in their blood, though researchers could only connect these blood levels with hyperactivity. The second study, however, found a clear connection between levels of lead in the blood and the parent's and teacher's assessment of ADHD, an assessment that included both hyperactivity and attention problems.

From Sheffield - According to a report published in the International Journal of Geriatric Psychiatry, researchers have found that it is possible to improve eating skills of dementia patients. Comparing two different step-by-step intervention methods with no intervention at all, researchers found that the two methods improved nutritional assessment and difficulty feeding scores in dementia patients.

And finally, from Sweden - A simple blood test may be able to predict rheumatoid arthritis even before symptoms develop, according to a report published in the journal Arthritis & Rheumatism. Researchers studied blood samples of over 80 people prior to developing RA symptoms, 69 of these people after they developed RA symptoms, as well as 256 controls. They found that elevation of cytokine levels in the blood predicted eventual development of rheumatoid arthritis.

INSIDERMEDICINE VIDEO: Smokers Endangered by Own Secondhand Smoke, Overweight Elderly May Be At Reduced Risk of Death, Symptoms Weak For Evaluation of Early Ovarian Cancer

Thu, 28 Jan 2010 19:00:00 EDT

(January 28, 2010 - Insidermedicine)

From Italy - People who smoke are also at risk from breathing their own secondhand smoke, according to a report published in the journal Environmental Health. Researchers studied the effects of second hand smoke on newsagents, following 15 active smokers who worked in their own newsstand and thereby were exposed only to their own smoke. They found that if someone was to smoke 14 cigarettes daily, inhaling their own secondhand smoke would be equivalent to smoking an extra 2.6 cigarettes.

From Australia - According to a report published in the Journal of The American Geriatrics Society, overweight adults over 70 years old actually have a reduced risk of death in a ten year period. Researchers examined over 9,000 men and women, aged 70-75 at the beginning of the study, for ten years. Results showed, surprisingly, that participants who had a BMI considered overweight had a 13% lower risk of death during the study than participants considered to be of normal weight.

And finally, from Seattle - According to a report published in the Journal of the National Cancer Institute, symptoms are largely ineffective in determining early ovarian cancer. Researchers compared over 800 patients with ovarian cancer to over 1300 healthy controls. They found that evaluating symptoms--including abdominal pain, frequent urination and bloating--would only be effective in detecting early stage ovarian cancer in about 1 in 100 women.

INSIDERMEDICINE VIDEO: Resting Boosts Memory, Schizophrenic Patients More Likely to Be Crime Victim, Rural Ontario Trauma Victims At Increased Risk of Death

Wed, 27 Jan 2010 19:00:00 EDT

(January 27, 2010 - Insidermedicine)

From New York - According to a report published in the journal Neuron, resting while awake may boost memory retention. Researchers showed participants several images and then put them in a period of awake rest--in which subjects could think about whatever they wanted to--while imaging a part of the brain that plays a role in memory known as the hippocampus. Results showed that during rest, there was significant activity in the hippocampus--and that those who had the most activity in that region scored better on consequent memory tests.

From Indianapolis - Many American schizophrenic patients becomes victims of crime, according to a report published in BMC Psychiatry. Researchers studied 600 schizophrenic patients, finding that 46% of these patients had at least one encounter with the criminal justice system and that in 67% of these cases, the schizophrenic patients were the victim of a crime.

And finally, from Toronto - According to a study published in the Journal of Trauma, a majority of trauma-related injuries that occur in rural Ontario, Canada result in pre-hospital patient mortality. Researchers studied nearly 3,500 trauma related mortalities that occurred in Ontario, finding 54% of trauma related deaths occurred before the patient even reached the emergency department. People who lived in the most rural locations, with little access to immediate trauma care centers, were twice as likely to die before reaching the hospital.

INSIDERMEDICINE VIDEO: Childhood Obesity Raises Risk of Heart Disease, UV Blocking Contact Lenses Good For Eyes, Pregnancy and Malaria Risk

Tue, 26 Jan 2010 17:00:00 EDT

(January 26, 2010 - Insidermedicine)

From Florida - Being obese by age 7 increases a child's risk of heart disease and stroke later in life, according to a report published in the Journal of Clinical Endocrinology & Metabolism. Researchers studied 202 children--115 of whom were obese and 87 who were lean controls--that had not yet developed symptoms of metabolic syndrome. Results showed that the obese children had abnormalities in their blood widely regarded as predictors for the development of heart disease, even though these children did not have risk factors such as high blood pressure.

From Ohio - According to a report published in the journal Investigative Ophthalmology & Visual Science, contact lenses that block ultraviolet radiation may protect eyes from the sun. Researchers exposed rabbits to the equivalent of roughly 16 hours of sunlight, finding that those who wore the UV blocking contact lenses experienced no damage to their corneas

And finally, from Liverpool- According to a report published in Public Library of Science Medicine, at least 125 million pregnancies are at risk of malaria each year. Researchers targeted certain territories in which malaria thrives, multiplying the number of pregnancies by the fraction of people living within the limits of malaria transmission in each country. Results showed that 125.2 million pregnancies--or, 60% of all pregnancies globally--were at risk of malaria every year.

INSIDERMEDICINE VIDEO: Abnormal Blood Pressure in Children of Pregnant Smokers, Blood Pressure Lowered with Low Carb Diet, Ambidextrous Kids At Raised Risk of ADHD

Mon, 25 Jan 2010 17:00:00 EDT

(January 25, 2010 - Insidermedicine)

From Sweden - According to a report published in Hypertension: Journal of the American Heart Association, mothers who smoke while pregnant increase their newborn's odds of having abnormal blood pressure. Researchers studied 19 children of non-smoking parents and 17 children of women who smoked during pregnancy, measuring blood pressure by having the infant tilted upright during sleep. At one week, results showed that newborns of mothers who smoked had a 10% increase in blood pressure when tilted, compared with only 2% increase in the non-smoking group.

From North Carolina - A low-carbohydrate diet may help lower blood pressure, according to a report published in the Archives of Internal Medicine. Researchers studied nearly 150 overweight people, administering either a low fat diet plus the weight-loss drug orlistat or a low carb diet. Results showed that 47% of patients in the low-carb group had their blood pressure medication either lowered or stopped altogether, compared with only 21% in the orlistat group.

And finally, from London - Children who are ambidextrous are more likely to suffer ADHD later in life, according to a report published online in the journal Pediatrics. Researchers followed nearly 8,000 children for 10 years, finding that children who were mixed handed by age 5 were 2x more likely to have ADHD symptoms in adolescence.

INSIDERMEDICINE VIDEO: Eating Less Salt Can Save Lives, Cognitive Difficulties In Childhood Linked to Schizophrenia Later in Life, H1N1 ICU Cases Described

Fri, 22 Jan 2010 17:00:00 EDT

(January 22, 2010 - Insidermedicine)

From California - Limiting the amount of salt in the diet can reduce risk of cardiovascular disease, according to a report published in the New England Journal of Medicine. Researchers used a computer model to estimate the impact that salt has on heart disease in the US. They found that reducing daily salt intake by 3 grams a day could potentially prevent 32,000 strokes and 54,000 heart attacks a year.

From North Carolina - According to a report published in the American Journal of Psychiatry, researchers may have found clues in childhood that may be linked to schizophrenia later in life. Studying over 1,000 children since 1972, researchers found that children who went on to develop schizophrenia in adulthood experienced certain cognitive difficulties by age 7--including problems with visual and verbal learning, difficulty reasoning and conceptualizing, and memory and attention problems.

And finally, from Manitoba - According to a report published in the Canadian Medical Association Journal, researchers underline the importance of prompt treatment of severe H1N1 symptoms. Studying all confirmed cases of H1N1 in Manitoba, finding that the longer the time between development of symptoms and treatment with antiviral medication, the more likely that person was to have severe disease that necessitated admission to ICU.

INSIDERMEDICINE VIDEO: Degree of Obesity Linked With Stroke Risk, ECG In the Field Lowers Mortality and Time to Treatment, Blood Test for Colorectal Cancer

Thu, 21 Jan 2010 17:00:00 EDT

(January 21, 2010 - Insidermedicine)

From Minnesota - The higher degree of obesity a person has, the more likely they are to suffer a stroke regardless of how the obesity is measured, according to a report published in the Stroke: Journal of the American Heart Association. Researchers studied over 13, 0 00 adults for 19 years, finding that patients in the highest BMI category had up to 2.12 times increased risk of stroke; those with the highest waist circumference had an increased risk of up to 3.19 times, and those with the highest waist-to-hip ratio saw their risk increase up to 2.55 times.

From Michigan - According to a report published in the journal Catheterization and Cardiovascular Interventions, giving chest pain patients an electrocardiogram before going to the hospital has significant benefits. Researchers studied two groups of patients with symptoms suggestive of a heart attack: one received an ECG in the field, and the data was sent electronically to the hospital so that ER physicians could interpret the data and prepare for the patients' arrival, while the control group had no prehospital ECG. Results showed that the ECG group had a lower mortality rate and a shorter time-to-treatment than the control group.

And finally from Orlando - According to a report presented at the ASCO GI Cancers Symposium, researchers may have developed a blood test that can detect early colorectal cancer. Testing for CD24 protein levels in one group of patients with colorectal cancer and in another group of healthy controls, researchers saw that the test had a 78% sensitivity and nearly 87% specificity at distinguishing between the two groups.

INSIDERMEDICINE VIDEO: Cladribine Shows Significant Benefit for MS Patients, Mild COPC Decreases Heart Function, HPV Testing Better than Paps at Preventing Cervical Cancer

Wed, 20 Jan 2010 17:00:00 EDT

(January 20, 2010 - Insidermedicine)

From the UK - A new drug has shown to significantly help people with multiple sclerosis, according to a report published in the New England Journal of Medicine. Researchers studied over 1300 MS patients for two years, administering the drug Cladribine or a placebo. Results showed that the Cladribine group had a 55% reduced risk of relapse and 30% reduced risk of deterioration of their disease.

From New York - According to another report published in the New England Journal of Medicine, even mild COPD has been shown to decrease heart functioning. Researchers studied nearly 3,000 adults, finding that even mild COPD--with little or no symptoms--was linked to a decreased ability of the heart to pump blood effectively.

And finally, from Italy - HPV DNA testing may be more effective at preventing cervical cancer than pap smears, according to a report published in the Lancet Oncology. Researchers studied data on 95,000 women, finding that those who were tested for HPV did not develop as many cancers as those who underwent only pap smears. These results, however, apply only to women over the age of 35--as HPV testing for women under 35 would likely lead to unnecessary treatment.

INSIDERMEDICINE VIDEO: Women in Labor Can Eat and Drink Normally, Concussions in Kids Not Taken Seriously Enough, Treadmill Helps For Parkinson's Patients

Tue, 19 Jan 2010 19:00:00 EDT

(January 19, 2010 - Insidermedicine)

From South Africa - According to a report published online in the Cochrane Library, women in labour should be allowed to eat and drink what they want. Researchers conducted an analysis of five studies covering over 3000 women, finding no risks or benefits from eating or drinking during labor. This research calls into question many maternity wards' "nil by mouth" policies, in which women in labor are restricted in what they can eat and drink.

From Hamilton - Concussions are not being taken as seriously as they should be, according to a report published in the journal Pediatrics. Researchers reviewed over 400 cases of children admitted to hospital with an acquired brain injury. Results showed that children who were diagnosed with a concussion were discharged from hospital earlier and returned to school earlier than children who were not diagnosed as having a concussion, an aspect that suggests that concussions are not widely regarded as the potentially serious brain injury that they may be.

And finally, from Germany - According to another report published online in the Cochrane Library, people suffering from Parkinson's disease may find their walking improved with treadmill training. Researchers looked at data from 8 studies, covering over 200 Parkinson's patients. They found that treadmill training had a positive impact on patient's stride, speed, steps per minute and gait.

INSIDERMEDICINE VIDEO: High Opioid Dose and Risk of Overdose, Mental Lapses May Be Sign of Alzheimer's, Texting More Dangerous than Drunk Driving

Mon, 18 Jan 2010 17:00:00 EDT

(January 18, 2010 - Insidermedicine)

From Seattle - According to a report published in the Annals of Internal Medicine, people suffering chronic pain that receive high doses of opioids face an increased risk of overdose. Researchers studied nearly 10,000 patients with opioid prescriptions, finding that those who were given a higher opioid dose had a nine-fold increased risk of overdose when compared to those with low doses.

From St. Louis - According to a report published in the journal Neurology, elderly people who are developing Alzheimer's disease are more likely to suffer cognitive fluctuations--a host of symptoms that include daytime sleepiness, disorganized thinking and mental lapses. Researchers surveyed over 500 elderly people with memory problems. They found that patients who suffered these mental lapses had a 4.6x increased risk of being diagnosed with Alzheimer's disease.

And finally, from the UK - Text messaging while driving may be more dangerous than drunk driving, according to a report presented by the RAC Foundation for Motoring. Researchers studied 17-24 year olds using a driving simulator, examining how text messaging affected their ability to operate the car. They found that steering control was dramatically reduced by 91% when texting and that reaction times also worsened by 35%-- compared with 12% longer reaction times when inebriated.

INSIDERMEDICINE VIDEO: End of Life Care Inadequate for Kidney Disease Patients, Green Tea Cuts Lung Cancer Risk, More Info Needed On Kidney Abnormalities

Fri, 15 Jan 2010 17:00:00 EDT

(January 15, 2010 - Insidermedicine)

From Alberta - According to a report published in the Clinical Journal of the American Society of Nephrology, end of life care for patients with chronic kidney disease is often inadequate. Researchers surveyed nearly 600 patients with late stage kidney disease. 61% said that they regretted the initiation of dialysis--maintaining that the treatment was often the doctors and family's choice, rather than their own. As well, most did not receive help in managing their pain nor did they receive psychological or emotional support.

From California - Green tea may have a protective effect against lung cancer, according to research presented at the Joint Conference for Molecular Origins of Lung Cancer. Researchers studied over 500 people, 170 who had lung cancer, 340 who were healthy controls. They found that people who drank at least one cup of green tea a day had 5x reduced risk of lung cancer, while past and present smokers had nearly 13x lower risk when compared to non green tea drinkers.

And finally, from Rochester - According to another report published in the Clinical Journal of the American Society of Nephrology, more information is needed regarding kidney abnormalities. Researchers examined nearly 2000 healthy potential kidney donors. They found that 1 in 4 of these people had an abnormality in their kidneys. Although these findings were not considered harmful, their long term effects were not clear.

INSIDERMEDICINE VIDEO: Importance of Dosing Antibiotics Based on One's Physical Characteristics (Interview with Dr. Matthew Falagas, Alfa Institute of Biomedical Sciences)

Fri, 15 Jan 2010 17:00:00 EDT

(January 15, 2010 - Insidermedicine)

Antibiotics and other drugs used to fight infections should be individually dosed based on patients' physical characteristics in order to maximize the drugs' effectiveness and safety, according to a Viewpoint argument made in the The Lancet.

Here is some information about antimicrobial drugs:

•    They are drugs used to kill germs, including bacteria and fungi, which can cause disease

•    Some microbes are developing resistance to antimicrobial drugs

•    Taking antimicrobial drugs only as prescribed by a health care professional can help diminish the threat of resistance

Researchers from the Alfa Institute of Biomedical Sciences in Athens provided many compelling reasons why antimicrobial drugs should be dosed based on patients' individuals characteristics instead of using the same dose for all adults. In the face of globalization and the worldwide epidemic of obesity, physicians today are likely to treat adults who vary dramatically in size and body composition from one another. At the same time, there is good evidence that the way antimicrobial drugs are broken down and cleared by the body can be heavily influenced by such characteristics as body size and the proportion of fat to lean body mass present. In addition, as the threat of drug-resistant germs increases, it is crucial that currently available antimicrobial drugs be used in a matter than maximizes their effectiveness.

An unresolved issue is exactly what body characteristics to take into account when determining the appropriate dose of an antimicrobial drug. Body weight, amount of lean body mass, amount of fat, and body surface area can all affect how a drug performs. It remains unclear which of these physical characteristics dosing adjustments should be based on.

We spoke with Dr Matthew E Falagas, one of the author's of the viewpoint, who offered some further insight.

Today's research suggests there is a need to move away from a "one size fits all" approach to dosing antimicrobial drugs and instead tailor the dose to the individual. Always follow your physicians' instructions carefully when taking antibiotics and other antimicrobial drugs.

INSIDERMEDICINE VIDEO: Retina Test for Alzheimer's, Elderly Women With Cognitive Impairment Get Unnecessary Mammograms, New Blood Test for Lung Cancer Accurate

Thu, 14 Jan 2010 17:00:00 EDT

(January 14, 2010 - Insidermedicine)

From London - According to a report published in the journal Cell Death & Disease, a new eye test could help produce an early diagnosis of Alzheimer's disease. The new technique, tested on animals, entails eye drops consisting of fluorescent markers that attach to the relevant retinal cells and highlight the ones that are dying. The retina is then imaged and this indicates the extent of brain cell death that occurs in neurodegenerative diseases such as Alzheimer's.

From San Francisco - According to a report published in the American Journal of Public Health, elderly women who suffer cognitive impairment are frequently given unnecessary mammograms. Researchers studied over 2,000 women aged 70 and older, finding that 18% of women with severe cognitive impairment received mammography screening. The problem, however , is that to benefit from screening one must have a life expectancy of 4-5 years, whereas the severely cognitively impaired women in this study had an average life expectancy of only 3.3 years.

And finally, from California - A new blood test may be able to accurately diagnose early stage lung cancer, according to research presented at the Joint Conference for Molecular Origins of Lung Cancer. Researchers studied 28 lung cancer patients and 56 controls--people who were at high risk for the disease--using a panel of 40 potential lung cancer biomarkers. Results showed that the blood test was 92% accurate at finding stage 1 lung cancer among controls.

INSIDERMEDICINE VIDEO: Ticalgrelor Reduces Mortality in Heart Attack Patients, Genetic Variant May Reduce Risk of Dementia, BPA Confirmed to Raise Risk of Heart Disease

Wed, 13 Jan 2010 18:30:00 EDT

(January 13, 2010 - Insidermedicine)

From Boston - According to a report published in The Lancet, the anti-clotting medication ticagrelor has proven to reduce mortality without consequently increasing bleeding in heart attack patients. Researchers studied nearly 13, 500 heart attack patients, randomizing some to ticagrelor and placebo and others to clopidogrel and placebo for six months following hospitalization. Results showed that the ticagrelor group had a 16% reduced risk of suffering either cardiovascular death, myocardial infarction or stroke when compared to the clopidogrel group.

From New York - Scientists have discovered a genetic variant that may be associated with a lower risk for dementia, according to a report published in the Journal of the American Medical Association. Researchers studied 523 adults aged 70 and older, finding that those who had two copies of the CETP longevity variant had a 72% reduced risk of eventually developing dementia during the 4.3 years of the study.

And finally, from England - According to a report published in the journal PLoS ONE, new research has confirmed that BPA--or bisphenol A--is linked with an increased risk of cardiovascular disease. Researchers studied nearly 1500 patients, finding that those who had the highest urinary concentration of BPA--a chemical compound that is used in baby bottles, food cans and water containers--were 33% more likely to suffer heart disease.

INSIDERMEDICINE VIDEO: Loss of Smell Possible Predictor of Alzheimer's, Family History of Pancreatic Cancer Increases Risk, Excessive TV May Shorten Life

Tue, 12 Jan 2010 17:00:00 EDT

(January 12, 2010 - Insidermedicine)

From New York - Scientists believe that loss of smell may be a predictor of Alzheimer's disease, according to a report published in the Journal of Neuroscience. Studying mice genetically engineered to develop amyloid plaques in their brains, researchers noted that the mice with the highest concentration of amyloid sniffed items longer in order to identify them and also had difficulty discerning between odors. Researchers attributed these changes to the fact that the amyloid plaques first developed in a part of the mouse's brain that is also directly above their nose and responsible for smelling.

From Baltimore - According to a report published in the Journal of the National Cancer Institute, family history of pancreatic cancer significantly increases ones risk of also developing the disease. Researchers studied data on over 9,000 people from 1700 families. They found that a person has a sixfold raised risk of pancreatic cancer if one has multiple family members with the disease, while those who had a relative under 50 with pancreatic cancer were at a 9x increased risk.

And finally, from Australia - According to a repot published in the journal Circulation: Journal of the American Heart Association, excessive television watching may shorten ones lifespan. Researchers followed nearly 9,000 adults for six and a half years, finding that those who watched four or more hours of TV each day had a 46% increased risk of dying during the study when compared with those who watched less than two hours daily.

INSIDERMEDICINE VIDEO: C Sections Only When Indicated, Predictor of Success in Cornea Transplant Surgery, Even Low Levels of Lead Bad for Children's Kidneys

Mon, 11 Jan 2010 18:30:00 EDT

(January 11, 2010 - Insidermedicine)

From Switzerland - According to a report published in The Lancet, cesarean sections should not be done unless medically indicated. Researchers from the World Health Organization examined data on over 100 000 deliveries, finding an increased risk of both morbidity--admission to intensive care, hysterectomy and blood transfusion--and maternal mortality associated with cesarean sections that were not medically indicated.

From Ohio - Researchers have identified a new predictor of success in cornea transplant surgery, according to a report published in the Archives of Ophthalmology. Previous theories maintained that the donor's endothelial cells--the cells that line the underside of the cornea--would predict whether the transplant would succeed or not. New research, however, shows that the patient's endothelial count six month after transplantation is much better at predicting the eventual success of the procedure.

And finally, from Baltimore - According to a report published in the Archives of Internal Medicine, even a tiny amount of lead in the blood can be dangerous for children's kidneys. Researchers studied nearly 800 children and teenagers, finding that children with lead levels above 2.9 micrograms per deciliter had a kidney filtration rate that was 6.6 units lower than children who had less than 1 micrograms per deciliter in their blood.

INSIDERMEDICINE VIDEO: Exercise Helps Stave Off Cognitive Impairment In Elderly Women (Interview with Dr. Yonas Geda, MD, Mayo Clinic)

Mon, 11 Jan 2010 18:30:00 EDT

(January 11, 2010 - Insidermedicine)

A moderately intensive exercise routine can help stave off cognitive impairment, while intense exercise may help improve cognitive impairment that has already begun, at least among women, according to two studies published in the Archives of Neurology.

Here is some information about mild cognitive impairment:

•    it is a transition stage between the cognitive decline that occurs with normal aging and dementia seen in conditions such as Alzheimer's disease

•    it can affect memory as well as reasoning, judgment, language, and attention

•    while the condition may remain stable, many of those with mild cognitive impairment will go on to develop more serious symptoms

In the first study, researchers from the University of Washington School of Medicine and Veterans Affairs Puget Sound Health Care System in Seattle randomly assigned over 30 adults aged 55 to 85 with mild cognitive impairment to partake in a high-intensity aerobic exercise regimen or a stretching regimen. The aerobic group worked out with a professional to within 75 to 85% of their maximum heart rate for 45 to 60 min 4 days a week. After six months, both men and women in the aerobic group were more fit. The women in this group also enjoyed significant improvement in their cognitive ability. This improvement was much less marked in men, possibly due to sex differences in the metabolic effects of exercise.

In the second study, researchers from the Mayo Clinic in Rochester compared the exercise habits of nearly 200 older adults with mild cognitive impairment with those of over 1,000 older adults without the condition. Their analysis revealed that exercising moderately reduced the risk of having mild cognitive impairment in mid life by 39% and in late life by 32% in both men and women. Interestingly, neither light nor intense exercise had this effect.

Today's research suggests that engaging in at least a moderately intensive exercise routine can help keep your brain sharp as you age.

INSIDERMEDICINE VIDEO: TB Risk Decreases With Additional Birth Weight, Atherosclerosis Risk For HIV Infected Men, New Discovery in Fight Against Cancer

Fri, 8 Jan 2010 17:00:00 EDT

(January 8, 2010 - Insidermedicine)

From Michigan - According to a report published online in the Journal of Infectious Diseases, every additional pound at birth lowers a newborns risk of developing tuberculosis. Studying identical twins, researchers found that for every 1.1 pounds of birth weight, TB risk decreased by 87% for males and 16% for females.

From Massachusetts - Men infected with HIV who have minimal cardiac risk factors nonetheless have been found to suffer from serious atherosclerosis, according to a report published in the journal AIDS. Researchers studied 110 men--78 of whom had HIV while 32 were healthy controls--with no symptoms of cardiovascular disease. Results of CT angiography showed coronary atherosclerosis in 59% of HIV patients, compared with 34% of controls. As well, five of the HIV patients had critical coronary stenosis compared with none of the controls.

And finally, from Montreal - According to a report published in the journal Science Signalling, scientists have identified a connection between two genetic pathways that may help in the fight against cancer. Researchers discovered a link between the gene PTEN--which is known to suppress tumors--and the protein PKR--known to hinder protein synthesis. They found that, when the gene PTEN is either missing or mutated, PKR no longer stops protein synthesis, thereby setting the stage for tumor development. This discovery could potentially lead to new cancer treatments aimed at activating the PKR protein.

INSIDERMEDICINE VIDEO: Abnormal Blood Calcium Levels Linked With Death Risk, Pediatric Cancer Survivors More Likely to Get Heart Disease, Obesity As Bad As Smoking

Thu, 7 Jan 2010 19:00:00 EDT

(January 7, 2009 - Insidermedicine)

From Virginia - Kidney disease patients with either high or low blood calcium levels are increased risk of premature mortality, according to a report published in the Clinical Journal of the American Society of Nephrology. Researchers analyzed over 1200 males suffering from chronic kidney disease but who did not need dialysis. They found that patients with unusually high blood calcium levels were at 31% increased risk of death, while those with unusually low levels saw their risk increase by 21%.

From Philadelphia - According to a report published in the journal Cancer Epidemiology, Biomarkers & Prevention, childhood cancer survivors are more likely to develop several health conditions that consequently raise their risk of heart disease. Researchers examined information on over 8,500 pediatric cancer survivors and nearly 3,000 of their siblings. They found that survivors were 70% more likely to have diabetes than their siblings, 60% more likely to be taking a medication for cholesterol, and 2x more likely to be on medication for hypertension.

And finally, from New York - Obesity is now considered as big a health threat as smoking, according to a report published in the American Journal of Preventive Medicine. The 15 year study focused on quality adjusted life years (QALY)--a measurement of both quantity and quality of life, in regards to health. Though smoking was found to cause more mortality, obesity--which rose 85% over the course of the study--was found to have caused more disease.

INSIDERMEDICINE VIDEO: Cell Phones May Reduce Alzheimer's Risk, Coffee Linked With Less Likelihood of Liver Fibrosis, Childhood Abuse and Migraines Connected

Wed, 6 Jan 2010 18:00:00 EDT

(January 6, 2010 - Insidermedicine)

From Florida - According to a report published in the Journal of Alzheimer's Disease, long term exposure to cell phones may have a protective effect against Alzheimer's disease. Researchers studied nearly 100 mice that were genetically engineered to have brain plaques, exposing them to electromagnetic waves from a cell phone. Results showed that beta-amyloid proteins were eliminated thereby erasing the brain plaques, while exposure in younger mice actually prevented the buildup of these proteins.

From Bethesda - Caffeine may decrease liver fibrosis risk in chronic liver disease patients, according to a report published in the journal Hepatology. Researchers surveyed nearly 200 patients scheduled for a liver biopsy, finding that those who drank roughly 2.25 cups of coffee daily-or 308 mg of caffiene--had a 75% reduced risk of suffering advanced fibrosis.

And finally, from Ohio - According to a report published in the journal Headache: The Journal of Head and Face Pain, children who are emotionally or physically abused are more likely to suffer migraines and pain disorders later in life. Researchers surveyed nearly 1,400 migraine patients, finding that participants who reported emotional abuse or neglect in childhood had a higher rate of comorbid pain conditions than those who did not suffer this abuse.

INSIDERMEDICINE VIDEO: Leptin and Diabetes Reversal, Smoking Past 80 Increases AMD Risk, Nurse Visits Linked With Decreased Criminal Problems In Youth

Tue, 5 Jan 2010 17:00:00 EDT

(January 5, 2010 - Insidermedicine)

From New York - According to a report published in the journal Cell Metabolism, the hormone leptin appears to control a gene that may have significant anti-diabetes effects. Previous research has demonstrated an association between leptin and diabetes reversal, however, researchers did not know whether these effects were because of the hormone itself or because of the hormone's ability to reduce body weight. However, scientists have now discovered that leptin controls a gene called IGFBP2--a gene that, when increased in obese and diabetic mice, reversed the rodent's diabetes without inducing weight loss.

From California - Smoking past age 80 significantly raises ones risk of age related macular degeneration, according to a report published in the American Journal of Ophthalmology. Researchers studied nearly 2,000 women taking part in a long term study. They found that smokers who were 80 years or older had 5.5 times increased risk of developing AMD than those of the same age who did not smoke.

And finally, back to New York - Home visits by a nurse during and after pregnancy may help keep female children out of jail later in life, according to a report published in the Archives of Pediatric and Adolescent Medicine. Researchers followed 400 families in a 27 year study, comparing a group of mothers who received prenatal and infancy home nurse visits with a group that did not. While 30% of girls in the group who did not receive nurse visits were arrested by age 19, only 10% of girls in the group who did receive visits were arrested.

INSIDERMEDICINE VIDEO: Quitting Smoking Increases Risk of Diabetes, Americans With Depression Not Treated Properly, New Protein Targeted in Fight Against Breast Cancer

Mon, 4 Jan 2010 17:00:00 EDT

(January 4, 2010 - Insidermedicine)

From Baltimore - Quitting smoking may result in an increased risk of developing type 2 diabetes, according to a report published in the Annals of Internal Medicine. Researchers studied nearly 11,000 adults for 17 years. Results showed that those who quit smoking were 70% more likely to develop type 2 diabetes within six years than those who had never smoked, an aspect that indicates the importance of weight control following smoking cessation and the importance of never smoking.

From Detroit - According to a report published in the Archives of General Psychiatry, most Americans suffering from major depression do not receive adequate treatment for the condition. Researchers personally surveyed over 15,000 adults, finding that even though half of participants with depression received at least one form of therapy, only 21% actually received a form of therapy that met treatment guidelines.

And finally, from Michigan - Scientists may have discovered a new target in the fight against breast cancer, according to a report published in the Journal of Clinical Investigation. Researchers studied human breast cancer stem cells in vitro, targeting the protein known as CXCR1 with an antibody. Results showed a decrease in cancer stem cells as well as the death of many remaining tumor cells.

INSIDERMEDICINE VIDEO: Environmental Factors in Skin Aging, Operating Room Strategies, Virus Fighting Proteins Identified

Mon, 21 Dec 2009 19:00:00 EDT

(December 21, 2009 - Insidermedicine)

From Cleveland - It is estimated that up 40% of skin aging is related to environmental factors. According to an analysis of 65 twin pairs, smoking, being overweight and not using sunscreen raise the risk of premature skin aging. The research, published in the Archives of Dermatology, also suggests that drinking alcohol may prevent premature skin aging.

From Providence - According to research published in the Archives of Surgery, surgeons who run their ORs like a aviation cockpit may make surgical error less likely. Based on lessons learned from the aviation industry, surgical teams from Brown University implemented a series of checklists to improve communication and reduce errors. The process has resulted in 100% compliance and an improved feeling of self-empowerment among staff.

And finally, from Boston - A new family of proteins has been identified that may lower the risk of getting the flu and may one day help in treating other viral infections. A research team from Harvard, studying human and mouse cells, identified the flu-fighting proteins that slowed most virus particles, including the H1N1 virus from infecting cells at the earliest stage in the virus lifecycle.

INSIDERMEDICINE VIDEO: Alcohol Outlets Play Role in Alcohol Problems of Young Adults, Smoking Mutates DNA, New Blood Clotting Agent to Help Wounded Soldiers

Fri, 18 Dec 2009 17:00:00 EDT

(December 18, 2009 - Insidermedicine)

From California - According to a report published in the journal Alcoholism: Clinical & Experimental Research, underage and young adults may have more alcohol related problems depending on the amount and type of alcohol outlets that surround them. Researchers examined hospital discharge information, as well as demographic data regarding alcohol outlets, focusing on youth aged 18-20 and 21-29. They found that greater numbers of restaurants were associated with more traffic accidents and greater numbers of bars were associated with more assault injuries.

From the UK - Scientists have found that smoking can mutate a person's DNA, according to a report published in the journal Nature. A large international study identified almost 23,000 genetic mutations in lung cancer cells. As a result, researchers estimate that people attain one genetic mutation for every 15 cigarettes smoked--emphasizing that every time these mutations occur, they have a chance to 'hit' a cancer gene.

And finally, from Cleveland - According to a report published in the journal Science Translational Medicine, scientists have developed a new blood clotting agent that may help soldiers wounded in combat. Researchers developed synthetic platelets that, once injected into the patient, combine with natural platelets to form a blood clot and stop the bleeding. When injected in rats 20 seconds following an injury, bleeding time was reduced by 25%.

INSIDERMEDICINE VIDEO: In Hospital Kidney Injury Increases Risk of Mortality, Cutting TV Time Burns Calories in Overweight People, Natural Antiviral Protein Discovered

Thu, 17 Dec 2009 19:00:00 EDT

(December 17, 2009 - Insidermedicine)

From Massachusetts - Suffering an acute kidney injury (AKI) in-hospital increases a patient's risk of mortality once released, according to a report published in the Journal of the American Society of Nephrology. Researchers studied over 83,000 patients who suffered sudden loss of their kidney function in-hospital, but did not undergo dialysis and survived a minimum of three months after their release from the hospital. Results showed that 30% of patients who suffered AKI died after two years, compared with only 16% of patients who did not suffer this injury.

From California - According to a repot published in the Archives of Internal Medicine, watching less television burns calories in overweight adults. Researchers studied 36 overweight adults, having one group of participants cut their TV time in half while the other watched their normal amount. Results showed that the group of patients who watched less TV burned an extra 120 calories per day.

And finally, back to Massachusetts - Researchers have identified naturally occurring proteins that help prevent viral infections, according to a report published in the journal Cell. Researchers found antiviral proteins in human and mouse cells, discovering that the proteins were able to either prevent or at least slow viruses--such as the seasonal flu, H1N1 influenza, West Nile virus, and the dengue virus--as soon as the infection started its course.

INSIDERMEDICINE VIDEO: Less Education Linked to More Asthma Problems, FDA Recommends Preventive Use of Rosuvastatin, Nearsightedness On the Rise

Wed, 16 Dec 2009 19:00:00 EDT

(December 16, 2009 - Insidermedicine)

From Montreal – According to a report published in the journal Respiratory Research, researchers may have found a connection between education level and problems with asthma. Researchers studied over 800 adult patients, finding that those with less than 12 years of formal schooling were more likely to have worse control over their asthma symptoms as well as a 55% increased risk of going to the emergency department with an asthma related incident.

From Washington – The FDA is now recommending that rosuvastatin can be used for preventive purposes, even in patients with no history of atherosclerosis. Researchers studied over 17,000 adult men and women who had no prior history of heart disease but had elevated c-reactive protein levels, administering rosuvastatin for nearly 2 years. Results showed a relative decrease of 44% in the amount of heart attack, stroke, and cardiovascular death.

And finally, from Bethesda – According to a report published in the Archives of Ophthalmology, the amount of people with nearsightedness has increased significantly in the past 30 years. Researchers examined information from the National Health and Nutrition Examination survey (NHANES), comparing the prevalence of nearsightedness (or, myopia) from 1971-1972 with 1999-2004. They found that the overall incidence of myopia increased from 25% in the earlier period to 41.6% in the later period.

INSIDERMEDICINE VIDEO: Low Leptin Levels Linked to Alzheimer's Disease, Cystic Fibrosis Decreases with More Screening, Insomnia Connected to Childhood Medical Presentation

Tue, 15 Dec 2009 17:00:00 EDT

(December 15, 2009 - Insidermedicine)

From Boston - According to a report published in the Journal of the American Medical Association, high leptin levels may be associated with a lower risk of Alzheimer's disease. Researchers measured leptin levels of over 700 healthy patients at the beginning of the study, 198 of whom underwent brain MRIs 7 years later. Results showed that those with the lowest leptin levels had an absolute risk of 25% for Alzheimer's, while those with the highest levels had a risk of only 6%.

From Italy - According to another report published in the Journal of the American Medical Association, researchers have noted an association between increased cystic fibrosis carrier screening and decreased newborns who have the condition. Researchers studied two Italian regions for 14 years; one had a limited CF screening program of only relatives of CF patients and couples undergoing in vitro fertilization, while the other was more comprehensive and screened infertile couples as well as couples who were of reproductive age. Results showed that the comprehensive screening region had a much more significant decrease in neonates born with CF than the region with limited screening.

And finally, from Pennsylvania - Young children presenting with headaches and gastrointestinal regurgitation frequently have insomnia symptoms as well, according to a report published in the Journal of Clinical Sleep Medicine. Researchers analyzed 700 children between 5 and 12 years old, surveying their parents on how the child slept. Results showed that children with gastrointestinal regurgitation were 3.3 times more likely to have symptoms of insomnia, while children with headaches were 2.3 times likely to suffer these symptoms.

INSIDERMEDICINE VIDEO: Brain Plaques May Be Predictor of Alzheimer's, Protein Discovered that Helps Prevent Liver Cancer, Antidepressants Linked With Stroke, Death Risk

Mon, 14 Dec 2009 17:00:00 EDT

(December 14, 2009 - Insidermedicine)

From St Louis - According to a study published in the Archives of Neurology, the presence of brain plaques in an otherwise healthy person may be a predictor of Alzheimer's disease later in life. For four years, researchers studied 150 adults aged 51 to 88, using positron emission tomography to image participant's brains. Over the course of the study, results showed that those who scanned positive for brain plaques would go on to demonstrate signs of mental impairment and a diagnosis of Alzheimer's, while those who scanned negative for plaques did not develop these problems.

From San Diego - Scientists have discovered a protein that works to prevent liver cancer, according to a report published in the journal Proceedings of the National Academy of Science. Researchers made a mouse model that lacked the TAK1 protein--a sort of 'switch' that signals other proteins that help keep liver cells from dying and thereby provide protection against cancer. They found a significantly high rate of liver cell death in these mice--as their livers overcompensated for the missing protein and consequently produced too many liver cells thereby leading to inflammation and cancer.

And finally, from Washington - According to a report published in the Archives of Internal Medicine, antidepressants use in postmenopausal women is associated with an increased risk of stroke and death. Researchers examined data on over 160,000 women, finding that those who took antidepressants had an 45% increased risk of stroke and a 32% increased risk of death, though the overall risk of both were quite small.

INSIDERMEDICINE VIDEO: Cancer Fighting Molecule Discovered, Weight Loss Improves Hearts of Obese People, Molecule May Be Able to Slow ALS

Fri, 11 Dec 2009 17:00:00 EDT

(December 11, 2009 - Insidermedicine)

From Montreal - Scientists have discovered a molecule that provides a natural defense against cancer, according to a report published in the journal Molecular Cell. Researchers found that the SOCS1 molecule works to prevent cancer by impeding the excessive activity of cytokines that is seen with the disease. The researchers also found that reintroducing the SOCS1 molecule into tumor cells precluded the cells from multiplying, thereby rendering the cancer dormant.

From St. Louis - According to a report published in the Journal of the American College of Cardiology, obese people can improve their heart function with even moderate weight loss. Researchers studied 60 obese patients for two years, subjecting the participants to low calorie diets and roughly 3 hours of exercise per week. Results showed that participants hearts were able to pump and relax better, and that their carotid artery walls and the heart muscle itself both decreased in thickness.

And finally, from Texas - Researchers have found a naturally produced molecule that may help delay progression of amyotrophic lateral sclerosis (or, Lou Gehrig's disease), according to a report published in the journal Science. Researchers discovered that the molecule microRNA-206 is produced by skeletal muscle as a response to nerve damage, pushing healthy nerves to send new 'branches' towards those nerves that have been affected, temporarily regenerating them. The molecule was shown to limit ALS symptoms and even lengthen life in a mouse model.

INSIDERMEDICINE VIDEO: Health Canada Issues Warning Over Acai Berry Products, New Avenue for Blood Clot Treatments, Alcohol Raises Risk of Breast Cancer Recurrence

Thu, 10 Dec 2009 19:00:00 EDT

(December 10, 2009 - Insidermedicine)

From Ottawa - Canadians should be wary of taking certain acai berry products, according to a warning from Health Canada. The warning comes following the discovery that shipments of acai berry products crossing the Canadian border were found to contain sildenafil--a medication for erectile dysfunction. Sildenafil should not be taken unless supervised by a doctor, as it is a prescription medication and people with heart problems may be at increased risk of stroke and heart attack should they take the drug.

From Leeds - According to a report published in the journal Cell, researchers may have found a new approach to treating blood clots. Currently, most patients with blood clots are treated with the anticoagulant Warfarin--a medication that thins the blood but also puts the patient at risk of excessive bleeding if they get injured. Researchers have now discovered, however, that the molecule polyphosphate contributes to the blood clot in the artery without adversely affecting the patient's wound healing ability--a discovery that could make the molecule a new target in blood clot treatments.

And finally, from California - Moderate alcohol consumption significantly increases a woman's risk for breast cancer recurrence, according to research presented at the 2009 San Antonio Breast Cancer Symposium. Researchers studied nearly 1,900 breast cancer survivors for eight years. They found that three to four alcoholic drinks per week, regardless of the type, increased breast cancer recurrence risk by 30%, with obese women and postmenopausal women at the greatest risk.

INSIDERMEDICINE VIDEO: Process Can Reverse Sickle Cell Disease Damage, Solid Foods and Food Sensitivity, Bone Marrow Cell Procedure For Heart Attack Patients

Wed, 9 Dec 2009 17:00:00 EDT

(December 9, 2009 - Insidermedicine)

From Baltimore – According to a report published in the New England Journal of Medicine, scientists may have discovered a way to reverse severe sickle cell disease in adults. Researchers studied 10 patients with severe sickle cell disease, administering an IV transplant of blood forming stem cells from healthy donors along with the drug rapamcyin. Results showed that 90% of these patients had normal red blood cells and consequently saw their organ damage reversed.

From Finland – According to a report published in the journal Pediatrics, delayed introduction of solid foods into an infant’s diet may lead to food allergies later in life. Researchers reviewed data on nearly 1000 children who took part in a large birth cohort study. They found that late introduction (defined as 6 months) of eggs, wheat and oats into the child’s diet had a significant association with food sensitivity at age 5.

And finally, from Germany – Bone marrow cells may be able to reduce patients risk of suffering a second heart attack, according to a report published in the journal Circulation: Heart Failure. Researchers randomized over 200 heart attack survivors who had undergone stent placement to either an infusion of progenitor cells from their own bone marrow into the damaged artery or a placebo solution. Results showed that none of the bone marrow infusion group suffered a second heart attack compared with 7 in the placebo group, a difference deemed statistically significant

INSIDERMEDICINE VIDEO: Child Cancer Survivors At Increased Risk of Heart Disease, Newborn Screening Test for Lymphopenia, Pistachios May Reduce Risk of Lung Cancer

Tue, 8 Dec 2009 19:00:00 EDT

(December 8, 2009 - Insidermedicine)

From Minnesota - According to a report published in the British Medical Journal, pediatric cancer survivors are at increased risk of heart disease as young adults. Researchers compared over 14, 000 cancer survivors taking part in a long term study with nearly 4,000 of their siblings. Results showed that childhood cancer survivors were more likely to develop heart failure, heart attacks, and heart inflammation in young adulthood. This risk was apparent even up to 30 years following cancer treatment.

From Wisconsin - DNA screening of newborns is able to detect T-cell lymphopenia, according to a report published in the Journal of the American Medical Association. Researchers screened over 70,000 samples of newborn blood screening cards. They found that screening the amount of T-cell receptor excision circles (TREC) in the blood was able indicate whether or not the child suffered from T-cell lymphopenia (low levels of white blood cells).

And finally, from Houston - A daily dose of pistachios may be able to reduce risk of lung cancer, according to a report presented at the American Association for Cancer Research Frontiers in Cancer Prevention Research Conference. Researchers divided 36 participants into two groups: one ate 68 grams of pistachios a day while the other maintained their normal diet. Results showed that the pistachio group had a significant rise in their amount of gamma-tocopherol--a form of Vitamin E that is known to provide some protection against lung cancer.

INSIDERMEDICINE VIDEO: Genetic Cause For Some Obesity, New Drug For Cystic Fibrosis, Venous Thromboembolism Treatment

Mon, 7 Dec 2009 20:00:00 EDT

(December 7 - Insidermedicine)

From Cambridge (UK) - According to a report published in the journal Nature, genetic mutations, known as copy number variants (where sections of DNA are deleted or duplicated), have been identified as a cause of severe childhood obesity. The researchers examining 300 severely obese children found that some of these children were missing sections of chromosome 16. They believe that a specific gene on this chromosome, SH2B1, plays a role in regulating weight and blood sugar.

From California - Researchers have found a compound that may restore some lung function in those who suffer from cystic fibrosis, according to a report published in the online edition of Nature Chemical Biology. The drug suberoylanilide hydroxamic acid (SAHA), originally used to treat lymphoma, was able to restore 28% of normal lung cell function in cells taken from cystic fibrosis patients. While further research is necessary, this may one day ease the symptoms and improve the quality of life of those who suffer from cystic fibrosis.

And finally, from Hamilton - A more convenient oral medication for those with the clotting disorder venous thromboembolism may soon be available. VTE is usually treated with the blood thinner warfarin, which requires patients to carefully watch their diet and has known interactions with other drugs. According to a new report published online by The New England Journal of Medicine, dabigatran etexilate is as safe and effective as warfarin, without the need for such careful monitoring or dose adjustment.

INSIDERMEDICINE VIDEO: Childhood Cancer Survival Rates, Cell Phones Do Not Cause Brain Tumors, Cannabis Helpful for MS Symptoms

Fri, 4 Dec 2009 17:00:00 EDT

(December 4, 2009 - Insidermedicine)

From Atlanta – Certain childhood cancers are more likely to recur, according to a report published in the Journal of the National Cancer Institute. Analyzing data from the Childhood Cancer Survivor Study in which over 12,000 pediatric cancer survivors were evaluated, researchers found that the overall cancer recurrence rate was 4.4% at 10 years, and 6.2% at 20 years. However, ewing sarcomas had a recurrence rate of 13% at 20 years and astrocytoma had a recurrence rate of 14.4% after 20 years.

From Denmark - Researchers have been unable to connect cell phone usage to the development of brain tumors, according to another report published in the Journal of the National Cancer Institute. Using information from 4 Scandinavian countries, researchers found no significant difference in brain tumor rates from 1974 to 2003. Though there was an increase in meningioma occurrence among women, most of this increase was attributed to women over the age of 60--a group not considered to be heavy cell phone users.

And finally, from Los Angeles – Cannabis may be helpful for patients with multiple sclerosis, according to a report published in the journal BMC Neurology. Researchers reviewed several controlled trials analyzing effects of cannabis extracts on MS symptoms. 5 out of 6 of these trials noted that cannabis use resulted in improvements in mobility as well as a reduction of spasticity (a symptom in which the central nervous system tells muscles to contract or tense up).

INSIDERMEDICINE VIDEO: Smoking Linked to Colorectal Cancer Risk, Gene Connected to Medulloblastoma Identified, Secondhand Smoke Exposure Raises Risk of Breast Cancer

Thu, 3 Dec 2009 19:00:00 EDT

(December 3, 2009 - Insidermedicine)

From Philadelphia - According to a report published in the journal Cancer Epidemiology, Biomarkers & Prevention, scientists have identified a strong connection between cigarette smoking and colorectal cancer. For 13 years, researchers followed over 180,000 people aged 50-74. They found that people who smoked for more than 40 years had up to a 50% raised risk of developing either colon or rectal cancer.

From Texas - Scientists have pinpointed a gene linked to medullobalstoma, according to a report published in the journal Science. Researchers genetically altered mice specifically to develop medulloblastoma--or, the deadliest form of brain cancer. However, they found that by shutting down the production of the gene Atoh1 they were able to prevent these mice from actually developing medulloblastoma, an aspect that researchers believe may lead to a new target in the fight against brain cancer.

And finally, back to Philadelphia - Long term exposure to secondhand smoke raises risk of breast cancer, according to another report published in the journal Cancer Epidemiology, Biomarkers & Prevention. Researchers surveyed over 57,000 women who had no smoking history, but had experienced exposure to second hand smoke at home, work, or social settings. They found that women with high amounts of exposure to secondhand smoke during adulthood, primarily postmenopausal women, had an increased risk of breast cancer. Exposure under the age of 20, however, did not appear to raise this risk.

INSIDERMEDICINE VIDEO: Balancing Protein Good For Healthy Aging, Ultrasound Beneficial in Detection of Breast Cancer For Some Women, Aspirin Does Not Prevent AMD

Wed, 2 Dec 2009 17:00:00 EDT

(December 2, 2009 - Insidermedicine)

From London - According to a report published in the journal Nature, balancing the protein in ones diet may be better for healthy aging than limiting caloric intake. Researchers fed fruit flies varying amounts of vitamins, lipids and amino acids in a diet consisting of sugar, water and yeast. The researchers were able to maximize lifespan without compromising fertility of the flies by varying the amount of amino acids, while changing the other nutrients had no such effect.

From Chicago - Women at high risk for breast cancer and have dense breasts may benefit from annual ultrasound screening, according to research presented at the annual meeting of Radiological Society of North America. Researchers studied over 600 high risk women, administering mammography and ultrasound every year. Of the 16 women that developed breast cancer, mammography alone detected 50-56% of cancers, while the addition of ultrasound detected 70-94% of cancers.

And finally, from Boston - A ten year study into the possible preventive effect of aspirin in age related macular degeneration has yielded no significant results, according to research published online in the journal Ophthalmology. Researchers studied nearly 40,000 women involved in the Women's Health Study, finding that patients who took aspirin every other day had an 18% lower risk of AMD compared with those who took placebo; this difference was deemed nonsignificant.

INSIDERMEDICINE VIDEO: Gestational Glucose Intolerance Linked With Metabolic Syndrome, Stress Response To Surgery Predicts Recovery, Mammography for Some Raises Breast Cancer Risk

Tue, 1 Dec 2009 17:00:00 EDT

(December 1, 2009 - Insidermedicine)

From Toronto - According to a report published in the Journal of Clinical Endocrinology & Metabolism, pregnant women with glucose intolerance are more likely to demonstrate cardiovascular risk factors after birth. Researchers followed nearly 500 women, looking for the prevalence of metabolic syndrome--a general term for risk factors such as obesity, high blood pressure, and low HDL cholesterol--after birth. They found an association between even mild glucose intolerance and metabolic syndrome just 3 months following birth.

From California - Patients may recover quicker from knee surgery if they have a good stress response to the operation, according to a report published in the Journal of Bone and Joint Surgery. Researchers studied 57 patients scheduled for knee surgery, counting the amount of immune cells in the blood up to 10 days before, the morning of, and 30 minutes after the operation. They found that patients whose immune system had a good stress response to surgery showed better knee function and mobility as well as less pain up to a year following the operation.

And finally, from Chicago - Radiation exposure from mammography increases the risk of breast cancer in women with a family history or genetic predisposition to the disease. For these high risk women, researchers found that low dose radiation exposure from mammography raised the likelihood of breast cancer 1.5 times, while 5 or more exposures or exposure under the age 20 resulted in a 2.5 times increased risk. This research was presented at the annual meeting of the Radiological Society of North America.

INSIDERMEDICINE VIDEO: Southern Born Americans More Likely to Die From Stroke, Patients Given Choice of Treatment Hesitant To Take Risks, Too Much Exercise Linked With Osteoarthritis

Mon, 30 Nov 2009 17:00:00 EDT

(November 30, 2009 - Insidermedicine)

From Boston - Americans born in the Southern 'stroke belt' may be at increased risk of dying from stroke, according to a report published in the journal Neurology. Researchers examined national death records from 1980, 1990, and 2000--looking specifically at Southern states that comprise the 'stroke belt'--North Carolina, South Carolina, Georgia, Tennessee, Arkansas, Mississippi, and Alabama. They found that, for people who were born in and lived in the stoke belt, 74 people per 100,000 died from stroke compared with only 47 per 100,000 who were not born in or did not live there.

From Connecticut - According to a report published in the journal Arthritis Care and Research, when patients are given the choice of their medical treatment they will usually take the conservative approach. Researchers subjected over 200 participants to 2 videos outlining medications and their serious, but rare, consequences. Participants were then given two sets of instructions, one in which the doctor essentially chose for the patient and prescribed the medication, and another in which the choice to take the medication was left completely up to the patient. Results showed that the responsibility of choosing medical treatment increased a patient's concern over the side effects and thus led to less willingness to take these treatments.

And finally, from California - Too much exercise for middle aged men and women may lead to arthritis, according to a report presented at the meeting of the Radiological Society of North America. Researchers studied 236 adults aged 45-55, finding that those who engaged in higher activity levels suffered more damage to their knees, thereby increasing their risk of developing osteoarthritis later in life.

INSIDERMEDICINE VIDEO: Diabetes To Double Within 25 Years, IV For Out of Hospital Cardiac Arrest Patients Not Beneficial, Non Confrontation at Work Bad For Heart

Fri, 27 Nov 2009 16:00:00 EDT

(November, 27, 2009 - Insidermedicine)

From Chicago – It is estimated that the number of diabetics will double and costs for their care care will triple in the next 25 years, according to a report published in the journal Diabetes Care. Researchers estimate that the prevalence of diabetes will increase from 8 million people to 14 million, and that the cost to treat these people will increase from $45 billion annually to $171 billion annually. Researchers believe that aging baby boomers are a main reason for these increases.

From Norway – According to a report published in the Journal of the American Medical Association, administering IV drugs for patients with out-of-hospital cardiac arrest does not appear to improve their survival. Based on a randomized clinical trial, researchers found that only 10% of patients survived an out of hospital cardiac arrest regardless of whether or not they received intravenous medications
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And finally from Sweden - Men who avoid confrontation at work may be at increased risk of heart attack, according to research published in the Journal of Epidemiology and Community Health. Researchers surveyed over 2,700 men, interested in how they reacted to conflict at work, including whether they walked away from confrontation. Results showed that men who engaged in 'covert coping' techniques--such as leaving an encounter or letting things pass without saying anything--had up to five times the risk of suffering heart attack or dying from heart disease in the next ten years.

INSIDERMEDICINE VIDEO: Dementia Common in Elderly in Low and Middle Income Countries, H1N1 Linked With Increase in Pneumococcal Infections, Stent No Better Than CABG

Thu, 26 Nov 2009 19:00:00 EDT

(November 26, 2009 - Insidermedicine)

From London - Dementia is the leading cause of disability in elderly people who live in low and middle income countries, according to a report published in The Lancet. Examining nearly 15,000 elderly people in seven different low to middle income countries, researchers found that dementia was, by far, the biggest contributor to disability in the elderly; the condition rated a median of 25% in population-attributable prevalence fraction.

From Atlanta - The CDC is reporting that there has been a concerning increase in the amount of serious pneumococcal infections associated with the H1N1 flu pandemic. For example, researchers point out that the the amount of pneumococcal cases in October, 2009 for the city of Denver was 58. However, the city's five year average of cases for the month of October prior to H1N1 was only 20. This increase also disproportionately affects adults between 20 and 59 years old.

And finally, back to London - Diabetic patients may benefit more from CABG than from PCI with stenting, according to a report published in the Journal of the American College of Cardiology. Researchers randomized over 500 diabetic patients suffering from multi-vessel disease to either stenting or CABG. They found that PCI failed non-inferiority tests regarding one year outcomes of myocardial infarction, stoke and death.

INSIDERMEDICINE VIDEO: Cancer Vaccine Eliminates Tumors in Mice, Active Travel Better For Health & Climate than Low Emission Vehicles, Salt Intake Affects Stroke, Heart Attack Risk

Wed, 25 Nov 2009 17:00:00 EDT

(November 25, 2009 - Insidermedicine)

From Massachusetts - For the first time, scientists have developed a cancer vaccine that can eliminate tumors in mice, according to a report published in the journal Science Translational Medicine. Researchers from Harvard University developed an implant-based vaccine. Smaller than a fingernail, the vaccine contains antigens that are tumor specific and is implanted underneath the skin, releasing cytokines and reprogramming the immune system to specifically target tumors.

From London - According to a report published in The Lancet, walking and cycling show more health and climate benefits than driving lower emission vehicles. Researchers estimated the future health and climate consequences of different transportation plans--comparing current projections (with things remaining as they are) with several alternative scenarios that included lower emission vehicles, less motor traffic, more active travel through cycling and walking and a combination of all of these. They found that active travel and less motor traffic showed as much as 40 times the health and carbon dioxide benefits when compared to only driving lower emission vehicles.

And finally, from Italy - Limiting salt intake significantly reduces risk of stroke and heart disease, according to a report published in the British Medical Journal. Researchers conducted a meta-analysis of 13 studies--covering more than 170,000 people--and found that cutting salt consumption by 5 grams a day could lower risk of stroke by 23% and heart disease by 17%.

VIDEO: Chronic Pain in Elderly Linked With Risk of Falls, Giving Birth Beneficial For Women With MS, MRSA Occurrence Rising in Hospital Outpatient Units

Tue, 24 Nov 2009 16:00:00 EDT

(November 24, 2009 - Insidermedicine)

From Boston - According to a report published in the Journal of the American Medical Association, elderly people who suffer chronic pain are at increased risk of falls. Researchers studied nearly 800 adults over the age of 70 for an 18 month period. Results showed that those who experienced chronic pain in at least two joints had a 50% increased risk of falling.

From Belgium - Women with multiple sclerosis may find that giving birth may slow progression of their condition, according to research published in the Journal of Neurology, Neurosurgery, & Psychiatry. Researchers divided 330 women with MS into four groups; those who only had children after developing MS; those who only had children before developing MS; those who had children before and after developing MS, and finally, those who did not have children at all. Results showed that women who gave birth saw their MS progress significantly slower than those who did not give birth at all.

And finally, from Washington - Community associated MRSA strains are on the rise in outpatient hospital facilities. Using information from over 300 microbiology labs, researchers found a seven fold increase in the amount of MRSA in hospital outpatients. This research was published in the journal Emerging Infectious Diseases.

INSIDERMEDICINE VIDEO: Genetic Variant Responsible For Stress Induced Hypertension, Most Chemotherapy Patients Suffer Insomnia, Children Watching More TV at Daycare

Mon, 23 Nov 2009 17:00:00 EDT

(November 23, 2009 - Insidermedicine)

From Germany - Stress-induced hypertension may arise from variation of the phosducin gene, according to a report published in the Journal of Clinical Investigation. Researchers generated mice that did not have the phosducin gene, finding that they had higher baseline blood pressure than normal mice as well as a higher blood pressure response to stress. When this gene was studied in humans, researchers found that one particular phosducin gene variation was also associated with higher baseline blood pressure.

From New York - Most cancer patients who receive chemotherapy consequently suffer from insomnia. Researchers surveyed over 800 cancer patients who had undergone their first two chemotherapy treatments. Results showed that three quarters of these patients suffered from either insomnia or other sleep-related disorders. This research was published in the Journal of Clinical Oncology.

And finally, from Washington - According to a report published in the journal Pediatrics, children in home-based daycare watch twice as much TV has those in center-based daycare. Researchers studied nearly 170 different child care programs. Preschool aged children in home based daycares watched an average of 2.4 hours of TV a day, while children in center based daycares watched only 0 .4 hours per day.

INSIDERMEDICINE VIDEO: Genetic Sonogram Effective Test for Down Syndrome, TACE Followed By Liver Transplant Best For Liver Cancer Patients, Depressed Mothers Affect Asthmatic Children

Fri, 20 Nov 2009 17:00:00 EDT

(November 20, 2009 - Insidermedicine)

From Houston - A genetic sonogram significantly strengthens Down syndrome detection when used along with typical non-invasive testing, according to research published in the journal Obstetrics and Gynecology. Studying over 8,000 pregnant women, researchers found that ultrasound alone had a 69% detection rate of Down syndrome. However, ultrasound combined with non-invasive biochemical screening resulted in a 98% detection rate as well as a decrease in the number of false positive tests results.

From Los Angeles - Patients with unresectable liver cancer benefit the most from triple-drug transcatheter arterial chemoemobilization (TACE) followed with liver transplantation. Researchers studied 124 patients with unresectable liver cancer; 28 of whom underwent triple drug TACE and liver transplant and 96 who only underwent triple drug TACE. Median survival in the liver transplant group was 97 months more than those who underwent triple drug TACE alone. This research was published in the American Journal of Roentgenology.

And finally, from Baltimore - Children with asthma may see their symptoms worsen if they have a depressed mother, according to research presented in the Journal of Pediatric Psychology. Researchers studied 262 mothers of children with asthma. They found that children whose mothers were depressed had more frequent asthma symptoms over 6 months than those whose mothers were not depressed.

VIDEO: Laser Therapy Worsens Skin Cancer, Pregnant Women With MS At No Increased Risk of Complications, Kidney Transplant Patients With Sleep Apnea More Likely To Get Heart Disease

Thu, 19 Nov 2009 19:00:00 EDT

(November 19, 2009 - Insidermedicine)

From Norway – Low level laser therapy can worsen skin cancer, and thus should not be used over melanomas. Researchers injected mice with melanoma cancer cells and applied cold laser therapy. They found that the laser therapy aggravated the skin cancer and increased the growth of the melanoma tumor. This research was published in the journal BMC Cancer.

From California - Pregnant women with MS are no more likely to develop complications than other women, according to a report published in the journal Neurology. Researchers analyzed information on over 18 million births, 10, 000 of which were delivered by women with MS. They found that, while women with MS were more likely to have slower growing fetuses and give birth via caesarian section, they were no more likely than other women to suffer pregnancy complications such as preeclampsia..

And finally, from Hungary – According a report published in the Clinical Journal of the American Society of Nephrology, sleep apnea in kidney transplant patients increases their risk of stroke or heart disease. In a study of over 100 kidney transplant patients, researchers found that 25% suffered from sleep apnea and had twice the risk of developing heart disease or stroke than transplant patients without apnea.

VIDEO: FDA Warns of Plavix and Prilosec Combination, New Research Into Elderly Immune Response to Viral Infection, Active Video Games Equivalent to Exercise

Wed, 18 Nov 2009 17:00:00 EDT

(November 18, 2009 - Insidermedicine)

From Washington - Using Prilosec in combination with Plavix dramatically reduces the effectiveness of Plavix, according to a report released by the FDA. Because Plavix sometimes causes an upset stomach, many people turn to the antacid Prilosec. However, studies from the manufacturer of clopidogrel reveal that this particular combination reduces Plavix effectiveness by 50%, increasing ones risk for heart attack or stroke.

From Connecticut - According to research published in the journal Cell Host & Microbe, elderly people are more susceptible to death from viral infections because they have overactive immune systems. Infecting mice of all ages with the herpes virus, scientists found that only aged mice were suffering liver damage. However, when researchers restrained the aged mice's cytokines--a molecule that allows cells of the immune system to communicate with one another--they found that the mice no longer died nor suffered damage to their livers.

And finally, from Orlando - Playing active video games may be equivalent to moderate exercise, as these games actually cause people to sweat. Researchers studied 12 healthy men and women while they played a variety of sports and fitness active video games. Results showed that, for a 33% of the games played, each person expended an amount of energy that was equivalent to walking on a treadmill at at least three miles an hour. This study was presented at the annual meeting of the American Heart Association.

VIDEO: Uninsured Trauma Patients More Likely To Die, New Recommendations Regarding Mammography Screening, New Approach to Help Post CABG Patients With Depression

Tue, 17 Nov 2009 17:00:00 EDT

(November 17, 2009 - Insidermedicine)

From Boston - According to a report published in the Archives of Surgery, trauma patients without health insurance are at significantly increased risk of mortality. Researchers studied nearly 700,000 trauma cases, adjusting for factors such as comorbidities and the severity of the injury incurred. They found that trauma patients without insurance were at 89% increased risk of death.

From Washington - The US Preventive Services Task Force is recommending that women do not need to undergo routine mammogram screening for breast cancer until the age of 50. This screening is to take place only every two years. Researchers found that: younger women are more likely to have false-positive diagnoses; over-diagnosis occurs 1 to 10% of the time because of screening; and breast self-examination does not appear to decrease risk of mortality. This research is published in the Archives of Internal Medicine.

And finally, from Orlando - According to research presented at the annual meeting of the American Heart Association, phone calls from a nurse may help patients who are suffering depression after undergoing CABG. Researchers studied over 300 post-op CABG patients who were suffering from depression, randomizing some to traditional anti-depressive therapy and others to an intervention program in which a nurse called patients and talked to them about depression. Patients who received these phone calls saw their depression symptom scores improve more than those who received traditional therapy.

VIDEO: Heart Disease Patients May Benefit From Transcendental Meditation, New International Study of Schizophrenia, Heart Failure Patients Have Impaired Response to Exercise

Mon, 16 Nov 2009 17:20:00 EDT

(November 16, 2009 - Insidermedicine)

From Orlando - According to research presented at the annual meeting of the American Heart Association, heart disease patients find their risk of heart attack, stroke and death drastically reduced if they practice transcendental meditation. For nine years, researchers studied over 200 adult men and women suffering from heart disease, randomly assigning one group to practice transcendental meditation and the other to take part in a dietary modification and exercise program. They found that patients who practiced transcendental meditation had a 47% lower rate of heart attacks, stokes and death when compared to the other group.

From Toronto - According to research published in the International Journal of Clinical Practice, a recent international study of schizophrenia has revealed interesting similarities of the condition regardless of region, economy and culture. Studying over 17,000 schizophrenic patients in 37 different countries, researchers found the following: only 19% of patients were in paid employment; 62% reported sexual dysfunction; nearly 70% lived in dependent housing; and 74% were taking additional prescribed drugs along with their antipsychotic medication.

And finally, back to Orlando - Patients with heart failure and a normal left ventricular ejection fraction may find their heart rate has an impaired response to exercise, according to another report presented at the annual meeting of the American Heart Association. Researchers studied over 80 patients, comparing those who had heart failure and preserved LVEF and with a control group of healthy patients. Those with heart failure had lower peak heart rate response as well as lower change in heart rate during exercise when compared to the healthy group.

VIDEO: New H1N1 Statistics From the CDC, Baby Boomers Face High Disability Rates, Pregnant Women Okay to Exercise Until End of Third Trimester

Fri, 13 Nov 2009 17:00:00 EDT

(November 13, 2009 - Insidermedicine)

From Atlanta - According to new statistics released by the CDC, 22 million Americans have been infected with the H1N1 flu in the last six months. In that same time period, roughly 3,900 people have died from H1N1, with 540 of these deaths being pediatric. Furthermore, of the 98, 000 H1N1 patients hospitalized, 36, 000 were 17 years or younger. Over 2,900 patients who have died from H1N1 were between ages 18 and 64.

From Los Angeles - Individuals now entering their 60s--or baby boomers--face unusually high disability rates, according to a report published in the American Journal of Public Health. Researchers analyzed information from the National Health and Nutrition Examination surveys, comparing the mobility and independence of baby boomers with that of the previous generation. Results showed that disability rates in both aspects have increased between 40 and 70% for the baby boom generation.

And finally, from Madrid - Exercising up until the end of pregnancy is beneficial for both mother and child, according to a report published in the International Journal of Obesity. Researchers studied 160 pregnant women between 25 and 35 years old, half of whom took part in a supervised exercise regimen. Results showed that exercise in the second and third trimester had no negative effect on fetal health, but rather, made it less likely for the mother to have a heavier child.

VIDEO: High Hemoglobin Levels Predictor of Diabetic Retinopathy, Old People More Likely to Die from H1N1, Western Diet Linked to Obesity Through Gut Microbes

Thu, 12 Nov 2009 17:00:00 EDT

(November 12, 2009 - Insidermedicine)

From Pittsburgh - High hemoglobin levels may be a predictor of diabetic retinopathy later in life, according to a report published in the Archives of Ophthalmology. Researchers followed 426 diabetic patients for 18 years. For ever 1 g/dl increase in hemoglobin levels, men were at 29% increased risk of diabetic retinopathy, while women saw their risk increase by 10%.

From Mexico - While young people are more likely to get the H1N1 flu, older people are more likely to die from it, according to a report published in The Lancet. Researchers found several interesting statistics on over 63, 000 cases of flu-like illnesses studied: 10.3% of those aged 70 and older who were infected died, while only 0.9% of those aged 20-29 died; 6% of pregnant women with H1N1 died; nearly 1% of all H1N1 cases died; the risk of catching H1N1 fell by 35% for those vaccinated for the seasonal flu; chronic underlying illnesses raised risk 6 fold; and finally, people who did not go to the hospital within four days of developing H1N1 symptoms had a 20% increased risk of death for each day they put off going to the hospital.

And finally, from St. Louis - According to a report published in the journal Science Translational Medicine, a Westernized diet may lead to obesity through microbes found in the gut. Researchers implanted human intestinal microbes into mice and changed the rodents food from a plant based, low fat diet to a diet high in both fats and sugars. Results showed that microbes linked with obesity were immediately found in the mice intestines after the change in diet, with the mice eventually becoming obese.

VIDEO: Obesity Linked With Left Atrium Enlargement, Hospitals Typically Do Not Explain Adverse Effects of Treatment to Patients, Back Pain Affecting US Soldiers

Tue, 10 Nov 2009 17:00:00 EDT

(November 10, 2009 - Insidermedicine)

From Germany – According to research published in the Journal of the American College of Cardiology, obesity greatly increases ones chances of having an enlarged left atrium. Researchers examined information on over 1200 adults, administering echocardiograms at the beginning of the study as well as ten years later. Results showed that obesity increased the risk of left atrial enlargement by 2.5 times.

From Boston – Patients who suffer adverse effects from hospital treatment do not typically receive explanations from medical personnel, according to a report published in the Archives of Internal Medicine. Surveying over 2,500 patients recently discharged from the hospital, researchers reported a total of 845 adverse events. Only 39.5% of the time were these adverse events actually explained to the patient by medical personnel.

And finally, from Baltimore – According to another report published in the Archives of Internal Medicine, US soldiers are frequently unable to return to combat because of back pain. Researchers reviewed information on over 1,400 soldiers evacuated from either Iraq or Afghanistan who were suffering back pain. Results showed that only 13% of these soldiers actually returned to duty following their evacuation.

VIDEO: Hospitalization for COPD Patients Possibly Dependent on Type of Treatment, Dense Breast Raises Risk of Breast Cancer Recurrence, Early PSA Levels Linked With Mortality Risk

Mon, 9 Nov 2009 17:00:00 EDT

(November 9, 2009 - Insidermedicine)

From San Diego - According to research presented at the American College of Chest Physicians meeting, the risk of hospitalization for COPD patients may be dependent on the type of bronchodilator they use. Researchers examined the cases of over 50, 000 COPD patients, dividing the patients into five different treatment groups. Results showed that monotherapy with tiotropium had the lowest amount of hospitalizations.

From Toronto - Women who have dense breasts and breast cancer may be at higher risk of recurrence, according to a report published in the journal Cancer. Researchers reviewed over 335 breast cancer patients, all of whom had their breast density assessed before undergoing breast conserving surgery. Results showed that women with high breast density had 6 times the recurrence rate after undergoing surgery.

And finally, from Chicago - According to a report presented at the meeting for the American Society of Radiation Oncology, prostate cancer patients who have early rising PSA levels after radiation therapy are at increased risk of mortality. Researchers examined records on over 6000 prostate cancer patients treated with radiation therapy. Survival rates after 5 years were 20% lower for patients who had biochemical failure within 18 months of treatment as opposed to those whose PSA failure occurred after 18 months.

VIDEO: Cries of Baby Mimic Mothers Language, Pollution Linked With Bronchiolitis, Home Fetal Heart Monitors Not to Be Relied Upon

Fri, 6 Nov 2009 16:00:00 EDT

(November 6, 2009 - Insidermedicine)

From Germany - According to a report published in the journal Current Biology, babies cries mimic the intonations of their mothers language. Researchers compared the cries of 60 French and German babies. They found that the German newborns cries had a 'falling' melody, much like the German language, while French babies cries had a rising accent that mimicked French inflections. These findings, researchers believe, indicate that babies imitate the sound of the language that first makes it through to the womb.

From Washington - Heavy air pollution increases an infants risk of bronchiolitis, according to a report published in the American Journal of Respiratory and Critical Care Medicine. Researchers studied nearly 12,000 infant bronchiolitis cases, analyzing the ambient pollution exposure 10 km within the child's home. Results showed that increased exposure to nitric oxide, nitrogen dioxide, carbon monoxide, and sulfur dioxide all raised an infants risk of bronchiolitis.

And finally, from England - According to a report published in the British Medical Journal, pregnant women should not rely on home fetal heart monitors to indicate the health of the fetus. Researchers suggest that an untrained ear may misinterpret sounds from the monitor as reassurance, when in fact something may be wrong and the sounds could be the mothers pulse or placental flow.

VIDEO: No Advantage For Off Pump Heart Surgery, X Rays For Mechanical Ventilation Patients Taken As Needed, Green Tea Good Against Oral Cancer

Thu, 5 Nov 2009 19:00:00 EDT

(November 5, 2009 - Insidermedicine)

From Colorado - Coronary artery bypass surgery without a heart-lung machine has been shown to be no better than the traditional 'on-pump' process, according to a report published in the New England Journal of Medicine. Researchers examined over 2000 patients; half underwent surgery aided by use of a heart-lung machine (or, 'on-pump') while the other half underwent surgery with their heart still beating (or, 'off-pump'). Results showed that both procedures had similar outcomes after 30 days, though outcomes after a year appeared to favor the on-pump procedure.

From Paris - According to a report published in The Lancet, x rays for mechanically ventilated patients should be taken only as needed. Researchers examined 21 different ICUs, randomly conducting either routine, daily chest x rays on patients or x rays as needed. Results showed a 32% reduction of the amount of x rays taken with the as needed approach, with no difference in the amount of diagnostic interventions.

And finally, from Houston - According to a report published in the journal Cancer Prevention Research, green tea may have promise as an oral cancer prevention agent. For nearly 6 years, researchers studied 41 oral leukoplakia patients--administering either green tea extract or placebo. They found that 58.8% of patients who took the green tea extract had a clinical response, compared with only 18.2% on placebo.

VIDEO: Low Cholesterol Linked With Reduced Risk of Cancer, Light Cigarettes Make It Harder to Quit Smoking, HER2 Positive Breast Tumors More Likely to Recur

Wed, 4 Nov 2009 17:00:00 EDT

(November 4, 2009 - Insidermedicine)

From Boston – According to a report published in the journal Cancer Epidemiology, Biomarkers and Prevention, low blood cholesterol levels may reduce risk of prostate cancer. Researchers studied over 5500 men aged 55 and older. For men with cholesterol levels under 200, results showed a 59% reduced risk of developing high grade prostate tumors.

From Pittsburgh – Lite, low tar, or mild cigarettes actually make it harder for smokers to quit, according to research published in the journal Tobacco Control. Researchers surveyed over 30, 000 smokers, 12,000 of whom smoked a ‘light’ brand of cigarettes. Results showed that people who smoked lite cigarettes were 46% less likely to give up smoking.

And finally, from Houston - According to a report published in the Journal of Clinical Oncology, even small HER2 positive breast tumors are more likely to recur within 5 years. Examining nearly 1000 women diagnosed with breast cancer in a twelve year period, researchers found that women with HER-2 positive tumors were at a five times increased risk of metastases if the cancer returned.

VIDEO: Nicotine Patch Plus Lozenge Best Approach to Quit Smoking, Obese HIV Patients Have Slower Immune Response to Therapy, Midlife Hypertension Linked With Alzheimer's

Tue, 3 Nov 2009 17:00:00 EDT

(November 3, 2009 - Insidermedicine)

From Wisconsin - According to a report published in the Archives of General Psychiatry, smokers who want to quit may find that the best approach is to use both a nicotine patch and lozenges. Researchers studied over 1500 adult smokers, randomizing participants to five different smoking cessation regimens. After six months, those who took the patch plus lozenge were less likely to smoke than those who took the other treatments.

From Philadelphia - According to a report presented at the meeting of the Infectious Diseases Society of America, obese HIV patients have a slower immune response to antiretroviral treatment than HIV patients of normal weight. Using data from the US Military Natural History Study, researchers examined the BMIs of over 1100 HIV patients. They found that patients with a BMI greater than 30 regained less CD4-positive T cells following treatment than those whose BMI was between 18.5 and 24.9.

And finally, from the Netherlands - Middle aged hypertension may be a predictor of Alzheimer's disease later in life, according to another report published in the Archives of General Psychiatry. Dutch researchers studied nearly 200 families, half whom had parents with late-onset Alzheimer's disease and the other half with no history of the condition. They found that 40% of middle aged offspring of parents with Alzheimer's had high blood pressure, compared with only 29% of offspring with no family history of dementia.